CritiTech

A proprietary technology and process aimed at optimizing the specific surface area of drugs by modifying particle characteristics such as size, shape, and polymorph.

Specialized experience and technology dedicated to dry powder inhalation development and respiratory drug development services.

Specialized experience and proven proprietary technology leading to advances in inhaled drug formulations.

Batch supercritical fluid CO2 system for proof of concept and development, capable of non-cytotoxic and cytotoxic handling.

Batch supercritical fluid CO2 system for proof of concept and development, capable of non-cytotoxic and cytotoxic handling.

Supercritical fluid CO2 batch processing system designed for proof of concept, development, and handling cytotoxic or non-cytotoxic compounds.

Supercritical fluid CO2 batch processing system designed for proof of concept, development, and handling cytotoxic or non-cytotoxic compounds.

Comprehensive analytical testing and material characterization services offered by CritiTech to support drug development projects from proof-of-concept through clinical production.

CritiTech offers pharmaceutical analytical method development and validation services combining proficiency and creativity to ensure quality and reliability of test results.

Facilities expansion including separate cytotoxic and non-cytotoxic buildings, additional GMP suites, and fill-finish services.

Contract fill-finish services including blending, capsule-filling, and vial-filling for clinical trials.

Comprehensive CDMO services offering POC to GMP production, specialized in handling potent and non-potent APIs, oxygen-sensitive and hygroscopic compounds using nitrogen systems, and producing dispersions and powders.

State-of-the-art contract spray drying services for pharmaceutical applications, converting liquid formulations into fine powders for enhanced drug delivery, bioavailability, and controlled release.

Continuous supercritical fluid CO2 processing system designed for manufacturing and development.

CDMO services providing particle engineering, drug formulation, spray drying, analytical testing, and fill-finish capabilities for cytotoxic and non-cytotoxic drugs in dedicated facilities.

Pharmaceutical particle engineering services utilizing spray drying and supercritical precipitation to solve bioavailability challenges and optimize drug product profiles.

Continuous supercritical fluid CO2 system designed for cGMP manufacturing and cytotoxic handling.

Robust spray drying capabilities from proof of concept to GMP, handling cytotoxic and potent API compounds.

Customized pharmaceutical development and manufacturing services utilizing spray drying and supercritical precipitation technology for non-GMP and cGMP materials.

cGMP Phase I and II spray drying manufacturing unit designed for scale-up and commercial particle engineering.

cGMP compliant spray drying system designed for production-scale pharmaceutical manufacturing.

Continuous supercritical fluid CO2 system for cGMP manufacturing with high capacity scales.

Supercritical precipitation particle engineering technology offered by CritiTech for pharmaceutical applications.

Inhaled NanoPac (Purcision Paclitaxel) engineered via Purcision technology, demonstrating high concentration and long duration in the lungs.

Large scale continuous supercritical fluid CO2 processing system for cGMP manufacturing.

Pre-formulation services to help clients develop the right formulation early in the drug development process, including drug substance characterization, solubility screening, excipient screening, formulation techniques, and formulation stability.

Particle size reduction service utilizing particle-to-particle collisions by suspending coarse powder in a high-volume air flow.

Robust pharmaceutical quality assurance systems ranging from non-GMP pre-clinical work through GMP production manufacturing, ensuring products meet safety, efficacy, and compliance standards.

Oncology drug product developed for high-risk non-muscle invasive bladder cancer and other indications.

Proof of concept laboratory spray dryer used for feasibility testing and initial particle engineering.

Manual vial filler for non-cytotoxic materials supporting POC to Phase III GMP.

Lab blender with intensifier bar supporting POC to Phase II GMP for non-cytotoxic materials.

Semi-automated vial filler for cytotoxic materials supporting POC to Phase III GMP.

Automated capsule filler for non-cytotoxic materials supporting POC to Phase II GMP with tooling for 000-5 available.