Aeromics, Inc.


Aeromics is a clinical-stage pharmaceutical company focused on developing therapeutics based on a revolutionary understanding of water physiology. Their mission is to control edema by targeting molecular water channels, with the aim of improving patient outcomes in conditions such as stroke, spinal cord injury, CNS surgery, and brain cancer. They are developing an aquaporin-4 inhibitor, AER-271, to prevent or arrest brain swelling following ischemic events, with ongoing clinical trials to evaluate its safety and efficacy.

Industries

biotechnology
life-science
therapeutics

Nr. of Employees

small (1-50)

Aeromics, Inc.

Cleveland, Ohio, United States, North America


Patents

Prodrug salts

US-12213987-B2

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Crystals

US-12091431-B2

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Methods of treating or controlling cytotoxic cerebral edema consequent to an ischemic stroke

US-11873266-B2

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Pharmaceutical compositions and methods of making pharmaceutical compositions comprising 2-{[3,5-bis(trifluoromethyl)phenyl]carbamoyl}-4-chlorophenyl dihydrogen phosphate

US-11801254-B2

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Crystals

US-11725018-B2

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Crystals

US-11117909-B2

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Products

Clinical-stage intravenous inhibitor targeting aquaporin-4

A clinical-stage small-molecule therapeutic candidate formulated for intravenous administration to prevent or reduce cerebral edema after ischemic brain injury.


Services

A formal policy to consider providing investigational therapeutics to eligible patients outside of clinical trials.

Expertise Areas

  • Neurology therapeutics development
  • Cerebral edema and brain swelling therapeutics
  • Small-molecule drug discovery and lead optimization
  • Early-phase clinical trial management (Phase I/II)
  • Show More (3)

Key Technologies

  • Aquaporin-4 targeting
  • Small-molecule high-throughput screening
  • Lead optimization chemistry
  • Intravenous formulation development
  • Show More (3)

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