Bio Detection Systems
BioDetection Systems (BDS) specializes in developing and applying mechanism-based, ultrasensitive, biological monitoring to protect human health and the environment. They offer a range of high-throughput CALUX® reporter assays and complementary technologies for rapid evaluation of toxicity, safety assessments, and identification of beneficial bioactivities. Their mission is to develop and provide innovative bioassays for safety and quality assessment of food, water, environment, consumer products, and chemicals, aiming to replace animal testing with human-relevant in vitro methods. BDS provides services through its own laboratory and under license worldwide, focusing on effect-based bioanalysis for various applications including food safety, water quality, environmental safety, cosmetic safety, and biobased solutions. They are engaged in validation, international guideline incorporation, and promoting regulatory acceptance of their assays.
Industries
Nr. of Employees
small (1-50)
Bio Detection Systems
Amsterdam, Noord-Holland, The Netherlands, Europe
Products
Reporter gene bioassay panels
A suite of cell-based reporter gene assays covering multiple mechanistic endpoints for effect-based screening and quantitative bioactivity profiling.
Reference materials and analytical standards
Analytical standards and reference materials to support calibration, method validation and QA/QC in chemical and bioanalytical testing workflows.
Tissue culture and laboratory consumables
Tissue culture reagents and consumables intended to support reproducible cell-based bioassay workflows.
Extraction and clean-up products
Products and methods for sample extraction and clean-up designed to prepare complex matrices for bioassay and chemical analysis.
Reporter gene bioassay panels
A suite of cell-based reporter gene assays covering multiple mechanistic endpoints for effect-based screening and quantitative bioactivity profiling.
Reference materials and analytical standards
Analytical standards and reference materials to support calibration, method validation and QA/QC in chemical and bioanalytical testing workflows.
Tissue culture and laboratory consumables
Tissue culture reagents and consumables intended to support reproducible cell-based bioassay workflows.
Extraction and clean-up products
Products and methods for sample extraction and clean-up designed to prepare complex matrices for bioassay and chemical analysis.
Services
Effect-based bioanalysis (analytical services)
Provision of high-throughput reporter gene bioassay screening and quantitative effect-based analysis for food, water, environmental and consumer product samples.
Targeted bioanalysis with confirmatory chemistry
Targeted screening workflows combining bioassays with confirmatory chemical analysis for specific regulated compound classes.
Contract research and custom projects
Project-based custom research including discovery, profiling and validation workflows using assay panels and analytical chemistry.
Regulatory and assay integration consultancy
Advisory services for assay selection, interpretation, integration into risk assessment workflows and support for regulatory acceptance efforts.
Accreditation and certification support
Support for assay validation, quality assurance and accreditation (including ISO 17025) to enable routine and regulatory use.
Training and technology licensing
Provision of training programs and licensing agreements for assay implementation and standardized use by external laboratories and partners.
Effect-based bioanalysis (analytical services)
Provision of high-throughput reporter gene bioassay screening and quantitative effect-based analysis for food, water, environmental and consumer product samples.
Targeted bioanalysis with confirmatory chemistry
Targeted screening workflows combining bioassays with confirmatory chemical analysis for specific regulated compound classes.
Contract research and custom projects
Project-based custom research including discovery, profiling and validation workflows using assay panels and analytical chemistry.
Regulatory and assay integration consultancy
Advisory services for assay selection, interpretation, integration into risk assessment workflows and support for regulatory acceptance efforts.
Accreditation and certification support
Support for assay validation, quality assurance and accreditation (including ISO 17025) to enable routine and regulatory use.
Training and technology licensing
Provision of training programs and licensing agreements for assay implementation and standardized use by external laboratories and partners.
Expertise Areas
- In vitro reporter gene bioassay development
- Effect-directed analysis and bioassay-guided fractionation
- Mixture toxicity assessment
- Effect-based environmental and water quality monitoring
Key Technologies
- Cell-based reporter gene assays
- High-throughput bioassay panels
- Effect-directed fractionation workflows
- Gas chromatography–tandem mass spectrometry (GC-MS/MS)