Applied Tissue Technologies
Applied Tissue Technologies LLC, founded in 2000 and headquartered in Hingham, MA, is dedicated to advancing wound healing technologies driven by science. The company focuses on medical innovation, developing proprietary devices and patented treatment methods to improve wound care efficiency globally, including in developing countries. Their research emphasizes Prolonged Field Care and Regenerative Medicine, supported by the US Department of Defense, US Army, Defense Health Agency, and SBIR. They aim to revolutionize negative pressure wound therapy with innovative, foamless, and simplified devices that enable effective treatment and topical delivery of therapeutics.
Industries
Nr. of Employees
small (1-50)
Applied Tissue Technologies
Hingham, Massachusetts, United States, North America
Products
Embossed single-component negative pressure wound dressing
A single-layer, flexible, transparent dressing with embossed microstructures and integrated adhesive rim that distributes negative pressure evenly without separate foam or gauze filler and supports topical delivery of therapeutics.
Sterile micro-autografting kit for minced split-thickness skin grafting
A sterile, hand-powered, single-use kit for harvesting, mechanically preparing, and applying minced split-thickness skin autografts to expand donor site coverage and enable outpatient grafting procedures.
Embossed single-component negative pressure wound dressing
A single-layer, flexible, transparent dressing with embossed microstructures and integrated adhesive rim that distributes negative pressure evenly without separate foam or gauze filler and supports topical delivery of therapeutics.
Sterile micro-autografting kit for minced split-thickness skin grafting
A sterile, hand-powered, single-use kit for harvesting, mechanically preparing, and applying minced split-thickness skin autografts to expand donor site coverage and enable outpatient grafting procedures.
Services
Clinical study sponsorship and execution
Sponsorship and operational support for Phase II studies, randomized controlled trials and case series evaluating wound therapy devices and procedures.
Preclinical study coordination and GLP testing
Design and coordination of GLP preclinical safety and efficacy studies including comparative swine-model testing and topical delivery penetration studies.
Contract manufacturing partnership management
Coordination with exclusive contract manufacturers for sterile single-use device production.
Regulatory and quality system support
Experience obtaining medical device regulatory clearances and maintaining quality management system certifications (e.g., ISO 13485).
Clinical study sponsorship and execution
Sponsorship and operational support for Phase II studies, randomized controlled trials and case series evaluating wound therapy devices and procedures.
Preclinical study coordination and GLP testing
Design and coordination of GLP preclinical safety and efficacy studies including comparative swine-model testing and topical delivery penetration studies.
Contract manufacturing partnership management
Coordination with exclusive contract manufacturers for sterile single-use device production.
Regulatory and quality system support
Experience obtaining medical device regulatory clearances and maintaining quality management system certifications (e.g., ISO 13485).
Expertise Areas
- Negative pressure wound therapy (NPWT) platform development
- Topical drug delivery for wound care
- Micro-autografting and split-thickness skin graft expansion
- Preclinical GLP testing and animal models (swine)
Key Technologies
- Negative pressure wound therapy (NPWT)
- Embossed microstructured single-layer dressings
- Sealed wound microenvironment drug delivery
- Micro-autografting (minced split-thickness skin graft technique)