Intranasal

Intranasal delivery exploits richly vascularized nasal mucosa and direct nose-to-brain pathways (olfactory and trigeminal) to enable rapid systemic and CNS uptake without IV access. It is suitable for emergency analgesics, anticonvulsants, naloxone, and mucosal vaccines; formulation, mucociliary clearance, and deposition determine bioavailability.

Technical Challenges

  • Rapid mucociliary clearance and limited nasal residence time reduce absorption and dose consistency.

  • Inter-individual and situational variability (rhinitis, blood, dehydration, cold environment) alter bioavailability.

  • Restricted deliverable volume and concentration limit dosing for many small-molecule and biologic agents.

  • Formulation-related irritation, local toxicity, and potential for nasal mucosa damage with permeation enhancers.

  • Predictable nose-to-brain targeting and translational models for CNS delivery remain immature.

Emerging Opportunities

  • Device solutions that ensure reproducible deposition in turbinates and olfactory regions under field conditions.

  • Stable, concentrated formulations (liquid and dry powder) that preserve potency, sterility, and tolerability.

  • Safe, effective absorption enhancers or mucoadhesive systems that extend residence time without mucosal injury.

  • Validated preclinical and clinical endpoints for nose-to-brain transport and military-relevant efficacy (e.g., seizure termination, analgesia onset).

  • Scalable manufacturing and cold-chain–resilient products suited to austere logistics and prolonged field care.

Current and Emerging Technologies in Intranasal

Mucosal atomization devices and metered-dose atomizers

Portable atomizers and prefilled metered devices provide consistent droplet size and rapid administration without IV setup, ideal for prehospital and point-of-injury use.

Dry powder intranasal formulations

Stable powders enable thermostable vaccines and biologics, improve shelf life in austere settings, and may enhance uptake to olfactory regions when engineered for particle size and flow.

Mucoadhesive polymers and absorption enhancers

Chitosan derivatives, cellulose ethers, and novel excipients extend residence time and open paracellular pathways to increase bioavailability while maintaining mucosal safety.

Nanoparticle and liposomal carriers for targeted delivery

Nanocarriers can protect labile cargos, permit controlled release, and facilitate trans-epithelial or neuronal transport for CNS-active drugs and vaccines.

Smart devices and sensors for dose confirmation

Integrated dose trackers, Bluetooth-enabled logs, and feedback sensors improve adherence, allow after-action review, and support remote clinical decision-making in distributed care.

Importance to Military Medicine

Rapid, non‑IV intervention at point of injury

Enables immediate administration of lifesaving agents (analgesics, naloxone, anticonvulsants) when IV access is delayed or impossible.

Support for prolonged and austere care

Therapies that are stable at ambient temperatures and do not require infusion pumps reduce logistic burden during extended field care.

Force readiness through mucosal immunization

Nasal vaccines can elicit local mucosal immunity and reduce transmission risk in close-quarter deployments.

Minimized skill requirements for frontline providers

Simplified administration suits medics, corpsmen, and nonmedical responders operating under fire or in remote environments.

Alignment with the MTEC Mission

Accelerates translational pathways from bench to deployed use by combining device, formulation, and clinical expertise in line with MTEC’s DoD-focused mission.

Supports combat casualty care, infectious disease defense, and prolonged/distributed care portfolios prioritized by MTEC.

Enables dual-use solutions that yield civilian public-health benefits while meeting military readiness and austere logistics requirements.

Dual-Use (Military + Civilian) Applications

Prehospital and point-of-injury analgesia, emergency seizure control, opioid overdose reversal, rapid vaccination for outbreak control, and targeted CNS drug delivery for TBI/concussion therapies.

Explore MTEC Members with Intranasal Capabilities

MTEC members—spanning academic formulation scientists, device manufacturers, clinical trialists, and military medical researchers—bring complementary expertise to solve formulation, device, and clinical-validation gaps. Explore member profiles to identify partners with experience in nasal vaccines, dry-powder platforms, atomizer design, and field-testing in austere environments.

80 Members with Intranasal capabilities.

Member
The University of Texas System

The University of Texas System is a leading public university system in the United States, dedicated to improving lives through education, health care, and research. With over 256,000 students enrolled across 14 institutions, the UT System is committed to providing affordable access to higher education and producing a skilled workforce to drive Texas's economy.

Member
Georgia Southern University

Georgia Southern University is a vibrant institution with over 26,100 students across three campuses in Statesboro, Savannah, and Hinesville. The university offers 132 degree programs at the associate, bachelor’s, master’s, and doctorate levels, emphasizing student success, community impact, and research excellence. With a commitment to inclusivity and engagement, Georgia Southern fosters a supportive environment for diverse learners, including military-affiliated and adult students. The university is dedicated to transforming lives through education and community engagement, aligning its programs with regional needs. Additionally, Georgia Southern provides accelerated pathways for students to fast-track their master's degrees, enhancing educational opportunities. The university also emphasizes career readiness and public impact research, preparing students for successful careers and contributing to community development.

