Dillico
Dillico is a deeptech startup (Meylan/Grenoble, France) developing an integrated, continuous and digitized manufacturing solution for mRNA drug products. The company focuses on a flow-chemistry based, all-scale approach that aims to produce formulated mRNA-LNPs from development through commercial scale using the same equipment, and to provide associated automation, analytics and process development services.
Industries
N/A
Products
Integrated continuous mRNA-LNP manufacturing platform
An integrated, compact continuous platform that combines flow-chemistry formulation, downstream unit operations and digitized control to produce formulated mRNA-LNPs across development and commercial scales.
Integrated continuous mRNA-LNP manufacturing platform
An integrated, compact continuous platform that combines flow-chemistry formulation, downstream unit operations and digitized control to produce formulated mRNA-LNPs across development and commercial scales.
Services
Process development for mRNA-LNP
Downstream, encapsulation and formulation development, scale-down experiments, process characterization and transfer to pilot/GMP-like systems.
Automation, commissioning and qualification services
Automation strategy, PLC/DCS integration, FAT/SAT/IQ/OQ preparation and execution, and supplier coordination for GMP equipment.
Digital twin and bioprocess data services
Development of inline digital twin, dashboards, data pipelines and historian/database solutions for process monitoring and decision support.
Pilot testing and equipment commercialization support
Pilot-scale testing, proof-of-concept validation and support for early commercialization of continuous manufacturing equipment.
Process development for mRNA-LNP
Downstream, encapsulation and formulation development, scale-down experiments, process characterization and transfer to pilot/GMP-like systems.
Automation, commissioning and qualification services
Automation strategy, PLC/DCS integration, FAT/SAT/IQ/OQ preparation and execution, and supplier coordination for GMP equipment.
Digital twin and bioprocess data services
Development of inline digital twin, dashboards, data pipelines and historian/database solutions for process monitoring and decision support.
Pilot testing and equipment commercialization support
Pilot-scale testing, proof-of-concept validation and support for early commercialization of continuous manufacturing equipment.
Expertise Areas
- Continuous mRNA manufacturing
- mRNA-LNP formulation and encapsulation
- Downstream process development (chromatography, TFF, sterile filtration)
- Process modeling, DoE and scale-down development
Key Technologies
- Meso-fluidic flow chemistry
- Continuous manufacturing platforms
- Lipid nanoparticle (LNP) formulation
- Chromatography for large molecules