AmberGen


AmberGen is a Boston-area company founded in 1995, specializing in innovative spatial biology, diagnostics, and therapeutics through patented techniques in proteomics, mass spectrometry, and light-based control of biomolecules. Their mission is to solve key problems in medicine and enable pioneering discoveries in the life sciences.

Industries

Biotechnology
Medical
Medical Device
Biotechnology Research

Nr. of Employees

small (1-50)

AmberGen

Billerica, Massachusetts, United States


Patents

Photocleavable mass-tags for multiplexed mass spectrometric imaging of tissues using biomolecular probes

US-12235277-B2

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Photocleavable mass-tags for multiplexed mass spectrometric imaging of tissues using biomolecular probes

US-12181482-B2

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Photocleavable mass-tags for multiplexed mass spectrometric imaging of tissues using biomolecular probes

US-12181481-B2

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Photocleavable mass-tags for multiplexed mass spectrometric imaging of tissues using biomolecular probes

US-12078639-B2

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Global proteomic screening of random bead arrays using mass spectrometry imaging

US-12013392-B2

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Photocleavable mass-tags for multiplexed mass spectrometric imaging of tissues using biomolecular probes

US-11940447-B2

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Products

Photocleavable mass‑tag tissue probes

Validated tissue probes consisting of antibodies or affinity reagents labeled with photocleavable mass‑tag codes for targeted MALDI‑MS immunohistochemistry imaging.

High‑plex antibody panels for mass‑tag imaging

Predefined antibody panels optimized for ultra‑high‑plex mass‑tag based tissue imaging to accelerate multiomic experiments.

Antibody conjugation kits for photocleavable mass‑tags

Laboratory kits that enable users to label their chosen antibodies with photocleavable mass‑tag codes using a one‑step conjugation reaction and a selection of mass‑tag codes.

Post‑imaging panel definition files for image analysis

Downloadable panel definition files and example datasets for SCiLS Scope/SCiLS Lab (OME‑TIFF) to support post‑imaging antibody assignments and analysis.

Miralys

A high-plex, multiomic and multimodal spatial biology imaging and MALDI-IHC platform designed for cancer research, neurodegenerative diseases, and tissue drug distribution analysis.

Miralys Starter Kit

Comprehensive starter kit including all materials needed to implement the Miralys MALDI HiPLEX-IHC workflow in your lab, complete with validation slides, probe mix, and dedicated technical support.

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Services

End‑to‑end laboratory services for multiomic tissue imaging and analysis, including sample processing, multiplexed mass spectrometry imaging, and delivery of analysis files.

Expertise Areas

  • Spatial biology and mass spectrometry imaging
  • Multiomic tissue imaging (proteins, lipids, glycans, metabolites)
  • Photocleavable reagent chemistry and bioconjugation
  • Proteome‑wide screening and bead‑array proteomics
  • Show More (3)

Key Technologies

  • MALDI mass spectrometry imaging
  • Photocleavable peptide mass‑tags and linkers
  • Photocleavable bead‑array mass spectrometry
  • Antibody conjugation chemistry for mass‑tags
  • Show More (3)

News & Updates

AmberGen received a grant to develop a blood-based Alzheimer Diagnostic Assay based on its proprietary PC-PURE technology.


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