Member
FiteBac Pharma

FiteBac Technology/FiteBac Pharma's K21 uniquely targets the underlying disease state, given that most diseases involve microbial-associated inflammation and mitochondrial dysfunction. FiteBac Technology innovations stem from the work of numerous international academic research scientists. FiteBac Pharma K21 is the blockbuster antimicrobial small molecule designed to modulate biological, immunological, and metabolic systems for treating a wide range of infectious and inflammatory diseases. This patented drug substance has demonstrated the ability to safely eliminate bacterial, fungal, and viral infections, enhance innate immunity, induce mitophagy while improving mitochondrial and cellular metabolism, accelerate wound healing, and even promote the development of zebrafish and chickens, leading to increased adult mass. Rigorous research from Dr. Bhupesh Prusty's laboratory and Dr Christopher Rongo's laboratory is focused on various aspects of mitochondrial remodeling and reprograming, as well as mitochondrial-to-nuclear signaling with K21.

Member
The University of Texas at San Antonio

The University of Texas at San Antonio (UTSA) is dedicated to the advancement of knowledge through research, teaching, and community engagement. As a premier public research university, UTSA embraces multicultural traditions and serves as a catalyst for socioeconomic development, providing access to educational excellence and preparing citizen leaders for the global environment.

Member
Auburn University

Auburn University Research & Economic Development is dedicated to advancing research and economic growth through a collaborative effort among its various colleges and departments. The organization focuses on fostering innovation, supporting faculty and student research, and facilitating partnerships with industry and government to address societal challenges and enhance the quality of life. Recent initiatives include the launch of the Team Science Series to promote interdisciplinary collaboration and the development of the Gulf Coast Engineering Research Station to address coastal environmental challenges.

Member
Institute for Integrative & Innovative Research (I³R) at University of Arkansas

The Institute for Integrative & Innovative Research (I³R) at the University of Arkansas is dedicated to pioneering solutions to wicked problems and societal challenges through convergence research. With a mission to advance research excellence and stimulate economic development, I³R focuses on deploying innovations at scale through collaboration across various sectors, including academia, industry, and government.

Member
The University of Texas Medical Branch at Galveston

UTMB is dedicated to supporting research, education, and scholarly endeavors, with a focus on creating the future of healthcare through innovative research and community engagement.

Member
Action Medical Technologies

Action Medical Technologies is a pharmaceutical and medical device company focused on developing innovative solutions that integrate medications with advanced devices and injector systems to improve patient outcomes, particularly in austere prehospital environments.

Member
The University of Chicago

The University of Chicago is a prestigious urban research university committed to rigorous inquiry and intellectual freedom. Founded in 1890, it has produced numerous Nobel laureates and is known for its transformative education and groundbreaking research across various fields. The university fosters an inclusive and diverse learning environment, encouraging participation from all community members.

Member
Memsel

Memsel is a biotechnology research and development company dedicated to enhancing health and combatting infections through advanced phage therapies and targeted delivery systems. The company aims to transform healthcare solutions across human, animal, and plant domains, addressing critical health challenges and antibiotic resistance.

Member
Boston University

Boston University is a major research institution committed to leading breakthroughs across various disciplines. The Office of Research supports and advances research excellence, fostering collaboration among researchers, industry partners, and government leaders to address significant societal challenges.

Member
Baylor University

Baylor University is a preeminent Christian research university committed to addressing the world's most meaningful challenges through top-tier research and scholarship. Recognized as an R1 research institution, Baylor focuses on infusing its distinct Christian mission into its research initiatives, fostering a commitment to excellence and innovation.

Member
Limax Biosciences, Inc.

Limax Biosciences is dedicated to revolutionizing tissue healing through innovative biomaterials inspired by the natural slime of slugs. Their hydrogels provide superior adhesion and healing capabilities, addressing unmet medical needs both inside and outside the body.

Member
The University of Texas at Arlington Research Institute

The UT Arlington Research Institute (UTARI) specializes in applying cutting-edge technologies to real-world engineering problems. Our collaborative endeavors reflect a commitment to excellence, integrity, and respect for all, bringing economic growth and fulfillment to our families, business partners, university, and community.

Member
University of Maryland, Baltimore

The University of Maryland, Baltimore (UMB) is Maryland’s public health, law, and human services university. It is dedicated to improving the human condition and serving the public good through education, research, clinical care, and service. UMB is the founding campus of the University System of Maryland and offers a wide range of professional degrees in health care, human services, and law.

