Bitrobius Genetics
Developing a plasmid-based gene-therapy platform that delivers self-replicating DNA to target organs, enabling intercellular spread of corrective genes. The organisation focuses on engineering plasmid constructs that express therapeutic proteins, replicate within cells, and translocate between adjacent cells, and is adapting the approach for mitochondrial gene delivery. The site states an emphasis on developing therapies for genetic diseases lacking effective treatments and on enabling more scalable manufacture compared with current viral-vector approaches.
Industries
Nr. of Employees
small (1-50)
Products
Plasmid-based intercellular gene-delivery platform
A platform using plasmid DNA that replicates in host cells, expresses therapeutic proteins, and translocates to adjacent cells to spread corrective genetic material across affected tissues; being adapted for mitochondrial delivery.
Gentrafix
Groundbreaking plasmid technology that delivers therapeutic proteins directly to target cells, offering a revolutionary approach to curing genetic diseases.
Plasmid-based intercellular gene-delivery platform
A platform using plasmid DNA that replicates in host cells, expresses therapeutic proteins, and translocates to adjacent cells to spread corrective genetic material across affected tissues; being adapted for mitochondrial delivery.
Gentrafix
Groundbreaking plasmid technology that delivers therapeutic proteins directly to target cells, offering a revolutionary approach to curing genetic diseases.
Services
Engagements with funders and research partners to support development and translation of plasmid-based gene therapies.
Engagements with funders and research partners to support development and translation of plasmid-based gene therapies.
Expertise Areas
- Plasmid engineering
- Gene therapy platform development
- Mitochondrial gene therapy
- Preclinical therapeutic development
Key Technologies
- Plasmid-based gene delivery
- Intercellular DNA translocation
- Mitochondrial DNA translocation
- Therapeutic gene expression from plasmids