Chromatan, Inc.


ChromaTan is revolutionizing bioprocessing with continuous chromatography solutions, including the innovative BioRMB™ platform and the Kascade™ system. Their mission is to enhance productivity, product quality, and recovery in biologics manufacturing through column-free, scalable, and efficient purification technologies. They focus on applications for sensitive modalities such as gene therapy, DNA, mRNA, and viral vectors, aiming to simplify validation, reduce operational costs, and enable process intensification for the biopharmaceutical industry.

Industries

biotechnology
health-care
manufacturing
medical

Nr. of Employees

small (1-50)

Chromatan, Inc.

State College, Pennsylvania, United States, North America


Products

Bench-top continuous moving-bed chromatography system with sterile single-use flowpath

A benchtop system designed to perform continuous, column-free purification using a moving resin slurry retained by hollow-fiber membranes. Designed for process development, preclinical runs and GMP manufacturing when used with sterile single-use flowpaths.


Services

Continuous chromatography process development

Process development for continuous moving-bed and countercurrent tangential chromatography methods across capture and polishing steps for biologics and viral vectors.

Equipment supply and GMP-capable system deployment

Provision of bench-scale continuous moving-bed chromatography systems with sterile single-use flowpaths and options for GMP clinical material production.

Controls integration and automation services

Integration of chromatography systems with industrial control platforms and delivery of validated automation solutions, plus on-site and remote training.

Collaborative R&D and sponsored projects

Partnerships, grant-funded projects and collaborative R&D with academic and industry partners to develop continuous purification approaches and analytical integrations.

Expertise Areas

  • Continuous chromatography and moving-bed purification
  • Process intensification and integrated continuous bioprocessing
  • Downstream process development for viral vectors and nucleic acids
  • Single-use sterile flowpath design for GMP manufacturing
  • Show More (7)

Key Technologies

  • Moving-bed / continuous countercurrent tangential chromatography
  • Single-use disposable sterile flowpaths
  • Hollow-fiber membrane retention for slurry systems
  • Vortex-based fluidic separation (Dean-type vortex separators)
  • Show More (6)

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