Member
University of North Carolina Wilmington

The University of North Carolina Wilmington (UNCW) is a top doctoral and research institution located in Wilmington, North Carolina. Established in 1947, UNCW has grown to serve nearly 18,000 students and employs about 2,500 staff. The university is dedicated to providing a powerful academic experience that fosters creative inquiry, critical thinking, and thoughtful expression in a beautiful coastal setting. UNCW is committed to educational excellence, community engagement, and global connections, making it a vibrant part of the southeastern North Carolina community. UNCW also emphasizes the importance of freedom of expression and mutual respect within its diverse community.

Member
Keylicon Biosciences

Keylicon Biosciences is developing the next generation of self-amplifying RNA (saRNA) to deliver low-dose, durable vaccines and therapeutics. Our platform produces multivalent vaccines that generate long-lasting immunity from low doses, and can express therapeutic proteins directly within diseased tissues, such as tumors, with high specificity following systemic administration.

Member
University of Missouri-Kansas City

The University of Missouri-Kansas City (UMKC) is dedicated to transforming today's learners into tomorrow's leaders through innovative education, research, and community engagement. With over 125 academic programs, UMKC fosters a diverse and inclusive environment that empowers students to achieve their goals and make a positive impact in their communities.

Member
Mayo Clinic

Mayo Clinic is the largest integrated, not-for-profit medical group practice in the world, dedicated to providing high-quality, patient-centered care. With a history of innovation spanning nearly 150 years, Mayo Clinic is committed to transforming healthcare through research, education, and compassionate care, ensuring that the best possible treatment is available to everyone.

Member
Temple University

Temple University is Philadelphia’s only public university and a global center of academic excellence. It is classified as an R1 institution, indicating very high research activity, and offers over 600 academic programs across 17 diverse schools and colleges. The university is committed to providing accessible education that fosters positive change and prepares students to become leaders in their fields. Additionally, Temple emphasizes a vibrant campus life enriched by arts, culture, and a commitment to diversity and inclusivity. The university also promotes a tobacco-free environment to enhance the health and well-being of its community. Temple's athletics program further enhances student life, with 19 varsity teams competing at the NCAA Division I level, fostering school spirit and community engagement.

Member
University of Kentucky

The Office of Sponsored Projects Administration (OSPA) at the University of Kentucky is dedicated to transforming tomorrow by streamlining grants and contracts. OSPA provides essential services to faculty and staff, including assistance with proposal preparation, award negotiation, and compliance with sponsor policies.

Member
Southwest Research Institute (SwRI)

Southwest Research Institute (SwRI) is a nonprofit research and development organization that provides independent, premier services to government and industry clients. Founded in 1947, SwRI is committed to advancing science and technology to benefit humanity, focusing on innovative solutions that improve human health and safety. With a diverse range of technical divisions, SwRI addresses complex challenges in various fields including mechanical engineering, materials, aerospace, automotive, biomedical, and more.

Member
The University of Texas at Dallas

The University of Texas at Dallas (UT Dallas) is a top public research university located in Richardson, Texas, known for its innovative programs, renowned faculty, and a commitment to academic excellence. With over 31,000 students across seven schools, UT Dallas offers a diverse range of undergraduate and graduate programs designed to prepare students for leadership roles in various fields including science, engineering, business, and the arts. The university emphasizes research, community engagement, and student success, making it a vibrant hub for learning and innovation. Additionally, UT Dallas is recognized for its strong return on investment, high graduation rates, and successful career placement for graduates, with many students continuing their education at prestigious graduate schools.

Member
Nanomedicine Manufacturing Lab, Duquesne University

NANOMEDICINE MANUFACTURING LABORATORY Nanomedicine Manufacturing Laboratory (NML) is a research and development laboratory specializing in nanomaterials and biomaterials for imaging, oxygen delivery, and drug delivery, with a core emphasis on scalable manufacturing and Quality-by-Design (QbD). More informaiton about NML: https://www.duq.edu/research/faculty-research/nanomedicine-lab/nanomed-lab-research.php Led by Dr. Jelena M. Janjic, the Nanomedicine Manufacturing Laboratory develops colloidal nanosystems and implantable biomaterials that support molecular imaging modalities, including magnetic resonance imaging (MRI) and near-infrared fluorescence; biosensing, drug delivery; oxygen delivery; and theranostic nanomaterials, used for local and parenteral administration or as implantable biomaterials. A major barrier to the advancement of nanotechnology-based therapeutics is not conceptual innovation but manufacturability, cost, and quality control. The Nanomedicine Manufacturing Laboratory addresses these challenges by incorporating manufacturing process design, scalability, and quality control at the earliest stages of material design. Over the past decade, the laboratory has established robust, reproducible, and cost-effective nanomedicine manufacturing methods by applying QbD frameworks, enabling reliable scale-up and controlled performance. The laboratory’s work is supported by the U.S. Air Force, the Congressionally Directed Medical Research Programs (CDMRP), and ARPA-H through collaborative programs spanning academia, industry, and government. The Nanomedicine Manufacturing Laboratory operates at the intersection of materials science, manufacturing, and translational medicine, with a focus on developing innovative nanomedicines and biomaterials that translate into accessible, cost-effective future treatments for civilian and military medical needs.

