BTS Research
BioLegacy Research is a San Diego-based Contract Research Organization providing GLP and Non-GLP preclinical services to clients in pharmaceutical, biopharmaceutical, biotech, academic research, and medical device industries since 2001. They support early discovery in vitro and in vivo programs, mechanism of action studies, efficacy studies in disease models, toxicology, and IND-enabling studies, with expertise in inflammation, oncology, and metabolic diseases. They emphasize regulatory compliance, animal care, and offer state-of-the-art lab space. They also provide specialized services such as SARS-CoV-2 neutralizing antibody assays and advanced molecular imaging.
Industries
Nr. of Employees
small (1-50)
Patents
Products
In Vitro Services
Provides clinical pathology services, bioanalytical for small molecules and biologics, and cell-based functional assays to support pharmaceutical product development.
In Vivo Services
Offers preclinical studies using various animal models to investigate biologics, inflammation, cancer, and metabolic diseases.
SARS-COV-2 NAb Assay
Conducts in-house testing of SARS-COV2 vaccines in animal models to detect the presence of Neutralizing Antibodies (NAbs).
Pharmacology Services
Conducts pharmacokinetic (PK) and pharmacodynamic (PD) studies to evaluate bioavailability, target specificity, and the best route of administration for compounds.
Toxicology Services
Executes acute, subchronic, chronic, and neurotoxicity studies to assess the safety and risk of substances.
Disease Models
Provides validated disease models for various conditions including cancer, inflammation, and metabolic diseases.
In Vitro Services
Provides clinical pathology services, bioanalytical for small molecules and biologics, and cell-based functional assays to support pharmaceutical product development.
In Vivo Services
Offers preclinical studies using various animal models to investigate biologics, inflammation, cancer, and metabolic diseases.
SARS-COV-2 NAb Assay
Conducts in-house testing of SARS-COV2 vaccines in animal models to detect the presence of Neutralizing Antibodies (NAbs).
Pharmacology Services
Conducts pharmacokinetic (PK) and pharmacodynamic (PD) studies to evaluate bioavailability, target specificity, and the best route of administration for compounds.
Toxicology Services
Executes acute, subchronic, chronic, and neurotoxicity studies to assess the safety and risk of substances.
Disease Models
Provides validated disease models for various conditions including cancer, inflammation, and metabolic diseases.
Services
Provision of a broad set of in vitro assays to support discovery, mechanism-of-action studies, assay optimization and to inform in vivo study design.
In vivo pharmacology and efficacy studies to assess efficacy, mechanism-of-action, PK/PD and ADME in disease models across multiple species.
Acute and repeated-dose toxicology studies, including IND-enabling toxicology programs in small and large animals with GLP and non-GLP options.
Support for IND preparation including conduct of IND-enabling studies and regulatory-focused documentation and workflows.
Access to and use of tailored animal disease models for inflammation, oncology, metabolic and other therapeutic areas with disease staging to reduce variability.
Preclinical testing and evaluation services for medical devices including functional performance testing and regulatory-focused assessments.
Provision of a broad set of in vitro assays to support discovery, mechanism-of-action studies, assay optimization and to inform in vivo study design.
In vivo pharmacology and efficacy studies to assess efficacy, mechanism-of-action, PK/PD and ADME in disease models across multiple species.
Acute and repeated-dose toxicology studies, including IND-enabling toxicology programs in small and large animals with GLP and non-GLP options.
Support for IND preparation including conduct of IND-enabling studies and regulatory-focused documentation and workflows.
Access to and use of tailored animal disease models for inflammation, oncology, metabolic and other therapeutic areas with disease staging to reduce variability.
Preclinical testing and evaluation services for medical devices including functional performance testing and regulatory-focused assessments.
Expertise Areas
- Preclinical contract research (CRO) operations
- GLP and non-GLP study execution
- In vitro assay development
- In vivo pharmacology and toxicology
Key Technologies
- Molecular imaging
- SPECT (nuclear medicine imaging)
- Ultrasound imaging with strain analysis
- 3D/4D biodistribution imaging