CureLab Oncology


CureLab Veterinary is a biotechnology company focused on the development of gene-based therapies targeting cancer and chronic inflammatory diseases in companion animals, such as dogs, cats, and horses. Utilizing advances in comparative medicine and translational immunology, the company applies a plasmid-based platform to stimulate anti-cancer immune responses, modulate tumor microenvironments, and mitigate chronic inflammation. Clinical research leverages academic partnerships and a robust intellectual property portfolio, pursuing efficient regulatory approval pathways in major markets, including the US and Europe. Recent studies suggest broader applications in pain management and cross-species translational potential.

Industries

N/A

Nr. of Employees

small (1-50)


Patents

Methods and compositions relating to p62/SQSTM1 for the treatment and prevention of inflammation-associated diseases

US-11098098-B2

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Methods and compositions relating to P62 for the treatment and prophylaxis of cancer

US-10716837-B2

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Methods and compositions relating to P62 for the treatment and prophylaxis of cancer

US-9717781-B2

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Products

Plasmid DNA therapy for cancer, chronic inflammation, and pain in companion animals

A gene therapy platform using circular DNA plasmid encoding p62/SQSTM1, delivered via intramuscular injection, aimed at enhancing anti-cancer immune responses, remodeling the tumor microenvironment, and modulating inflammation and chronic pain.


Services

Collaboration opportunities for academic and private veterinary clinics to participate in clinical research programs focusing on gene-based therapies for cancer, chronic inflammatory diseases, and pain in companion animals.

Expertise Areas

  • Comparative oncology
  • Veterinary gene therapy
  • Translational medicine
  • Chronic inflammatory disease research
  • Show More (4)

Key Technologies

  • Gene therapy using plasmid DNA
  • Cancer immunotherapy
  • Chronic inflammation modulation
  • Mesenchymal stem cell modulation
  • Show More (2)

News & Updates

Announced partnership with the University of Camerino to advance research on gene therapy for companion animal cancer and inflammatory diseases.

Initiated Regulation D fundraising offering targeting $15 million to support regulatory and manufacturing milestones for cancer and inflammation treatments for pets.

Appointed Alexis Nahama, DVM, as Executive Vice-President to lead business development and strategic partnerships.

Engaged with the USDA Center for Veterinary Biologics to advance licensing for key therapies.

An open-label study involving 17 dogs showed 90% response to gene therapy for chronic osteoarthritis pain, without significant adverse effects, positioning the technology as a potential non-opioid path for pain management.

Filed a patent application for DNA plasmid-based chronic pain treatment, addressing inflammation-driven pain in veterinary and potential human applications.

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