Member
University of Arizona Applied Research Corporation (UA-ARC)

The University of Arizona Applied Research Corporation (UA-ARC) is a non-profit organization affiliated with the University of Arizona, dedicated to leveraging the university's strengths in research and education to address national security challenges. UA-ARC aims to deliver innovative solutions and foster collaborations between academia, industry, and government.

Member
Lumen Bioscience, Inc.

Lumen Bioscience is dedicated to unlocking the full potential of biologic drugs by transforming their development, cost, and accessibility. Utilizing patented technology, Lumen aims to develop biologic drugs faster, safer, and more effectively than traditional methods, addressing diseases that have been neglected by conventional drug-making tools.

Member
University of Utah

The University of Utah (UU) is a leading research institution recognized for its research activity and commitment to innovation and discovery. As an R1 Institution, it is dedicated to advancing knowledge and solving critical problems that challenge our national security interests and impact the global community. We foster interdisciplinary collaboration and provide resources to drive transformative research focused on enhancing medical care superiority for the U.S. Department of Defense (DoD) through advanced medical and engineering research sponsored by our Applied Medical & Engineering Laboratory (AM&E Lab). As a leading public university, UU also provides healthcare services to seven states in the Intermountain West, with the largest catchment of remote and austere frontier territory for any academic center. Leveraging its geographic advantage, technological and commercialization strengths, expertise in medical services, and leading-edge, core engineering competencies, UU is uniquely positioned to address the nation's critical national security interests.

Member
George Mason University

The Institute for Biohealth Innovation (IBI) at George Mason University unites over 300 faculty and thousands of students across 34 departments to advance human health and well-being through innovative research. The IBI focuses on major health challenges, including infectious diseases, cancer, brain and behavior, and cardiovascular health, collaborating with national and international partners to implement solutions that enhance health outcomes.

Member
University of Minnesota

The University of Minnesota's Research and Innovation Office (RIO) serves as a central resource for conducting, managing, and sponsoring research. It aims to facilitate collaborative research that addresses complex problems and promotes innovations that improve lives. RIO oversees research compliance and administration, fostering a culture of integrity and ethical practices in research. Additionally, RIO is committed to enhancing research capacity through various funding opportunities and strategic initiatives, including the management of specialized facilities for biocontainment research.

Member
University of Notre Dame

The University of Notre Dame, founded in 1842, is a prestigious Catholic research university located in South Bend, Indiana. It is dedicated to providing a holistic education that integrates faith, reason, and service to others. The university aims to be a leading global Catholic research institution, fostering a community of scholars committed to inquiry, justice, and the common good.

Member
New York University

New York University (NYU) is a global university that connects talented and ambitious individuals in some of the world's greatest cities. Its mission is to be a top-quality institution, providing a diverse range of academic programs and opportunities for students to engage with the world's challenges. NYU is committed to fostering innovation and entrepreneurship, and it emphasizes diversity, equity, and inclusion in its educational mission. Founded in 1831, NYU has evolved to become a leader in higher education, with a commitment to accessibility and a diverse student body. NYU offers a wide array of academic programs, including accelerated studies and online education, catering to the needs of a global student population.

Member
Northwestern University

Northwestern University is a prestigious institution dedicated to fostering a diverse and inclusive environment, promoting academic excellence, and engaging in impactful research. With campuses in Evanston, Chicago, and Doha, Qatar, Northwestern emphasizes global engagement and community involvement, preparing students to tackle complex challenges through interdisciplinary collaboration and innovative thinking.

Member
The University of Iowa

The University of Iowa is dedicated to providing a comprehensive educational experience that fosters academic excellence, research opportunities, and a vibrant student life. With a commitment to accessibility and inclusivity, the university aims to prepare its students for success in various fields while promoting a supportive community.

Member
Case Western Reserve University

Case Western Reserve University is dedicated to solving the biggest issues of today and tomorrow through innovative research and education. With a commitment to experiential learning, the university offers a wide range of programs and opportunities for students to engage in research, internships, and community service, all within a vibrant campus located in Cleveland, Ohio.

Member
University of Alaska Fairbanks

The University of Alaska Fairbanks (UAF) is a Land, Sea, and Space Grant university and an international center for research, education, and the arts, emphasizing the circumpolar North and its diverse peoples. UAF integrates teaching, research, and public service as it educates students for active citizenship and prepares them for lifelong learning and careers.

Member
University of South Florida

The University of South Florida (USF) is a Preeminent Research University and member of the Association of American Universities (AAU), dedicated to empowering students to maximize their potential for lifelong success. With campuses across the vibrant Tampa Bay region, USF serves nearly 50,000 students and offers a wide range of academic programs, innovative research opportunities, and a commitment to community engagement.

