3i DIAGNOSTICS
3i Diagnostics is dedicated to developing rapid, affordable, and easy-to-use diagnostic technologies to identify infectious microbes and antimicrobial resistant strains in less than an hour. Their mission is to improve patient outcomes, reduce treatment costs, and combat antibiotic resistance by providing clinicians with timely and precise microbial identification. They are innovating with platforms like Biospectrix™ and developing assays for blood, sputum, urine, and other samples, aiming to revolutionize infection diagnosis and antimicrobial stewardship. The company is also working on launching an RUO contamination detection kit for biologics and is in talks with several companies to use their sample prep technology as a front-end addition to other detection methods, including sequencing, flow cytometry, mass spectrometry, and PCR. They are developing a database of IR signatures for pathogens, with potential to identify specific strains and resistance, focusing initially on prevalent bacterial strains causing sepsis.
Industries
Nr. of Employees
small (1-50)
Products
Sample preparation cartridge for isolating intact microbes from whole blood (RUO)
A research‑use sample preparation cartridge that isolates intact microbial cells from whole blood without antibodies or nucleic‑acid reagents using a selective lysis and filtration module; isolates can be recovered for culture or analyzed directly.
Research‑use contamination screening kit for biologics (planned RUO)
Planned research‑use kit intended for rapid screening of microbial contamination in biologic products and cell culture using intact‑pathogen isolation followed by detection.
Infrared‑based research instrument prototype (RUO)
A research‑use instrument combining the sample‑preparation cartridge with an IR detection module for spectral acquisition and identification; intended for beta testing and database building prior to clinical instrument development.
Sample preparation cartridge for isolating intact microbes from whole blood (RUO)
A research‑use sample preparation cartridge that isolates intact microbial cells from whole blood without antibodies or nucleic‑acid reagents using a selective lysis and filtration module; isolates can be recovered for culture or analyzed directly.
Research‑use contamination screening kit for biologics (planned RUO)
Planned research‑use kit intended for rapid screening of microbial contamination in biologic products and cell culture using intact‑pathogen isolation followed by detection.
Infrared‑based research instrument prototype (RUO)
A research‑use instrument combining the sample‑preparation cartridge with an IR detection module for spectral acquisition and identification; intended for beta testing and database building prior to clinical instrument development.
Services
Collaborative R&D and beta testing partnerships
Partnerships with academic and clinical collaborators to test prototypes, contribute clinical or research samples to reference library development, and validate identification algorithms and workflows.
Clinical validation planning and regulatory submission support
Design of phased clinical study protocols and regulatory engagement strategies to support transition from research‑use workflows to clinical diagnostic instruments, including initial focused organism panels and subsequent database expansion.
Front‑end integration partnerships for analytical platforms
Technical collaboration and integration services to adapt the sample‑preparation fluidics for use as a front end to sequencing, PCR panels, flow cytometry, mass spectrometry, and other downstream detection systems.
Collaborative R&D and beta testing partnerships
Partnerships with academic and clinical collaborators to test prototypes, contribute clinical or research samples to reference library development, and validate identification algorithms and workflows.
Clinical validation planning and regulatory submission support
Design of phased clinical study protocols and regulatory engagement strategies to support transition from research‑use workflows to clinical diagnostic instruments, including initial focused organism panels and subsequent database expansion.
Front‑end integration partnerships for analytical platforms
Technical collaboration and integration services to adapt the sample‑preparation fluidics for use as a front end to sequencing, PCR panels, flow cytometry, mass spectrometry, and other downstream detection systems.
Expertise Areas
- Rapid culture‑independent clinical microbiology
- Microfluidic sample preparation and high‑fold pathogen concentration
- Infrared molecular spectroscopy for microorganism identification
- Spectral database curation and computational pattern matching
Key Technologies
- Microfluidics
- Shear/pressure-driven selective lysis
- Infrared molecular spectroscopy
- IR‑transparent cartridge materials