EpiBone, Inc.
EpiBone is dedicated to transforming skeletal repair through groundbreaking research and engineering. Their mission is to help people live happier and more active lives by regrowing bone and cartilage using stem cells, without the need for artificial grafts or implants. They focus on personalized, lifelong tissue growth that integrates seamlessly with the body, aiming to address the root causes of skeletal conditions and reduce long-term disability.
Industries
Nr. of Employees
small (1-50)
EpiBone, Inc.
Products
Tissue-engineered patient-specific autologous bone graft for craniofacial reconstruction
A CT-customized, tissue-engineered autologous bone graft produced from a patient's adipose-derived stem cells and grown on an osteogenic scaffold for facial bone defects.
Allogeneic tissue-engineered osteochondral implant (osteochondral plug)
An osteochondral plug composed of condensed mesenchymal cells on a bone scaffold with an engineered cartilage layer, cultivated under cyclical mechanical loading and perfusion to treat high-grade cartilage lesions.
Allogeneic injectable cartilage filler
An injectable cartilage product consisting of primed condensed mesenchymal cells combined with a hydrogel carrier, intended for low-grade cartilage lesions without bone involvement; components can be stored for scheduling flexibility.
Tissue-engineered patient-specific autologous bone graft for craniofacial reconstruction
A CT-customized, tissue-engineered autologous bone graft produced from a patient's adipose-derived stem cells and grown on an osteogenic scaffold for facial bone defects.
Allogeneic tissue-engineered osteochondral implant (osteochondral plug)
An osteochondral plug composed of condensed mesenchymal cells on a bone scaffold with an engineered cartilage layer, cultivated under cyclical mechanical loading and perfusion to treat high-grade cartilage lesions.
Allogeneic injectable cartilage filler
An injectable cartilage product consisting of primed condensed mesenchymal cells combined with a hydrogel carrier, intended for low-grade cartilage lesions without bone involvement; components can be stored for scheduling flexibility.
Services
Custom tissue manufacturing (patient-specific bone and cartilage grafts)
End-to-end manufacturing of anatomically shaped bone and cartilage grafts using patient imaging, stem-cell processing, scaffold/hydrogel systems, and bioreactor culture.
Preclinical testing and translational study support
Large-animal implantation studies and translational research to validate engineered tissue function prior to clinical trials.
Clinical trial execution and enrollment support
Designs and conducts early-phase clinical trials for tissue-engineered skeletal products, including IND-enabled studies.
Custom tissue manufacturing (patient-specific bone and cartilage grafts)
End-to-end manufacturing of anatomically shaped bone and cartilage grafts using patient imaging, stem-cell processing, scaffold/hydrogel systems, and bioreactor culture.
Preclinical testing and translational study support
Large-animal implantation studies and translational research to validate engineered tissue function prior to clinical trials.
Clinical trial execution and enrollment support
Designs and conducts early-phase clinical trials for tissue-engineered skeletal products, including IND-enabled studies.
Expertise Areas
- Tissue engineering for bone and cartilage
- Personalized/ patient-specific graft manufacturing
- Bioreactor development and bioprocessing
- Stem cell sourcing and processing
Key Technologies
- Custom bioreactor systems
- CT-based 3D anatomical modeling
- Adipose-derived stem cell isolation
- Mesenchymal condensation