Member
New Jersey Institute of Technology

New Jersey Institute of Technology (NJIT) is a leading public research university dedicated to providing students with a world-class education in STEM fields and beyond. With a commitment to academic excellence, NJIT prepares students to be leaders in the most in-demand fields through innovative programs, expert faculty, and extensive research opportunities. NJIT is recognized for its affordability and return on investment, making it a top choice for students seeking a quality education. NJIT is also ranked among the top public universities in the nation, known for its diverse student body and commitment to fostering an inclusive environment.

Member
Inhalon Biopharma

Inhalon Biopharma is a clinical-stage biotechnology company focused on developing innovative inhaled antibody treatments for acute respiratory infections. Their mission is to provide effective and convenient treatment options for conditions such as RSV, hMPV, influenza, and SARS-CoV-2, utilizing a unique 'test-to-treat' model that enhances patient care.

Member
ClearCure Biosciences

ClearCure Biosciences is a clinical-stage biopharmaceutical company focused on developing non-toxic, first-in-class and best-in-class therapies for cancer, infectious diseases, sepsis, neurological diseases, and cardiovascular conditions. The company emphasizes drugging challenging targets, leveraging proprietary small molecules, nanotechnology, new oncology cell therapies, new transdermal drug delivery technology, AI and omics-driven approaches, and digital health solutions to address serious unmet medical needs. The company is currently seeking collaborators and partnerships.

Member
University of Arkansas for Medical Sciences Office of Research and Sponsored Programs

The University of Arkansas for Medical Sciences Office of Research and Sponsored Programs (ORSP) is dedicated to supporting UAMS faculty in acquiring, performing, and administering projects funded by external sources. The ORSP ensures compliance with policies, negotiates award terms, liaises between investigators and sponsors, and manages subcontracts.

Member
Bexson Biomedical

Bexson Biomedical develops precision-driven therapies for central nervous system (CNS) disorders, focusing on pain and mental health. The company is advancing a pipeline of subcutaneous drug formulations, led by an IND-ready ketamine compound for moderate/severe acute pain. Bexson also develops wearable, programmable delivery devices to enable controlled, scalable drug administration both in clinical and field settings. Their technology targets unmet needs in pain management, neuropsychiatric conditions, and military medicine.

Member
The University of Virginia

Founded by Thomas Jefferson in 1819, the University of Virginia is a prestigious public university that emphasizes the advancement of human knowledge, education of leaders, and cultivation of an informed citizenry. It is recognized for its commitment to academic excellence, vibrant student life, and a strong alumni network, making it one of the top public universities in the United States.

Member
University of Missouri

The University of Missouri is dedicated to advancing research, innovation, and impact through a comprehensive support system for faculty, students, and staff. It aims to foster collaboration, enhance economic development, and promote entrepreneurship, while ensuring compliance with research regulations and ethical standards. The university also emphasizes the importance of interdisciplinary partnerships and provides resources to support veteran entrepreneurs through programs like the Entrepreneurship Bootcamp for Veterans.

Member
University of Massachusetts Lowell

The University of Massachusetts Lowell (UML) is dedicated to providing a comprehensive educational experience that prepares students for success in their careers and lives. With over 200 degree programs and a commitment to research and community engagement, UML fosters a vibrant learning environment for its diverse student body.

Member
University of Nebraska Medical Center

The University of Nebraska Medical Center (UNMC) is dedicated to transforming lives through premier educational programs, innovative research, and extraordinary patient care. Founded in 1869, UNMC is a leader in health sciences education and research, serving as a vital resource for Nebraska and beyond.

Member
University of Georgia

The University of Georgia (UGA) is dedicated to facilitating instruction, scholarly and creative activity, and research collaborations across disciplines. UGA is a leader in research-based products and innovation, significantly impacting the state of Georgia and beyond through its extensive research initiatives and academic programs.

Member
MassBiologics

MassBiologics, part of UMass Chan Medical School, is the only nonprofit, FDA-licensed manufacturer of vaccines and biologics in the United States. With over 100 years of experience, it is dedicated to improving public health through the research, development, and production of biologic products, including vaccines and monoclonal antibodies.

Member
Medical University of South Carolina

The Medical University of South Carolina (MUSC) is South Carolina’s premier biomedical research institution, dedicated to advancing health through innovative research, education, and clinical care. With over $300 million in research funding and a commitment to addressing pressing health challenges, MUSC fosters collaboration among faculty, staff, and community partners to translate scientific discoveries into impactful health solutions. The South Carolina Clinical & Translational Research Institute (SCTR) at MUSC supports innovative research across the translational spectrum, from basic science to population health, including patient-centered and community-engaged research.

Member
University of Florida

The University of Florida is a leading public university that fosters innovation, education, and research. With a commitment to excellence, the university provides a diverse and inclusive environment for students, faculty, and staff, driving impactful discoveries and community engagement.

