Esfam Biotech


Esfam Biotech is a Melbourne-based biotech company focused on world-first molecular research into significant diseases affecting global populations. They develop small molecules with novel mechanisms of action for late-stage oncology and respiratory diseases, and are engaged in groundbreaking research targeting COVID-19, prostate cancer, and viral infections in pigs. Their mission is to bring scientific breakthroughs to market to improve global health.

Industries

biopharma
biotechnology
pharmaceutical

Nr. of Employees

small (1-50)

Esfam Biotech

C/o Department of Clinical Pharmacology and Theraputics Austin Health, Level 5, Townsend Building, Sudley Road, Heidelberg Victoria 3084, Australia


Patents

CD151 inhibitors

US-12215112-B2

View Details

Products

Antiviral small-molecule candidate for SARS-CoV-2 (preclinical)

A small-molecule candidate designed to block SARS-CoV-2 binding to host cells via a mechanism distinct from ACE2 interaction; demonstrated prophylactic and therapeutic activity in cell-based assays and animal models and being developed as injectable and inhalational formulations.

Small-molecule oncology candidate for advanced prostate cancer (preclinical)

A non-hormonal small-molecule candidate that has shown potent anti-cancer effects in cell and animal models against prostate cancers unresponsive to hormone blockade; progressing through preclinical evaluation toward human trials.

Veterinary antiviral candidate for PRRS (preclinical)

Small-molecule inhibitors identified that block PRRS virus binding in cell-based assays with planned progression to animal testing for a first-in-class agricultural therapeutic.


Services

End-to-end discovery and preclinical development of small‑molecule therapeutics, including target identification, in silico design, cell and animal efficacy testing, formulation development and preparation for clinical entry.

Expertise Areas

  • Small-molecule drug discovery
  • Computational drug design
  • Preclinical development (cell assays and animal models)
  • Inhalation and injectable formulation development
  • Show More (6)

Key Technologies

  • In silico molecular modelling
  • Cell-based antiviral and oncology assays
  • Animal efficacy models
  • Dry powder inhalation formulation
  • Show More (4)

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