Durable antimicrobial coating composition
Inventors
HUEN, Ngar Yee • KWOK, Connie Sau Kuen • CHEUK, Wah Kit
Assignees
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Publication Number
US-9957396-B2
Publication Date
2018-05-01
Expiration Date
Abstract
The presently claimed invention provides a coating composition for an antimicrobial coating, and a method for synthesizing the coating composition. A coating method for deposition of the antibacterial coating is also provided. The antimicrobial coating of the present invention is effective in providing antimicrobial function, easy to be manufactured, stable and durable.
Core Innovation
A coating composition is prepared by providing a silver nanoparticle dispersion and chlorhexidine, dissolving chitosan in acetic acid to form a chitosan solution, incubating glutaraldehyde with the chitosan solution to form a solution of crosslinked chitosan, and mixing the silver nanoparticle dispersion and chlorhexidine with the solution of crosslinked chitosan to form the coating composition. The coating composition comprises 0.0002%-0.001% w/v of silver nanoparticles, 0.48%-1.9% w/v chitosan, 0.48-1.9% v/v acetic acid, 0.05%-0.2% v/v chlorhexidine, and 0.06%-0.35% glutaraldehyde v/v.
The disclosed approach addresses antimicrobial performance associated with a durable, stable, transparent antimicrobial coating. The coated material is described as being able to air-dry at room temperature without curing, and the antimicrobial property is described as inhibiting the growth of various microorganisms, including viruses, fungi, gram-positive and gram-negative bacteria, including MRSA and ESBL-type bacteria, and bacterial endospores.
The antimicrobial coating composition is further described as being applicable to multiple substrate types including glass, plastic, metal, painted wood, and ceramic by spraying, spreading, or wiping. The coating is described as exhibiting durability and activity over time, including reported stability of the composition and antimicrobial activity on coated surfaces, while maintaining coating appearance. The document also states compliance aspects including RoHS and SVHC.
Claims Coverage
The independent claims define one preparation method for a coating composition, with multiple dependent claim refinements that add functional performance, drying/curing conditions, antimicrobial spectrum, and substrate material types. The independent claim includes three inventive features: the specific components and mixing step, the use of chitosan dissolved in acetic acid, glutaraldehyde as the chitosan cross-linker, and specified component concentration ranges.
Preparing crosslinked chitosan with acetic acid and glutaraldehyde
Dissolving chitosan in an acidic organic solvent to form a chitosan solution; incubating a chitosan cross-linker with the chitosan solution to form a solution of crosslinked chitosan; wherein the acidic organic solvent is acetic acid and the chitosan cross-linker is glutaraldehyde.
Mixing silver nanoparticles and chlorhexidine into crosslinked chitosan
Providing a silver nanoparticle dispersion and chlorhexidine; and mixing the silver nanoparticle dispersion and chlorhexidine with the solution of crosslinked chitosan to form said coating composition.
Specified concentration ranges for antimicrobial coating composition components
Wherein said coating composition comprises 0.0002%-0.001% w/v of silver nanoparticles, 0.48%-1.9% w/v chitosan, 0.48-1.9% v/v acetic acid, 0.05%-0.2% v/v chlorhexidine and 0.06%-0.35% glutaraldehyde v/v.
Across the independent claim, the coverage centers on forming crosslinked chitosan using acetic acid and glutaraldehyde, then combining that crosslinked chitosan with a silver nanoparticle dispersion and chlorhexidine to yield an antimicrobial coating composition with specified concentration ranges. Dependent claim coverage further narrows outcomes and contexts including durable, stable antimicrobial coating performance, air-drying at room temperature without curing, and antimicrobial inhibition across enumerated microorganism categories, as well as application to specified surface materials.
Stated Advantages
Provides a durable, stable, transparent antimicrobial coating.
Supports air drying at room temperature without curing.
Exhibits antimicrobial property inhibiting growth of viruses, fungi, gram-positive and gram-negative bacteria, including MRSA and ESBL-type bacteria, and bacterial endospores.
Shows resistance to cleaning agents and repeated wiping.
Documented Applications
Application of the antimicrobial coating composition to surfaces including glass, plastic, metal, painted wood, and ceramic.
Coating deposition on the above surfaces by spraying, spreading, or wiping.
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