Member
University of California, Irvine

The UCI Office of Research is dedicated to supporting and enhancing the creative and scholarly activities of UCI faculty and researchers. It provides central administrative support for research programs, ensuring compliance with regulations and fostering an environment conducive to research and innovation.

Member
CMC Pharmaceuticals, Inc.

CMC Pharmaceuticals, Inc. provides integrated services supporting drug development for small molecule therapeutics and medical countermeasures. The company offers comprehensive solutions for formulation and process development, analytical method validation, stability and compatibility testing, manufacturing oversight, and regulatory support across all phases—including specialized expertise in handling highly potent compounds and government MCM (Medical Countermeasure) programs. In-house laboratories and robust regulatory systems ensure submission-ready, compliant data, addressing the safety and operational requirements of both commercial and defense sectors.

Member
Virginia Polytechnic Institute

Virginia Tech is a leading research institution dedicated to improving the quality of life and the human condition through education, research, and community engagement. With a commitment to its motto, 'Ut Prosim' (That I May Serve), Virginia Tech fosters a collaborative environment that integrates technology into all disciplines, preparing scholars to be leaders and problem-solvers.

Member
Louisiana State University Health Sciences Center New Orleans

LSU Health Sciences Center New Orleans is dedicated to educating future health professionals and scientists, advancing research, and providing exceptional healthcare. With six professional schools and numerous affiliated hospitals, LSUHSC-NO aims to improve health outcomes and address health equity challenges in Louisiana.

Member
The University of Texas Permian Basin

The University of Texas Permian Basin (UTPB) offers a modern, affordable education in the heart of West Texas, focusing on student success and community impact. With a commitment to providing a diverse range of undergraduate and graduate programs, UTPB aims to empower students to achieve their academic and career goals while contributing positively to the region. UTPB also emphasizes professional development through innovative programs like the Coursera Career Academy and the Impact Behavioral Health Scholarship, which covers tuition and fees for graduate students in specific programs.

Member
Kindeva Drug Delivery

Kindeva Drug Delivery is a contract development and manufacturing organization specializing in advanced drug delivery systems including pulmonary, nasal, injectable, transdermal, and intradermal therapies. Services range from formulation and analytical development to commercial-scale, Annex 1-compliant GMP manufacturing across global facilities. The company brings integrated expertise in regulatory strategy, device engineering, process and technology transfer, and quality assurance, with a focus on sustainable solutions such as low-GWP propellants and microneedle patch platforms. Kindeva supports complex, patient-centric, and environmentally optimized therapies from product conception through commercialization.

Member
Northeastern University

Northeastern University is a global research university founded in 1898, renowned for its experiential learning model, high-impact research, and deep partnerships. The university emphasizes innovative teaching and research that engage students, faculty, and alumni in solving real-world problems, fostering a dynamic and inclusive community across its 13 campuses worldwide.

Member
University of Montana

The University of Montana (UM) is a flagship public research university located in Missoula, Montana. Established in 1893, UM offers a wide range of undergraduate and graduate programs, emphasizing research, creativity, and community engagement. With a commitment to academic excellence and public service, UM aims to transform lives through education and research, fostering a diverse and inclusive environment for its students.

Member
CMTx Biotech, Inc.

CMTx Biotech, Inc. is an emerging biopharmaceutical company working to develop and commercialize host-directed therapeutics for the treatment of inflammatory and infectious diseases, as well as threat-agnostic medical countermeasures against high-priority chemical, biological, radiological and nuclear (CBRN) threats to homeland security and national defense. Our lead drug candidate is a clinically-tested, highly-stable, orally-administered small molecule that has been shown to improve survival and prevent lung injury in a wide variety of animal models of sepsis, acute respiratory distress syndrome (ARDS) and multiple organ dysfunction syndrome (MODS) across several species, including mice, rats, hamsters, pigs and sheep. Having already secured approximately $4M in funding to-date, including $3.6M in NIH SBIR/STTR grants, we are actively seeking non-dilutive funding, private investment capital and/or an established strategic partner to help advance human clinical trials and FDA Animal Rule development, as well as to expand our product pipeline.

Member
University at Buffalo (UB)

The University at Buffalo is a leading public research university and flagship of the SUNY System, recognized for its innovative research and commitment to societal impact. It aims to transform scientific and technological breakthroughs into global impact, addressing complex challenges through interdisciplinary collaboration.

Member
University of California San Francisco

UC San Francisco is a leading university dedicated to advancing health worldwide through preeminent biomedical research, graduate-level education in the life sciences and health professions, and excellence in patient care. With a commitment to public service, UCSF aims to innovate health care approaches for vulnerable populations and train the next generation of health professionals.

