Infectious Diseases

Infectious Diseases research for military medicine focuses on rapid point-of-care and field-deployable molecular diagnostics, advanced vaccines and therapeutics, antimicrobial stewardship to counter resistance, and environmental surveillance to detect outbreaks. Work addresses biofilms, wound infections in polytrauma, vector-borne pathogens, and prolonged-field-care constraints.

Technical Challenges

  • Rapid, reliable diagnostics that function in austere, low-power, delayed-evacuation settings

  • Antimicrobial resistance (AMR) and limited new classes of antibiotics for combat-related infections

  • Complex wound biofilms and polymicrobial infections complicating polytrauma and blast injuries

  • Real-time surveillance and outbreak detection across dispersed, deployed forces

Emerging Opportunities

  • Portable molecular and phenotypic diagnostics that detect pathogens and resistance markers at point-of-care

  • Thermostable, quickly manufacturable vaccines and broadly protective therapeutics for emergent threats

  • Novel anti-biofilm and host-directed therapies tailored for contaminated wound care

  • Integrated, secure surveillance platforms with rapid data sharing and decision-support for forward units

Current and Emerging Technologies in Infectious Diseases

Point-of-care molecular and CRISPR diagnostics

Isothermal amplification, CRISPR-based detection, and compact PCR instruments enable rapid identification of pathogens and resistance markers with minimal sample prep for field deployment.

Wearable biosensors and environmental surveillance

Physiologic monitors, airborne sensors, VOC detectors, and wastewater/vector monitoring extend early warning capabilities for outbreaks and individual infection signatures.

Vaccine platforms and adjuvant technologies

mRNA, viral vectors, nanoparticle carriers, and thermostable formulations support rapid design, scalable manufacture, and improved durability for deployment and mass prophylaxis.

Antimicrobial innovations and anti-biofilm strategies

Phage therapy, antimicrobial peptides, biofilm-disrupting agents, and host-directed therapies offer alternatives to classical antibiotics for combat wound infections and AMR pathogens.

Portable sequencing and genomic surveillance

Field-capable sequencers and metagenomic pipelines enable real-time phylogenetics, resistance profiling, and source attribution during outbreaks and complex infections.

AI-driven analytics and decision support

Machine learning augments diagnostics, predicts outbreak trajectories, optimizes antimicrobial selection, and supports logistics and prolonged-field-care clinical decisions.

Importance to Military Medicine

Preserve force readiness

Prevent infectious outbreaks and ensure deployable units remain mission-capable.

Enable prolonged and austere care

Field-ready diagnostics and therapies reduce evacuation needs and improve outcomes during delayed care.

Mitigate combat-related infection morbidity

Target wound biofilms and polymicrobial infections that complicate polytrauma and blast injuries.

Counter biological threats and outbreaks

Rapid detection, vaccines, and therapeutics are essential for biodefense and public health security.

Alignment with the MTEC Mission

Accelerates transition of field-ready diagnostics, vaccines, and antimicrobials to operational use; enables dual-use civilian benefits; leverages multidisciplinary consortia for rapid prototyping; focuses on military-defined requirements and scalable manufacturing.

Dual-Use (Military + Civilian) Applications

Dual-use applications include outbreak response and public-health surveillance, hospital and wound infection control, accelerated vaccine and therapeutic development for civilians, and environmental surveillance for communities and deployed forces.

Explore MTEC Members with Infectious Diseases Capabilities

MTEC members bring interdisciplinary strengths—clinical researchers, diagnostics developers, vaccine manufacturers, bioinformatics and systems-engineering teams—plus streamlined DoD-friendly contracting to accelerate transition. Members provide prototype testing in relevant environments, manufacturing scale-up partnerships, and subject-matter expertise in military operational requirements. Explore member profiles to identify partners with capabilities in rapid diagnostics, AMR solutions, vaccine platforms, and field-deployable surveillance.

