Cocoon Bioscience S.L.
Cocoon Bioscience is a pioneering company that leverages nature-based technology, specifically using insects in a chrysalis state, to produce high-performance, complex recombinant proteins such as growth factors and enzymes. Their mission is to break down bottlenecks in protein production, making progress more accessible and sustainable, with applications spanning life sciences, foodtech, cellular agriculture, biopharmaceuticals, and cosmetics. They focus on affordability, scalability, and high quality, adhering to GMP standards and promoting sustainability.
Industries
Nr. of Employees
small (1-50)
Cocoon Bioscience S.L.
Madrid, Madrid, Spain, Europe
Products
Recombinant human FGF-2 (growth factor)
Human basic fibroblast growth factor produced in an insect-based expression system; provided with sequence, molecular weight (~18.5 kDa), formulation and measured purity and bioactivity data.
Recombinant human EGF (growth factor)
Human epidermal growth factor produced in an insect-based expression system; product information includes sequence, molecular weight (~7.5 kDa), formulation, purity and bioactivity (ED50) data.
Recombinant PDGF (human and porcine)
Platelet-derived growth factor isoforms (human and porcine PDGF‑BB) produced in an insect-based expression system; product pages provide sequence, formulation, purity and bioactivity specifications.
Specialty recombinant enzymes (custom and off-the-shelf)
Custom and specialty enzymes produced in the insect-based expression system with a focus on enzymes that modify nucleic acids (polymerases, nucleases, ligases) and other application-specific enzymes.
Recombinant human FGF-2 (growth factor)
Human basic fibroblast growth factor produced in an insect-based expression system; provided with sequence, molecular weight (~18.5 kDa), formulation and measured purity and bioactivity data.
Recombinant human EGF (growth factor)
Human epidermal growth factor produced in an insect-based expression system; product information includes sequence, molecular weight (~7.5 kDa), formulation, purity and bioactivity (ED50) data.
Recombinant PDGF (human and porcine)
Platelet-derived growth factor isoforms (human and porcine PDGF‑BB) produced in an insect-based expression system; product pages provide sequence, formulation, purity and bioactivity specifications.
Specialty recombinant enzymes (custom and off-the-shelf)
Custom and specialty enzymes produced in the insect-based expression system with a focus on enzymes that modify nucleic acids (polymerases, nucleases, ligases) and other application-specific enzymes.
Services
Custom recombinant protein development
Project-based development from sequence assessment and gene synthesis to virus production, insect-based expression, downstream optimization and delivery of proof-of-concept samples followed by staged scale-up and GMP production.
Proof-of-concept enzyme expression program (fee-based)
Paid PoC program for custom or difficult-to-express enzymes, enabling rapid prototyping and testing of enzyme expression in the insect-based system.
Distributor and commercial partnership support
Program to partner with distributors and commercial partners for product distribution and portfolio integration.
Custom recombinant protein development
Project-based development from sequence assessment and gene synthesis to virus production, insect-based expression, downstream optimization and delivery of proof-of-concept samples followed by staged scale-up and GMP production.
Proof-of-concept enzyme expression program (fee-based)
Paid PoC program for custom or difficult-to-express enzymes, enabling rapid prototyping and testing of enzyme expression in the insect-based system.
Distributor and commercial partnership support
Program to partner with distributors and commercial partners for product distribution and portfolio integration.
Expertise Areas
- Recombinant protein expression using insect-based BEVS
- Specialty enzyme development for mRNA and gene sequencing workflows
- Recombinant growth factor production for cell culture and cellular agriculture
- Custom recombinant protein development and rapid proof-of-concept testing
Key Technologies
- Baculovirus expression vector system (BEVS)
- Insect cocoon-based bioreactors
- Gene synthesis and viral vector production
- Downstream purification technologies