Closure piece for a powder syringe, and powder syringe

Inventors

Glocker, Joachim • Roedle, Tilman

Assignees

Vetter Pharma Fertigung GmbH and Co KG

Abstract

A closure piece for a powder syringe has a main body and a sealing element. The sealing element is disposed on the main body such that it rests in a sealing manner against a distal opening of a powder syringe when the closure piece is disposed in the closing position thereof on the powder syringe. A channel passes through the main body and the sealing element and has a proximal and a distal end. The closure piece includes a retaining element configured and/or disposed such that, prior to an activation of the powder syringe, any powder from a chamber of the powder syringe is at least substantially prevented from penetrating the channel when the closure piece is disposed in the closing position thereof on the powder syringe.

Core Innovation

The patent discloses a closure piece for a powder syringe in which a sealing element is disposed on a main body and rests in a sealing manner against a distal opening when the closure piece is disposed in a closing position on the powder syringe. The closure piece includes a channel passing through the main body and the sealing element, the channel having a proximal end and a distal end, and a closure cap includes a projection passing through the channel, the projection having a thickened portion defining a retaining element to at least substantially prevent powder coming from a chamber of the powder syringe from penetrating the channel during the closing position.

In the disclosed configuration, the sealing element is elastic and is compressed when the projection is inserted into the channel, with the rod-like projection having a projection diameter within a section of the channel passing through the sealing element that is greater than a channel diameter of the section. As a result, the rod-like projection radially compresses the sealing element and tightly seals the proximal end of the channel, thereby preventing powder penetration and avoiding clumping or agglomeration and channel blockage during storage, including when used with dual-chamber systems.

The patent also discloses alternative retaining-element embodiments within the closure piece, including a slotted membrane retaining element that opens or bursts under pressure to release the channel, a displaceable ball retaining element that seals the proximal end in a storage state and moves out upon activation, and a soluble or lyophilized plug retaining element that dissolves when activated to release fluid communication. Further embodiments include a closure-piece disc sealing against a distal narrowing, held by a safety-pin projection that is displaced on activation to form a flow path.

Claims Coverage

The partial content provides two independent claims. Each claim centers on a closure piece with a sealing element and a channel, and on a closure cap projection with a thickened retaining portion that substantially prevents powder from penetrating the channel during a closing position, while compressing an elastic sealing element to tightly seal the proximal end of the channel.

Both independent claims require an elastic sealing element and a channel sealed at the proximal end by a closure cap projection with a thickened retaining portion, configured so that insertion of the rod-like projection compresses the sealing element and radially seals the proximal end while substantially preventing powder from penetrating the channel during the closing position. Claim 14 further requires the sealing element to rest against a distal-most surface and circumferentially surround the opening, and requires the thickened portion thickness perpendicular to the projection axis to be thicker than an adjacent portion.

Stated Advantages

Documented Applications