195 Members with Infectious Diseases capabilities.

Member
The University of Texas System

The University of Texas System is a leading public university system in the United States, dedicated to improving lives through education, health care, and research. With over 256,000 students enrolled across 14 institutions, the UT System is committed to providing affordable access to higher education and producing a skilled workforce to drive Texas's economy.

Member
IQVIA

IQVIA is a global leader in advanced analytics, technology solutions, and clinical research services for the life sciences industry. With a mission to accelerate innovation for a healthier world and a vision to power smarter healthcare for everyone, everywhere, IQVIA leverages unparalleled data, transformative technology, and deep healthcare expertise to drive better patient outcomes. Operating in over 100 countries with approximately 88,000 employees, IQVIA supports pharmaceutical, biotech, medtech, public health, and government organizations with a comprehensive portfolio of services and solutions. The company is recognized for its Connected Intelligence™, healthcare-grade AI, and commitment to sustainability, innovation, and evidence-based insights that shape the future of healthcare globally. IQVIA is also dedicated to reducing health inequities and driving sustainable change through innovation, collaboration, and data-driven solutions, partnering with organizations worldwide to address complex healthcare challenges.

Member
Georgia Southern University

Georgia Southern University is a vibrant institution with over 26,100 students across three campuses in Statesboro, Savannah, and Hinesville. The university offers 132 degree programs at the associate, bachelor’s, master’s, and doctorate levels, emphasizing student success, community impact, and research excellence. With a commitment to inclusivity and engagement, Georgia Southern fosters a supportive environment for diverse learners, including military-affiliated and adult students. The university is dedicated to transforming lives through education and community engagement, aligning its programs with regional needs. Additionally, Georgia Southern provides accelerated pathways for students to fast-track their master's degrees, enhancing educational opportunities. The university also emphasizes career readiness and public impact research, preparing students for successful careers and contributing to community development.

Member
Volatylix, Inc

Volatylix, a Cambridge, MA based startup, is dedicated to early diagnosis enabling timely and appropriate treatment benefiting the patient, physician, provider and payor. Our patent pending platform – DECIPHER – and unique detection sensor technology – OFIS - combine to identify various disease states and conditions via proprietary breath biomarkers, volatile organic compounds (VOC’s). DECIPHER is disease agnostic and will speed diagnosis, while improving accuracy over currently available diagnostic methods. The tests use a noninvasive 4-minute breath sample with analysis taking ~15 minutes on our portable, battery powered platform. Initial products include fungal pneumonias, lung cancer (staging, monitoring, differential diagnosis and screening) and C. difficile.

Member
FiteBac Pharma

FiteBac Technology/FiteBac Pharma's K21 uniquely targets the underlying disease state, given that most diseases involve microbial-associated inflammation and mitochondrial dysfunction. FiteBac Technology innovations stem from the work of numerous international academic research scientists. FiteBac Pharma K21 is the blockbuster antimicrobial small molecule designed to modulate biological, immunological, and metabolic systems for treating a wide range of infectious and inflammatory diseases. This patented drug substance has demonstrated the ability to safely eliminate bacterial, fungal, and viral infections, enhance innate immunity, induce mitophagy while improving mitochondrial and cellular metabolism, accelerate wound healing, and even promote the development of zebrafish and chickens, leading to increased adult mass. Rigorous research from Dr. Bhupesh Prusty's laboratory and Dr Christopher Rongo's laboratory is focused on various aspects of mitochondrial remodeling and reprograming, as well as mitochondrial-to-nuclear signaling with K21.

Member
Humanetics Corporation

Humanetics Corporation is a clinical-stage pharmaceutical company based in Minneapolis, Minnesota, focused on developing and commercializing products to enhance human health and wellbeing. Founded in 1988, the company specializes in radiation modulators, adjunctive oncology therapies, and pulmonary protective therapies, particularly for COVID-19. Humanetics is known for its lead drug candidate, BIO 300, which is being developed as a radioprotectant for military and civilian use, as well as a treatment to improve outcomes in cancer patients receiving radiotherapy. The company is actively engaged in research programs for non-small cell lung cancer, prostate cancer, and head and neck cancers.

