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Explore MTEC's network of innovators, investors, and research organizations—along with patents and funding opportunities—advancing medical technologies for military and civilian health.

Showing 38 Patents
Anti-CD22 chimeric antigen receptors

16-01-2018 • US-9868774-B2

ORENTAS, RIMAS J. • MACKALL, CRYSTAL L. • PASTAN, IRA H.

US Department of Health and Human Services

Mesothelin domain-specific monoclonal antibodies and use thereof

31-10-2017 • US-9803022-B2

HO, MITCHELL • PASTAN, IRA H. • PHUNG, YEN T. • ZHANG, YIFAN • GAO, WEI • HASSAN, RAFFIT

US Department of Health and Human Services

Pseudomonas exotoxin a with less immunogenic T cell and/or B cell epitopes

19-09-2017 • US-9765123-B2

PASTAN, IRA H. • MAZOR, RONIT • ONDA, MASANORI • VASSALL, AARON • BEERS, RICHARD • EBERLE, JAIME • LIU, WENHAI

US Department of Health and Human Services

Human bispecific EGFRvIII antibody and CD3 engaging molecules

13-06-2017 • US-9676858-B2

BIGNER, DARELL • KUAN, CHIEN-TSUN • SAMPSON, JOHN • CHOI, BRYAN • PASTAN, IRA H. • GEDEON, PATRICK C.

UNITED STATES GOVERNMENT HEALTH AND HUMAN SERVICES (NIH), Secretary of, Department of • Duke University • US Department of Health and Human Services

Pseudomonas exotoxin A with less immunogenic B cell epitopes

23-05-2017 • US-9657066-B2

PASTAN, IRA H. • ONDA, MASANORI • LIU, WENHAI

US Department of Health and Human Services

Human monoclonal antibodies specific for CD22

21-03-2017 • US-9598492-B2

DIMITROV, DIMITER S. • XIAO, XIAODONG • PASTAN, IRA H.

US Department of Health and Human Services

Dual specific immunotoxin for brain tumor therapy

15-11-2016 • US-9492564-B2

BIGNER, DARELL • KUAN, CHIEN-TSUN • PASTAN, IRA H. • PEAGRAM, CHARLES

UNITED STATES GOVERNMENT HEALTH AND HUMAN SERVICES (NIH), Secretary of, Department of • National Institutes of Health NIH • Duke University

Antibody for 3′-isoLM1 and 3′,6′-iso-LD1 gangliosides

13-09-2016 • US-9441048-B2

BIGNER, DARELL • KUAN, CHIEN-TSUN • PASTAN, IRA H. • PIAO, HAILAN

UNITED STATES GOVERNMENT HEALTH AND HUMAN SERVICES (NIH), Secretary of, Department of • Duke University • US Department of Health and Human Services

Mesothelin antibodies and methods for eliciting potent antitumor activity

16-08-2016 • US-9416190-B2

HO, MITCHELL • PASTAN, IRA H. • DIMITROV, DIMITER S. • TANG, ZHEWEI • FENG, MINGQIAN • GAO, WEI

US Department of Health and Human Services

Mesothelin domain-specific monoclonal antibodies and use thereof

09-08-2016 • US-9409992-B2

HO, MITCHELL • PASTAN, IRA H. • PHUNG, YEN T. • ZHANG, YIFAN • GAO, WEI • HASSAN, RAFFIT

US Department of Health and Human Services

Immunogenic POTE peptides and methods of use

19-07-2016 • US-9394352-B2

BERZOFSKY, JAY A. • HUANG, YI-HSIANG • TERABE, MASAKI • PASTAN, IRA H.

US Department of Health and Human Services

Modified Pseudomonas exotoxin A

12-07-2016 • US-9388222-B2

PASTAN, IRA H. • MAZOR, RONIT • ONDA, MASANORI • LEE, BYUNGKOOK • NIEDERFELLNER, GERHARD • IMHOF-JUNG, SABINE • BRINKMANN, ULRICH • GEORGES, GUY

Hoffmann La Roche Inc • US Department of Health and Human Services

Anti-mesothelin chimeric antigen receptors

07-06-2016 • US-9359447-B2

FELDMAN, STEVEN A. • ROSENBERG, STEVEN A. • PASTAN, IRA H.

US Department of Health and Human Services

Pseudomonas exotoxin A with less immunogenic T cell and/or B cell epitopes

24-05-2016 • US-9346859-B2

PASTAN, IRA H. • MAZOR, RONIT • ONDA, MASANORI • VASSALL, AARON • BEERS, RICHARD • EBERLE, JAIME • LIU, WENHAI

US Department of Health and Human Services

Human monoclonal antibodies specific for CD22

08-03-2016 • US-9279019-B2

DIMITROV, DIMITER S. • XIAO, XIAODONG • PASTAN, IRA H.

US Department of Health and Human Services

Pseudomonas exotoxin A with less immunogenic B cell epitopes

08-12-2015 • US-9206240-B2

PASTAN, IRA H. • ONDA, MASANORI • LIU, WENHAI

United States, Helath And Human Services, Secretary of, Department of • US Department of Health and Human Services

Immunogenic peptides and methods of use

03-11-2015 • US-9175057-B2

SCHLOM, JEFFREY • TSANG, KWONG-YOK • PASTAN, IRA H.

US Department of Health and Human Services

Pseudomonas exotoxin a with reduced immunogenicity

20-01-2015 • US-8936792-B2

PASTAN, IRA H. • BEERS, RICHARD • ONDA, MASANORI

National Institutes of Health NIH • US Department of Health and Human Services

Mutated Pseudomonas exotoxins with reduced antigenicity

09-12-2014 • US-8907060-B2

PASTAN, IRA H. • ONDA, MASANORI • NAGATA, SATOSHI • FITZGERALD, DAVID • KREITMAN, ROBERT • LEE, BYUNGKOOK

US Department of Health and Human Services

Deletions in domain II of pseudomonas exotoxin a that remove immunogenic epitopes

28-10-2014 • US-8871906-B2

PASTAN, IRA H. • WELDON, JOHN • FITZGERALD, DAVID

US Department of Health and Human Services

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