BUGS Bioscience
BUGS Bioscience is a pioneering company dedicated to molecular surveillance of infectious diseases. It combines molecular biology, advanced mathematics, and software to develop high-throughput, genomics-based tools for pathogen analysis, particularly focusing on pneumococcal serotyping. The company aims to support vaccine development and delivery worldwide, especially in combating diseases like pneumonia, meningitis, and septicaemia caused by Streptococcus pneumoniae. As a spin-out from St George’s, University of London, it reinvests its revenues into further technological development to contribute to global health initiatives.
Industries
BUGS Bioscience
Products
Pneumococcal microarray panel (molecular serotyping)
Microarray panel targeting capsule biosynthesis genes for molecular serotyping of Streptococcus pneumoniae with capacity to detect multiple serotypes and estimate relative abundance.
Group B Streptococcus microarray panel
Microarray panel for serotyping and detection of Group B Streptococcus targets for surveillance and epidemiology.
Haemophilus influenzae microarray panel
Microarray panel for typing Haemophilus influenzae including encapsulated serotypes and non-typeable strains for surveillance applications.
Neisseria meningitidis microarray panel
Microarray panel designed to detect serogroups and relevant markers in Neisseria meningitidis for surveillance and epidemiological typing.
Pneumococcal microarray panel (molecular serotyping)
Microarray panel targeting capsule biosynthesis genes for molecular serotyping of Streptococcus pneumoniae with capacity to detect multiple serotypes and estimate relative abundance.
Group B Streptococcus microarray panel
Microarray panel for serotyping and detection of Group B Streptococcus targets for surveillance and epidemiology.
Haemophilus influenzae microarray panel
Microarray panel for typing Haemophilus influenzae including encapsulated serotypes and non-typeable strains for surveillance applications.
Neisseria meningitidis microarray panel
Microarray panel designed to detect serogroups and relevant markers in Neisseria meningitidis for surveillance and epidemiological typing.
Services
Molecular serotyping laboratory service
Laboratory testing service that determines pathogen serotype(s) from cultured isolates or directly from clinical specimens using microarray-based molecular methods.
Genomic data analysis and reporting service
Bioinformatics analysis and interpretation of genomic assay data, including detection of resistance markers, identification of novel variants, and generation of surveillance reports.
Custom microarray panel design
Design and provision of custom microarray panels for targeted detection of serotypes, resistance markers, or specific pathogen panels.
Software platform development and deployment for surveillance
Design and build of scalable surveillance software including data management, visualization and automated analysis pipelines suitable for field trials and routine surveillance.
Molecular serotyping laboratory service
Laboratory testing service that determines pathogen serotype(s) from cultured isolates or directly from clinical specimens using microarray-based molecular methods.
Genomic data analysis and reporting service
Bioinformatics analysis and interpretation of genomic assay data, including detection of resistance markers, identification of novel variants, and generation of surveillance reports.
Custom microarray panel design
Design and provision of custom microarray panels for targeted detection of serotypes, resistance markers, or specific pathogen panels.
Software platform development and deployment for surveillance
Design and build of scalable surveillance software including data management, visualization and automated analysis pipelines suitable for field trials and routine surveillance.
Expertise Areas
- Molecular serotyping
- Pathogen genomics and genomic epidemiology
- Microarray assay design and deployment
- Clinical sample processing for pathogen detection
Key Technologies
- Microarray-based molecular detection
- Sequence capture / target enrichment
- Targeted probe hybridization
- Comparative genomic hybridization (CGH) / genotyping