Member
Physical Sciences Inc.

Physical Sciences Inc. (PSI) is an employee-owned company dedicated to inventing, demonstrating, and translating technologies that address critical national needs in defense, security, healthcare, and environmental stewardship. With over 50 years of experience, PSI combines extensive research and development capabilities with a commitment to innovation and customer focus.

Member
Qidni Labs

Qidni Labs is a NATO DIANA company recognized by Fast Company as a 2025 World Changing Idea. The company has developed a portable, nearly waterless hemodialysis system that will make treatment accessible for over 10 million patients every year.

Member
STAT Therapeutics

STAT Therapeutics is focused on developing a drug- device combination for easy, rapid administration of intramuscular, life-saving medications by users in any setting, aiming to improve access and usability for acute emergency treatments such as pain, anaphylaxis, and seizures.

Member
Armata Pharmaceuticals, Inc.

Armata Pharmaceuticals, Inc. is a clinical-stage biotechnology company dedicated to developing pathogen-specific bacteriophage therapeutics to combat antibiotic-resistant and difficult-to-treat bacterial infections. With a focus on addressing the global antibiotic resistance crisis, Armata leverages its proprietary bacteriophage-based technology to develop high-impact, best-in-class phage therapeutics. The company operates from a 56,000 square foot facility in Los Angeles, California, equipped for phage product development from bench to clinic. Armata's team of microbiologists and scientists work on discovering natural phages and enhancing them through synthetic biology and engineering to create tailored drug products for clinical trials.

Member
The University of Texas at San Antonio

The University of Texas at San Antonio (UTSA) is dedicated to the advancement of knowledge through research, teaching, and community engagement. As a premier public research university, UTSA embraces multicultural traditions and serves as a catalyst for socioeconomic development, providing access to educational excellence and preparing citizen leaders for the global environment.

Member
Auburn University

Auburn University Research & Economic Development is dedicated to advancing research and economic growth through a collaborative effort among its various colleges and departments. The organization focuses on fostering innovation, supporting faculty and student research, and facilitating partnerships with industry and government to address societal challenges and enhance the quality of life. Recent initiatives include the launch of the Team Science Series to promote interdisciplinary collaboration and the development of the Gulf Coast Engineering Research Station to address coastal environmental challenges.

Member
Vocxi Health

Vocxi Health is a diagnostic start-up focused on early disease detection through its innovative MyBreathPrint® system. This noninvasive technology allows for immediate health assessments by analyzing volatile organic compounds (VOCs) in a patient's breath, aiming to revolutionize patient care and improve health outcomes.

Member
Seek Labs

Seek Labs is a biotechnology company headquartered in Salt Lake City, Utah, dedicated to advancing scientific discovery and delivering universal healthcare solutions. The company specializes in next-generation point-of-care molecular diagnostics and programmable CRISPR-based therapeutics, aiming to bridge the gap between disease outbreak and intervention. Powered by its proprietary AI discovery engine, BioSeeker™, Seek Labs is building a modular, full-stack system that enables rapid response to emerging pathogens, scalable precision treatments, and accessible diagnostics. The company is committed to global health innovation, sustainability, and community engagement, and is a proud member of Utah's BioHive life sciences ecosystem. Seek Labs' mission is to empower individuals with healthcare solutions tailored to their specific needs, revolutionizing the detection and treatment of diseases for both human and animal health.

Member
University of Arkansas

The Institute for Integrative & Innovative Research (I3R) at the University of Arkansas is dedicated to pioneering solutions to complex societal challenges through convergence research. With a mission to advance research excellence and stimulate economic development, I3R focuses on deploying innovations at scale through collaboration across various sectors, including academia, industry, and government.

Member
The University of Texas Medical Branch at Galveston

UTMB is dedicated to supporting research, education, and scholarly endeavors, with a focus on creating the future of healthcare through innovative research and community engagement.

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