Member
University of Texas Health Houston

UTHealth Houston is Texas’ resource for health care education, innovation, scientific discovery, and excellence in patient care. Since 1972, UTHealth Houston has been dedicated to educating the next generation of health care professionals, advancing biomedical research and public health, and providing exceptional care to communities. With half a century of experience, it is one of the nation’s most comprehensive academic health centers, committed to advancing the quality of human life through education, research, and clinical practice.

Member
SUNY Upstate Medical University

SUNY Upstate Medical University is a leading academic medical center in Central New York, dedicated to providing exceptional patient care, advancing medical research, and educating future healthcare professionals. As the region's only Level I trauma center and a Magnet recognized institution, Upstate is committed to delivering cutting-edge, life-saving treatments and fostering a compassionate, patient-centered environment. The university also plays a significant role in the community through outreach programs and is recognized as one of America's best large employers by Forbes.

Member
Washington State University

Washington State University (WSU) is a public research university dedicated to improving lives by serving the public good. With a commitment to unlocking possibilities, WSU empowers students, faculty, and others to create a world where all people can thrive. The university offers a diverse range of academic programs across its six campuses and is recognized for its high research activity and community engagement.

Member
Northstar Emergency Management, LLC

Northstar owns IP around the use of antibody fragments and nucleic acids to rapidly diagnose and treat bacterial and viral infections. With numerous applications to sepsis and bioterrorism countermeasure, Northstar seeks partnerships with other forward thinking companies and government entities to protect our military and enhance homeland security.

Member
University of California, Los Angeles

UCLA is a leading public research university located in Los Angeles, California. It is renowned for its commitment to the creation, dissemination, preservation, and application of knowledge for the advancement of global society. With a rich history of academic and athletic excellence, UCLA offers a comprehensive environment that supports both academic and personal growth. The university is dedicated to fostering innovation and making a significant impact on the world through groundbreaking research and transformative practices.

Member
Arizona State University

Arizona State University (ASU) is a comprehensive public research university known for its commitment to inclusivity, excellence, and societal impact. ASU is dedicated to advancing research-based solutions for global challenges, fostering strong leadership, and providing quality education accessible to all learners. The university is recognized for its innovative approach to education and its efforts in sustainability, research, and community service. ASU exemplifies a new prototype for the American public research university, focusing on excellence, broad access to quality education, and meaningful societal impact.

Member
Vanderbilt University School of Engineering

The Vanderbilt School of Engineering is a globally recognized academic and research institution dedicated to producing leaders and innovators in engineering. With a commitment to solving grand challenges, the school offers a diverse range of undergraduate and graduate programs across multiple engineering disciplines, fostering a culture of collaboration and excellence.

Member
Medical College of Wisconsin

The Medical College of Wisconsin (MCW) is dedicated to transforming healthcare through innovative education, research, and patient care. With a focus on academic medicine, MCW aims to improve the health of communities by fostering a collaborative learning environment that integrates medical education with groundbreaking research and comprehensive patient care.

Member
University of Texas Health San Antonio

UT Health San Antonio is dedicated to educating the next generation of health care professionals, conducting innovative research, and providing high-quality patient care. With a commitment to community service, the institution aims to improve health outcomes in South Texas and beyond through its six schools and numerous degree programs.

Member
Transforma Bio

TransformaBio, Inc. (formerly known as Nano PharmaSolutions) is a clinical-stage biotechnology company developing innovative drug delivery technologies through its proprietary NanoTransformer® platform. The company's solvent-free, scalable nanotechnology enables targeted delivery of challenging drug molecules for oral, intranasal, topical, and biomaterial applications. TransformaBio is advancing programs in neurotrauma, neurodegenerative disease, dermatology, and regenerative medicine, including the development of an intranasal neuroprotective therapy for traumatic brain injury with potential battlefield applications. The company partners with government, academic, and industry organizations to accelerate innovative medical solutions for both military and civilian patients. The migration of the website from Nanopharmasolutions.com to its new website transformabio.com will be in August 2026.

Member
Indiana University

Indiana University is dedicated to building a better future through education, research, and community engagement. With a commitment to academic excellence, IU offers a diverse range of programs across its nine campuses, fostering an inclusive environment for over 90,000 students from around the world. IU is also at the forefront of groundbreaking research, particularly in areas such as brain health and Alzheimer's disease.

