AbGenics Life Sciences

AbGenics is a biotechnology company focused on the generation of unique antibody libraries, including camelid, mouse, and human antibodies, targeting cancer, immunoinflammation, and infectious pathogens. The company aims to develop novel biologics and diagnostics through proprietary technologies, with a mission to be a global leader in antibody-based solutions for human diseases. Their core values emphasize responsible scientific research, societal impact, and translational development of biologicals.

Industries

Analytics

Biotechnology

Life Science

Research Services

Nr. of Employees

small (1-50)

AbGenics Life Sciences

Pune Division, Maharashtra, India

https://abgenics.in

info@abgenics.in

+91 8669959200

Products

Antibody–antimicrobial peptide fusion candidates (lead series)

Lead biologic candidates combining antibody fragments with antimicrobial peptides designed to neutralize bacterial and fungal pathogens while preserving host microbiota.

Ultra-sensitive pathogen detection assays (prototype)

Prototype immunoassays using pathogen-specific single-domain antibodies aimed at detecting blood-borne pathogens in sepsis patients.

RNAi-based antiparasitic candidates

Preclinical candidate molecules based on RNA interference for control of geohelminth and other parasitic infections.

CaMab

Development of Camelid monoclonal antibody fragments (CaMab/ VHH) based immunotherapeutic molecules for infections, cancers and autoimmune diseases.

CaMab-Drug Combinations

Camelid antibody drug combination and conjugate platform.

RNAi

RNAi therapeutics platform technology.

RNAi technology

RNA interference (RNAi) vectors utilizing probiotic Lactobacilli to target geohelminth parasites in the gut by releasing antiparasitic RNAi molecules.

Mouse scFv Library Generation and Production

Specialized mouse short chain variable fragment (scFv) antibody generation services against client-provided antigens, utilizing immunization, phage display, and affinity chromatography purification.

Anti-cancer scFv Antibody Libraries

Libraries of camelid, mouse, and human scFv antibody fragments developed against common cancers using the phage display system.

Camelid Antibody Library Generation and Production

Specialized camelid antibody generation service against client-provided antigens, utilizing immunized camels and monoclonal antibodies isolated by phage display.

Short chain variable fragments (scFv) from mice and humans

Engineered short chain variable fragments (scFv) sourced from mice and humans.

Human scFv

Human single-chain variable fragment antibody generation service.

Camelid antibodies (CaMab)

Camel derived monoclonal antibodies offered by AbGenics Life Sciences.

Camelids VHH

Camelid VHH nanobody discovery format.

Antibody Affinity Maturation

Antibodies can be affinity matured by chain shuffling for scFv.

ESKAPE CaMabs

Antibodies against serious pathogens like Enterobacter, Streptococcus, Klebsiella, Acinetobacter, Pseudomonas, and Enterococcus for therapy or diagnostic applications.

AbTids

Pathogen specific neutralizing camelid antibodies (VHH/CaMab) combined with potent antimicrobial peptides by a cleavable linker to create AbTids, which rapidly lyse and neutralize pathogens with reduced toxicity and high target specificity.

Heavy chain antibodies derived from camels (VHH)

Engineered heavy chain antibodies derived from camels offering unique properties for different applications.

Anti-Infective Camelid Antibodies and Probiotics Based Delivery Vehicles

Development of anti-infective camelid antibodies and probiotics based delivery vehicles for enteral delivery to human and animals.

Antibody Reformating

Reformatting of VHH or scFv into full-length antibodies or Fab fragments, with options for conjugation and transient expression in mammalian and insect cell lines.

Enteric E coli, Salmonella and Clostridia CaMabs

CaMabs for controlling enteric infections, secreted and surface displayed by gut colonizing Lactobacilli.

Anti-infectives

AbTids - CaMab and Antimicrobial Peptides fusion technology targeting infectious diseases.

Nanobodies for diagnostic applications

Nanobody development services leveraging the small size and extreme stability of camelid antibodies to create highly sensitive assays for detecting pathogens in sepsis patients.

Antifungal CaMabs

Antibodies against Candida, Malassezia, Tricophyton, and Aspergillus for systemic and topical use.

Antibody Modifications

Services for affinity maturation, humanization, solubility enhancement, and conversion of antibodies into bispecific, bivalent, or tetravalent formats.

Unique Engineered Molecules ( AbTids )

Anti-pathogen CaMabs fused with cleavable linkers to antimicrobial or antifungal peptides acting as targeted prodrugs.

