Apellis Pharmaceuticals, Inc.


Apellis is a biotechnology company dedicated to developing life-changing medicines for challenging diseases by controlling the complement cascade, a part of the immune system. They have pioneered a new class of complement medicine with two approved therapies targeting C3, aiming to transform treatment across a broad range of serious diseases. Their mission is driven by courageous science and compassion, with a focus on innovation, patient advocacy, and corporate responsibility.

Industries

biotechnology
health-care
pharmaceutical
therapeutics

Nr. of Employees

large (251-1000)

Apellis Pharmaceuticals, Inc.

100 5th Avenue, Waltham, MA 02451, USA


Patents

Dosing regimens and related compositions and methods

US-12290566-B2

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RNAS for complement inhibition

US-12251395-B2

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Dosing regimens

US-11903994-B2

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Dosing regimens and related compositions and methods

US-11844841-B2

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Methods of treating chronic disorders with complement inhibitors

US-11712460-B2

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Cell-reactive, long-acting, or targeted compstatin analogs and uses thereof

US-11661441-B2

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Products

Empaveli (pegcetacoplan) injection — subcutaneous formulation

Pegcetacoplan formulated for subcutaneous injection; listed with associated U.S. patents.

Syfovre (pegcetacoplan) injection — intravitreal formulation

Pegcetacoplan formulated for intravitreal injection; listed with associated U.S. patents and described as an approved retinal therapy.


Services

Comprehensive product support for patients and healthcare providers delivered via dedicated websites and phone lines.

Programmatic review and provision of investigational therapy access for individual patients (CU) or groups (EAP) when appropriate and consistent with core principles.

Centralized medical information contact for inquiries and reporting related to therapies.

Expertise Areas

  • Complement therapeutics (C3 targeting)
  • Ophthalmology (retinal disease, geographic atrophy)
  • Rare disease therapeutics
  • Clinical trial management
  • Show More (4)

Key Technologies

  • C3-targeted complement inhibitors
  • Injectable biologic formulations (subcutaneous and intravitreal)
  • Clinical development platforms
  • Patient support and call-center platforms
  • Show More (1)

News & Updates

First-ever therapy for geographic atrophy, a leading cause of blindness

Apellis developed the first therapy targeting C3 for geographic atrophy, marking a significant advancement in treatment for this leading cause of blindness.


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