Member
MyFitStrip LLC

MyFitStrip is a precision wellness platform advancing oral and metabolic health by restoring nitric oxide (NO) bioavailability through clinically grounded, microbiome-directed interventions. Built on validated nitrate–nitrite–NO biology, MyFitStrip uses topical oral delivery (chewing gums and lozenges) to enhance nitric oxide production directly within the oral microbiome—supporting beneficial bacteria (e.g., Neisseria, Rothia, Veillonella) while suppressing pathogenic species linked to inflammation, caries, and infection risk. This approach targets a critical physiological pathway, with evidence linking nitric oxide to vascular function, immune defense, and metabolic health, including improvements in endothelial function, blood pressure regulation, antimicrobial activity, and oral pH balance. The platform is complemented by rapid saliva-based test strips that measure nitric oxide status, pH, and uric acid—creating a closed-loop system that drives personalization, compliance, and real-time lifestyle feedback. MyFitStrip’s product suite includes prebiotic chewing gums, slow-release lozenges, and diagnostic strips, all supported by a portfolio of nitric oxide–related patents and a deep body of clinical and scientific research spanning immunology, cardiovascular health, and microbiome science. MyFitStrip is defining a new category at the intersection of oral microbiome modulation and nitric oxide biology, enabling scalable, non-invasive solutions for oral-systemic health optimization.

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The University of Texas Southwestern Medical Center

UT Southwestern Medical Center is a premier academic medical institution dedicated to advancing medical science and improving health care through excellence in education, research, and patient care. The center is renowned for its collaborative environment that fosters innovation and discovery, housing distinguished faculty including Nobel Laureates. UT Southwestern is recognized for its groundbreaking research, comprehensive educational programs, and commitment to patient care, serving millions annually across its facilities.

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Yale University

Yale University, founded in 1701, is dedicated to expanding and sharing knowledge, inspiring innovation, and preserving cultural and scientific information for future generations. It engages with local and global communities to promote cultural understanding and improve the human condition.

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Stanford University

Stanford University, founded nearly 150 years ago, is dedicated to educating students for lives of leadership and contribution with integrity. The university emphasizes advancing fundamental knowledge, cultivating creativity, and pioneering research for effective clinical therapies, while also focusing on societal impact and solutions.

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The University of Tennessee, Knoxville

The University of Tennessee, Knoxville is dedicated to advancing knowledge and understanding through research, scholarship, and creative work. The Office of Research, Innovation, and Economic Development supports faculty, staff, and students in developing competitive proposals and fostering a strong culture of research integrity, aiming to create a more just, prosperous, and sustainable world.

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University of California, Davis

UC Davis, founded in 1908, is a top-tier public university located in California, known for its commitment to education, research, and public service. It offers a diverse range of academic programs and is recognized for its contributions to agriculture, veterinary medicine, and sustainability. The university fosters a collaborative environment that encourages innovation and inclusivity, aiming to enhance the lives of its students and the broader community. Additionally, UC Davis is strategically located in the heart of Northern California, providing easy access to major attractions, including beaches, wine country, and national parks.

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ExiVex Biopharma, Inc.

ExiVex Biopharma, Inc. develops emergency-grade intranasal drug delivery systems for rapid administration of critical medications in central nervous system (CNS) emergencies. The company’s proprietary dual-chamber intranasal platform is designed to deliver bioavailability close to intravenous administration, without needles and requiring no medical training. Their lead program aims to address urgent therapeutic needs in opioid overdose, seizures, migraines, and similar acute CNS events, with a focus on regulatory efficiency and manufacturing scalability.

Member
University of Pittsburgh

The Center for Military Medicine Research (CMMR) at the University of Pittsburgh is dedicated to advancing medical research for wounded service members and their families. The center focuses on trauma, emergency, and critical care, leveraging the university's strengths in medical and engineering fields, and collaborating with Carnegie Mellon University's robotics and AI expertise. CMMR aims to enhance trauma care for warfighters and civilians, contributing to the defense innovation economy.

Member
Texas A&M Engineering Experiment Station (TEES)

The Texas A&M Engineering Experiment Station (TEES) is a state agency and part of the Texas A&M University System, dedicated to improving lives through engineering research, workforce development, and technology transition. TEES collaborates with industry, academia, and government to provide innovative solutions to global technical challenges.

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NIRSense

Rugged Physiological Monitoring for the Modern Warfighter: NIRSense

Under MTEC-21-10-NavyMultiTopic, NIRSense is advancing its tactical jet physiological monitoring technology for broader Navy applications. The project focuses on ruggedized, wireless physiological sensors that can provide reliable, real-time insight into warfighter health and performance in demanding operational environments.

Safi Biotherapeutics

Next-Generation Manufactured Red Blood Cells for Extended Battlefield Blood Supply: Safi Biotherapeutics

Safi Biotherapeutics is developing manufactured red blood cells (mRBCs) with extended shelf life to improve battlefield transfusion readiness and emergency trauma care.

Non-Invasive Glymphatic (GF) Monitoring and Recovery Optimization for Warfighter Cognitive Readiness

Applied Cognition is developing non-invasive glymphatic monitoring and recovery technologies to enhance warfighter cognitive readiness, resilience, and sleep recovery.

Moberg Analytics

Moberg Analytics – Advanced Brain Monitoring & Critical Care Informatic

Moberg’s platform unifies brain monitoring data for faster, precise treatment of severe brain injuries in military and civilian care.

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