Pathogen Specific Camelid Antibodies Diagnostic Assays for Sepsis

Ultra sensitive diagnostic assays using pathogen specific camelid antibodies for the detection of pathogens in the blood of sepsis patients.

Chemi Resistive Biosensor for Sepsis Pathogen Detection

A new assay using pathogen specific camelid antibodies attached to a proprietary graphene based biosensor for specific detection of trace amount of pathogens in the blood of neonates with sepsis.

Anti-Parasitic RNAi Based Molecule

Development of anti-parasitic RNAi based molecule to control human hookworm infections.

Anti-parasitics Probiotic RNAi Therapeutics

Engineered probiotic Lactobacillus containing inhibitory molecules (RNAi) targeting geohelminth parasites in the gut stage of their life cycle.

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Expertise Areas

Antibody discovery and engineering

Single-domain antibody (VHH) development

scFv library construction and screening

Antimicrobial biologics development

Show More (5)

Key Technologies

Single-domain antibody (VHH) platforms

scFv library technologies

Antibody library construction and high-throughput screening

Affinity maturation / lead optimization

Show More (6)

News & Updates

Development of anti-infective camelid antibodies and probiotics based delivery vehicles for enteral delivery to humans and animals.

Development of anti-parasitic RNAi based molecule to control human hookworm infections funded by The Gates Foundation.

Initiation of a project for the development of value added anti-microbials using peptides and camelid antibodies (AbTids), funded by BIRAC, Government of India.

Development of human, mouse, and camelid antibody platforms for rapid identification of leads and novel target ID, and generation of full-length human antibodies against cancer and autoimmune targets.

Establishment of POC for potent antimicrobials and antifungals with MIC range comparable to frontline drugs.

Development of ultra-sensitive diagnostic assays using pathogen-specific camelid antibodies for pathogen detection in sepsis patients, funded by the Gates Foundation.

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AbGenics Life Sciences

Industries

Nr. of Employees

AbGenics Life Sciences

Products

Antibody–antimicrobial peptide fusion candidates (lead series)

Ultra-sensitive pathogen detection assays (prototype)

RNAi-based antiparasitic candidates

CaMab

CaMab-Drug Combinations

RNAi

RNAi technology

Mouse scFv Library Generation and Production

Anti-cancer scFv Antibody Libraries

Camelid Antibody Library Generation and Production

Short chain variable fragments (scFv) from mice and humans

Human scFv

Camelid antibodies (CaMab)

Camelids VHH

Antibody Affinity Maturation

ESKAPE CaMabs

AbTids

Heavy chain antibodies derived from camels (VHH)

Anti-Infective Camelid Antibodies and Probiotics Based Delivery Vehicles

Antibody Reformating

Enteric E coli, Salmonella and Clostridia CaMabs

Anti-infectives

Nanobodies for diagnostic applications

Antifungal CaMabs

Antibody Modifications

Unique Engineered Molecules ( AbTids )

Pathogen Specific Camelid Antibodies Diagnostic Assays for Sepsis

Chemi Resistive Biosensor for Sepsis Pathogen Detection

Anti-Parasitic RNAi Based Molecule

Anti-parasitics Probiotic RNAi Therapeutics

Services

Camelid antibody library generation and production

Mouse scFv library generation and production

Antibody modification services

Nanobodies for diagnostic applications

Expertise Areas

Key Technologies

News & Updates

Development of anti-infective camelid antibodies and probiotics based delivery vehicles for enteral delivery to humans and animals.

Development of anti-parasitic RNAi based molecule to control human hookworm infections funded by The Gates Foundation.

Initiation of a project for the development of value added anti-microbials using peptides and camelid antibodies (AbTids), funded by BIRAC, Government of India.

Development of human, mouse, and camelid antibody platforms for rapid identification of leads and novel target ID, and generation of full-length human antibodies against cancer and autoimmune targets.

Establishment of POC for potent antimicrobials and antifungals with MIC range comparable to frontline drugs.

Development of ultra-sensitive diagnostic assays using pathogen-specific camelid antibodies for pathogen detection in sepsis patients, funded by the Gates Foundation.

Identification of a pathogen target that reverses antimicrobial resistance in P. aeruginosa, involving the C4 decarboxylate transporter.

Development of broad-spectrum AbTids targeting the C4 decarboxylate transporter of ESKAPE pathogens.

Camelid antibodies coupled to nanoparticles for diagnostics and therapeutics for superbugs.

Collaborations with medtech device companies to develop sensitive assays for blood-borne pathogen detection in sepsis and other diseases.

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