C&SR
C&SR Inc. develops and supplies humanized (human immune system) rodent models and related preclinical R&D services. The company performs engraftment of human peripheral blood mononuclear cells (PBMC) and human CD34+ hematopoietic stem cells to produce short-term and sustained humanized animal models, applies immune reconstitution/boosting protocols to increase human immune cell chimerism, and offers custom disease-model development and evaluation across oncology (CDX/PDX), infectious, respiratory, metabolic, neurological and autoimmune indications. The organization reports domestic patent registration and multiple research collaborations and MOUs with academic and industry partners.
Industries
Nr. of Employees
small (1-50)
Products
Short-term PBMC-engrafted humanized rodent model
A short-term humanized animal model generated by engrafting human PBMCs for transient evaluation of human immune responses.
Sustained HSC-engrafted humanized rodent model
A long-term humanized animal model produced by transplantation of human CD34+ hematopoietic stem/progenitor cells, designed for extended studies of human hematopoiesis and immunity.
Short-term PBMC-engrafted humanized rodent model
A short-term humanized animal model generated by engrafting human PBMCs for transient evaluation of human immune responses.
Sustained HSC-engrafted humanized rodent model
A long-term humanized animal model produced by transplantation of human CD34+ hematopoietic stem/progenitor cells, designed for extended studies of human hematopoiesis and immunity.
Services
Engineering and validation of short-term PBMC-engrafted and sustained HSC-engrafted humanized rodent models for preclinical research.
Design and delivery of disease-specific models (oncology CDX/PDX, infectious, respiratory, metabolic, neurological, urinary, autoimmune) and associated efficacy testing.
Analytical and functional assessment of candidate therapeutics using humanized animal platforms to support decision-making in drug development.
Advisory services for selecting appropriate models, study design, and operational planning for preclinical programs.
Engineering and validation of short-term PBMC-engrafted and sustained HSC-engrafted humanized rodent models for preclinical research.
Design and delivery of disease-specific models (oncology CDX/PDX, infectious, respiratory, metabolic, neurological, urinary, autoimmune) and associated efficacy testing.
Analytical and functional assessment of candidate therapeutics using humanized animal platforms to support decision-making in drug development.
Advisory services for selecting appropriate models, study design, and operational planning for preclinical programs.
Expertise Areas
- Humanized animal model development
- Preclinical oncology models (CDX/PDX)
- Infectious disease modeling
- Autoimmune and immunology modeling
Key Technologies
- Humanized mouse models (HSC and PBMC engraftment)
- Hematopoietic stem cell (CD34+) transplantation
- PBMC engraftment
- Immune reconstitution / boosting protocols
News & Updates
Report of a strategic MOU between the company and a partner to respond to new regulatory provisions (news listing).
Announcement of a humanized model tailored for systemic lupus erythematosus.
Report of a tripartite MOU to develop and expand the humanized model market.
News item reporting an award for an outstanding patent in biotechnology.
Announcement that research related to humanized models was published in a peer-reviewed international journal.
Registered domestic patent titled relating to human stem cell transplantation and immune boosting-based humanized mouse and its manufacturing method (Korean patent No. 10-2613264).
Report of a strategic MOU between the company and a partner to respond to new regulatory provisions (news listing).
Announcement of a humanized model tailored for systemic lupus erythematosus.
Report of a tripartite MOU to develop and expand the humanized model market.
News item reporting an award for an outstanding patent in biotechnology.
Announcement that research related to humanized models was published in a peer-reviewed international journal.
Registered domestic patent titled relating to human stem cell transplantation and immune boosting-based humanized mouse and its manufacturing method (Korean patent No. 10-2613264).