Biotest Facility

A high-multiplex protein biomarker panel designed for immuno-oncology research, enabling simultaneous measurement of 92 protein biomarkers using small sample volumes.

A multiplex protein biomarker panel designed for high-throughput profiling of metabolism-related protein biomarkers.

A protein assay panel designed for multiplex biomarker profiling focused on immune response markers.

A high-multiplex protein biomarker assay panel designed for cardiovascular disease profiling and protein biomarker research.

A protein assay panel designed for multiplex biomarker profiling and development applications.

A protein assay panel designed for high-throughput multiplex biomarker profiling focusing on cardiovascular disease related proteins.

A protein assay panel designed for high-throughput multiplex biomarker profiling focusing on exploratory neurological protein targets using proximity extension assay technology.

A protein assay list and content panel for multiplex biomarker profiling focused on cytokines and chemokines.

Intermediate format assays with modular subpanels of 43 to 92 biomarkers covering 1100+ total biomarkers.

High-throughput multiplex panel allowing the simultaneous analysis of over 5400+ targets using NGS readout with a 2 µL sample volume.

Modular assay with 8 subpanels measuring 2900+ biomarkers.

Comprehensive protein biomarker panel designed to screen large numbers of targets utilizing 6 µL of sample.

High-throughput services in our cell laboratory, providing functional screenings, validation of test compounds on in vitro cell culture, cell expansions, and PBMC isolation from fresh whole blood.

Digital PCR (dPCR) service enabling RNA/DNA quantification with superior accuracy, precision and reproducibility without standard curves.

Sample preparation and high-quality extraction of DNA, RNA, and protein for downstream analysis utilizing automated workflow and robotic pipetting.

Quantitative efficacy studies in mice and rats comparing treatments to control groups to evaluate therapeutic effect and dose-response relationships.

Cost efficient and high-throughput genotyping analyses service based on high-throughput and reproducibility, utilizing technologies such as Fluidigm Biomark HD and NanoString systems.

Proteomics platform to explore from 92 to 3072 proteins.

Preclinical pharmacokinetic and ADME study services utilizing mice and rats to trace drug absorption, distribution, metabolism, and clearance.

Protein quantification services using electrochemiluminescence-based immunoassays from Meso Scale Discovery (MSD) for multiplex protein quantification and biomarker profiling.

Comprehensive miRNA expression services ranging from quantification studies of specific miRNAs to global miRNA expression profiling using advanced technologies.

Meso Scale Discovery assay offering customisable panels of up to 10 markers for quantitative protein analysis.

Fully customizable panels of 15 to 30 markers providing quantitative results for approximately 200 biomarkers.

Absorption, distribution, metabolism, and excretion (ADME) studies designed to evaluate drug behaviour in the body and inform dosing regimens.

The Sciex QTRAP 4500 is a LC-MS/MS system providing high-throughput screening of small molecule drugs and their metabolites with increased quantitative and qualitative sensitivity.

Digital PCR (dPCR) sample analysis service utilizing the QIAcuity system from Qiagen for absolute quantification of target nucleic acid molecules.

Protein analysis platform utilizing electrochemiluminescence detection.

Enzyme-linked immunosorbent assay service for any protein biomarker with quantitative results.

An analysis system offering single molecule detection with no amplification for gene expression profiling, gene fusion, and CNV analysis using unique fluorescent barcodes.

A highly scalable colony management service for mice and rats, ideal for maintaining small-scale backup populations or enabling continuous production and delivery of research animals.

A high-multiplex protein biomarker panel designed for neurology-related studies using proximity extension assay technology.

Structured behavioural observations conducted in mice to assess the impact of substances on neurological and psychological functions.

Small-scale or pilot protein biomarker screening services using Olink Proteomic protein biomarker panels with PEA technology.

Transcriptome profiling by RNAseq of eukaryotic samples offering automated, high-quality, low-cost, stranded library preps with NGS sequencing on the Illumina platform.

Pilot testing service for gene expression studies to select appropriate house-keeping genes and test custom-designed assays.

Specialized techniques for intracerebroventricular dosing and cerebrospinal fluid (CSF) sampling to support CNS-targeted therapies.

High-throughput qPCR system supporting gene expression profiling, SNP genotyping, digital PCR, and mutant detection in nanoscale reactions.

Gene expression analysis platform utilizing digital molecular barcoding technology.

A system enabling high-throughput gene expression analysis in a custom and flexible setup using Integrated Fluidic Circuits (IFC) Chips for low volume reactions.

QIAGEN instrument used for sample extraction and quality control.

QIAGEN instrument used for sample extraction and quality control.

Standard statistical service including testing for normal distribution, cluster analysis, identification of significant differential markers, and Volcano plot generation.

Data analysis utilizing gene set enrichment analysis (GSEA) to determine if classes of genes or proteins are over-represented.

Agilent instrument used for sample extraction and quality control.

Automated system acting as a controller to prepare IFC chips and provide automated library preparation for next-generation sequencing.

Integrated fluidic circuit chip supporting 192 samples and 24 assays.

Data analysis for the visualization of correlation or association among markers in a complex biological system.

Data analysis focused on using clustering methods to gain new knowledge about molecular subgroups or expression patterns.

Data analysis focused on developing a biomarker signature for diagnostics or prognostics using machine learning.

Data analysis utilizing linear mixed effects models to determine the effects of one or more variables of interest for time series data.

Data analysis using survival analysis methods to determine if two different groups of patients have different survival rates.