Cleave Biosciences


Biopharmaceutical company focused on discovery and development of small-molecule inhibitors that disrupt cellular protein homeostasis for oncology. Activities include target discovery and validation for ATPase and metalloprotease families, medicinal chemistry, preclinical efficacy testing, biomarker identification, translational development into early-phase clinical trials, and provision of laboratory reagents and educational content in proteomics.

Industries

health-care
medical-device
therapeutics

Nr. of Employees

small (1-50)

Cleave Biosciences

6017 Snell Avenue, San Jose, CA 95123, United States


Patents

Fused pyrimidines as inhibitors of p97 complex

US-10174005-B2

View Details

Fused pyrimidines as inhibitors of P97 complex

US-9828363-B2

View Details

Products

Dengue NS1 antigen ELISA kit (96 tests)

NS1 antigen capture ELISA for qualitative detection of dengue NS1 antigen in serum for diagnostic support.

Dengue IgM capture ELISA (96 tests)

Capture ELISA for qualitative detection of anti-dengue IgM antibodies in serum to aid diagnosis of recent infection.

Dengue IgG capture ELISA (96 tests)

Capture ELISA for qualitative detection of anti-dengue IgG antibodies to assist differentiation of primary and secondary infections.

Laboratory reagents and consumables (catalog)

Catalog of antibodies, assay substrates and blockers, controls, enzymes, microplates, conjugates, genomic DNA, tissue slides and other consumables for molecular and protein biology workflows; available via online ordering.


Services

Slide-based online course covering proteomics techniques, mass spectrometry, computational tools, and applications in disease research.

Expertise Areas

  • Small-molecule oncology drug discovery targeting protein homeostasis
  • Medicinal chemistry and compound optimization
  • Target identification and validation for ATPase and metalloprotease families
  • Preclinical oncology models and translational pharmacology
  • Show More (5)

Key Technologies

  • Small-molecule medicinal chemistry
  • Mass spectrometry-based proteomics
  • ELISA and immunoassay formats
  • Western blot and SDS-PAGE
  • Show More (4)

News & Updates

Event listing referencing participation or promotion of a HealthTech summit in 2026.

Course material covering proteomics techniques, mass spectrometry, computational analysis and emerging topics such as single-cell proteomics and AI applications.

Blog article about transcriptomics and gene expression analysis in the post-genomic era.


Similar organizations

Browse all ORGANIZATIONS

JOIN OUR MAILING LIST

Stay Connected with MTEC

Keep up with active and upcoming solicitations, MTEC news and other valuable information.