Biomanufacturing for Regenerative Medicine (Biomfg)

Purpose

This solicitation, issued MTEC, represents a Request for Project Proposals (RPP) for MTEC support of the U.S. Army Medical Research and Materiel Command (USAMRMC) Clinical and Rehabilitative Medicine Research Program (CRMRP). Strategic oversight for the award(s) supported by this RPP will be provided by will be provided by Joint Program Committee 8 (JPC‐8)/CRMRP.

MTEC operates under a prototype Other Transaction Agreement (pOTA) with USAMRMC. Proposed prototype projects should not be exploratory in nature and do require a foundation of preliminary data. As defined in the OTA Guide dated November 2018, a prototype project addresses a proof of concept, model, reverse engineering to address obsolescence, pilot, novel application of commercial technologies for defense purposes, agile development activity, creation, design, development, demonstration of technical or operational utility, or combinations of the foregoing. A process, including a business process, may be the subject of a prototype project. Although assistance terms are generally not appropriate in OT agreements, ancillary work efforts that are necessary for completion of the prototype project, such as test site training or limited logistics support, may be included in prototype projects. A prototype may be physical, virtual, or conceptual in nature. A prototype project may be fully funded by DoD, jointly funded by multiple federal agencies, cost‐shared, funded in whole or part by third parties, or involve a mutual commitment of resources other than an exchange of funds.

Scope of Work

Request for White Papers and Process Stages

MTEC recognizes that considerable effort is required to prepare a competitive proposal to MTEC. The two‐stage approach for this RPP is intended to streamline the initial proposal preparation time and effort for MTEC members. Based on the Government’s evaluation of White Papers in Stage 1, select Offerors will be invited to participate in Stage 2 and will be required to submit a full proposal for more detailed evaluation.

The due date for White Papers is found on the cover page of this RPP. White Papers may not be considered under this RPP unless the White Paper was received on or before the due date specified on the cover page.

Stage 1: White Papers submitted under this RPP shall follow the MTEC White Paper Template provided in Attachment 1.

Stage 2: Offerors whose technology solutions are selected for further consideration based on White Paper evaluation will be invited to submit a proposal in Stage 2. Notification letters will contain specific Stage 2 proposal submission requirements. An example of the proposal submission requirements is (subject to change):

• Technical Proposal according to the format provided in the Proposal Preparation Guidelines (PPG) available on the MTEC members‐only website.
• Detailed Statement of Work (SOW) according to the format provided in the notification letter.
• Cost Proposal according to the format provided in the PPG.

Potential Funding Availability

The U.S. Government (USG) currently has available approximately $6M of Fiscal Year (FY) 2018 Defense Health Program (DHP) Research, Development, Test and Evaluation (RDT&E) appropriation to support proposals received in response to this RPP. The USG expects to fund two awards at $3M (direct and indirect costs) each. Funding is dependent on the quality and number of proposals received.

The funding estimated for this RPP is approximate and subject to realignment. Funding of proposals received in response to this RPP is contingent upon the availability of federal funds for this program.

Award funding will be structured incrementally and based upon completion of milestones.

The Period of Performance (POP) is not to exceed four years.

Points of Contact

For inquiries, please direct your correspondence to Biomedical Research Associate Chuck Hutti, Ph.D. at Chuck.Hutti@ati.org.