Fully implantable direct cardiac and aortic compression device
Inventors
Criscione, John C. • Leschinsky, Boris
Assignees
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Publication Number
US-9833551-B2
Publication Date
2017-12-05
Expiration Date
Abstract
The present invention provides a combined direct cardiac compression and aortic counterpulsation device comprising: an inflatable direct cardiac compression jacket configured when inflated to directly compress a heart and assist in displacing blood therefrom, an aortic counterpulsation chamber configured when inflated to displace aortic volume for the purposes of causing a counterpulsation effect, and a driver operably connected to said inflatable direct cardiac compression jacket and to said aortic counterpulsation chamber, said driver is configured to inflate said direct cardiac compression jacket and to deflate said aortic counterpulsation chamber during systole of the heart; said driver is further configured to deflate said direct cardiac compression jacket and to inflate said aortic counterpulsation chamber during diastole of the heart.
Core Innovation
The invention is a combined direct cardiac compression and aortic counterpulsation device in which an inflatable direct cardiac compression jacket directly compresses a heart and assists in displacing blood therefrom. The jacket includes an inner membrane attached to an outer member and contoured to surround a heart so that it compresses the heart during contraction without inverting or significantly perturbing the curvatures of the heart. A fluid between the outer member and the inner membrane is pressurized to exert a non-curvature-inverting contraction strain pattern when used on a heart.
The device also includes an aortic counterpulsation chamber configured so that, when inflated, it displaces aortic volume for the purposes of causing a counterpulsation effect. A driver is operably connected to the inflatable direct cardiac compression jacket and the aortic counterpulsation chamber. The driver is configured to move the fluid to inflate the direct cardiac compression jacket and to deflate the aortic counterpulsation chamber during systole of the heart.
During diastole of the heart, the driver is further configured to deflate the direct cardiac compression jacket and to inflate the aortic counterpulsation chamber. In alternative independent claim form, the device uses a driver configured to shuttle a drive fluid back and forth between the direct cardiac compression jacket and the aortic counterpulsation chamber to alternate inflations and deflations thereof. Another form includes a first inflatable component in direct contact with a heart and a second inflatable component in direct contact with at least one great artery, with the driver transferring fluid between the components during systolic ejection and diastolic filling.
Claims Coverage
The partial content includes four independent claims, which share a coordinated driver-driven alternation of inflatable cardiac compression and inflatable aortic counterpulsation across systole and diastole, including options for membrane/jacket contouring and fluid shuttling between components. Across the independent claims, the inventive features focus on combined direct compression and counterpulsation using inflatable components and a coordinated driver that changes inflation states based on cardiac phase.
Inflatable, contoured direct cardiac compression jacket with non-curvature-inverting contraction strain pattern
An inflatable direct cardiac compression jacket configured when inflated to directly compress a heart and assist in displacing blood therefrom, wherein the inflatable direct cardiac compression jacket comprises an inner membrane attached to an outer member and contoured to surround a heart to compresses the heart during contraction without inverting or significantly perturbing the curvatures of the heart and a fluid between the outer member and the inner membrane, wherein the device exerts a non-curvature-inverting contraction strain pattern when used on a heart, when the fluid is pressurized.
Inflatable aortic counterpulsation chamber to displace aortic volume for counterpulsation effect
An aortic counterpulsation chamber configured when inflated to displace aortic volume for the purposes of causing a counterpulsation effect.
Driver inflating cardiac compression during systole and inflating aortic counterpulsation during diastole
A driver operably connected to said inflatable direct cardiac compression jacket and to said aortic counterpulsation chamber, said driver is configured to move the fluid to inflate said direct cardiac compression jacket and to deflate said aortic counterpulsation chamber during systole of the heart; said driver is further configured to deflate said direct cardiac compression jacket and to inflate said aortic counterpulsation chamber during diastole of the heart.
Shuttling drive fluid between cardiac compression jacket and aortic counterpulsation chamber
A driver operably connected to said inflatable direct cardiac compression jacket and to said aortic counterpulsation chamber, said driver is configured to shuttle a drive fluid back and forth between said direct cardiac compression jacket and said aortic counterpulsation chamber to alternate inflations and deflations thereof.
Direct pulsation in a first inflatable component and counterpulsation in a second inflatable component
A first inflatable component in direct contact with a heart, a second inflatable component in direct contact with at least one great artery, and a driver operably connected to said first and second inflatable components, wherein said device is configured to fill said first inflatable component with fluid at least partially removed from said second inflatable component during systolic ejection by the heart; said device is further configured to fill said second inflatable component with fluid at least partially removed from said first inflatable component during diastolic filling of the heart.
Resilient inner panel and inflatable outer panel to affect end-diastolic and end-systolic heart volumes without inverting heart curvatures
An inflatable direct cardiac compression device comprising a resilient inner panel in contact with a heart periphery comprising one or membranes contoured to provide curvatures generally in the shape of the heart to supply resistance to the movement of the heart to affect the end-diastolic heart volume, an inflatable outer panel comprising one or more inflatable membranes positioned at least partially around the resilient inner panel to inflate and provide resistance to the movement of the heart to affect the end-systolic heart volume without inverting or significantly perturbing the curvatures of the heart, and one or more fluid connections in communication with the inflatable outer panel for inflation and deflation.
Aortic counterpulsation device with shell, flexible membrane, and inlet/outlet port removably positioned against a radially outer side of aortic curvature
An aortic counterpulsation device comprising a shell comprising an outer surface and a substantially concave inner surface, a flexible membrane coupled to the shell to form an inflatable space therebetween, wherein the flexible membrane has a deflated configuration and an inflated configuration, an inlet/outlet port in fluid communication with the inflatable space, and coupled to the shell to removeably position to hold the flexible membrane against a radially outer side of a curvature of the aorta.
Driver alternately inflating cardiac compression and deflating/inflating aortic counterpulsation across systole and diastole
A driver operably connected to the one or more fluid connections of the inflatable direct cardiac compression device and to the aortic counterpulsation device to inflate the inflatable direct cardiac compression device and to deflate the aortic counterpulsation device during systole of the heart and to deflate the inflatable direct cardiac compression device and to inflate the aortic counterpulsation device during diastole of the heart.
Across the independent claims, the document covers combined direct cardiac compression and aortic counterpulsation using inflatable components and a driver configured to coordinate phase-dependent alternation of inflation states. The claim set emphasizes a contoured, non-curvature-inverting cardiac compression jacket with pressurized fluid producing a non-curvature-inverting contraction strain pattern, an inflatable aortic counterpulsation chamber or aortic counterpulsation device with a shell and flexible membrane forming an inflatable space, and driver-based fluid movement or shuttling that alternates inflations and deflations between cardiac and aortic inflatable components during systole and diastole.
Stated Advantages
Reduction of infection.
Reduction of thrombosis.
Reduction of coagulation.
No blood contact interface.
Adaptive grading/weaning support.
Compatibility with combination therapies.
Documented Applications
Use of a fully implantable combined device for direct cardiac compression and aortic counterpulsation coordinated across systole and diastole.
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