Boston Childrens Hospital


The Precision Vaccines Program (PVP), based in the Department of Pediatrics at Boston Children’s Hospital, is an academic research initiative dedicated to discovering and developing next-generation vaccines tailored to vulnerable populations. PVP conducts both basic and translational research to create novel vaccines and therapeutics for diseases that disproportionately affect infants, older adults, and immunocompromised individuals. The program brings together experts in vaccinology, clinical trials, immunology, molecular biology, data management, biostatistics, bioinformatics, and systems biology, fostering international collaboration among academia, government, and industry to advance precision medicine in vaccinology.

Industries

N/A

Nr. of Employees

small (1-50)


Patents

Local anesthetics with selective-sensory nerve blockade

US-12454509-B2

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Nanobody based imaging and targeting of ECM in disease and development

US-12454576-B2

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ABCB5 ligands and substrates

US-12448461-B2

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Macromolecular prodrugs for light-emitting diodes and uses thereof

US-12427196-B2

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Methods and compositions to treat and prevent infection

US-12414971-B2

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ApoM-Fc fusion proteins for treating lung diseases

US-12415847-B2

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Services

A membership-based collaborative network that connects academic, government, and industry participants to coordinate and advance vaccine research activities.

Conducts basic and translational studies to develop vaccine and therapeutic candidates tailored to vulnerable populations.

Support for protocol development and implementation of clinical trials for vaccine candidates, with focus on vulnerable populations.

Analytic services including bioinformatics, systems biology analyses, biostatistics, and data management to support vaccine research and trials.

Presentation of research concepts and findings through public talks and multimedia to inform scientific and lay audiences.

Expertise Areas

  • Precision vaccinology
  • Clinical trial management for vaccines
  • Translational vaccine R&D
  • Vaccine immunology
  • Show More (5)

Key Technologies

  • Precision medicine approaches for vaccine design
  • Systems biology
  • Bioinformatics
  • Molecular biology techniques
  • Show More (3)

News & Updates

A TEDxBoston talk by Dr. Ofer Levy discussing innovation in precision vaccines.

A TEDxBoston talk by Dr. Ofer Levy reflecting on lessons learned from the COVID-19 pandemic in the context of precision vaccines.

A TED talk by Dr. Ofer Levy on the science and promise of personalized vaccines.


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