Implantable luminal devices
Inventors
Rudakov, Leon • Black, Andrew • Leopold, Andrew R. • Jensen, Kelly
Assignees
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Publication Number
US-9737306-B2
Publication Date
2017-08-22
Expiration Date
Abstract
An implant may include a frame and a cover to facilitate endoluminal vessel occlusion, selective release of embolic material toward a target region, and/or endoluminal stenting. The frame of the implant provides radial expansion properties to secure the cover within a body vessel. The cover and/or the frame can occlude flow of a fluid through the body vessel.
Core Innovation
The invention provides an expandable device for delivery to a target location in a body vessel. The device includes a body comprising first and second elongate members coupled together at proximal, medial, and distal locations, where the body has a proximal end and is freely movable relative to a distal end. The elongate members extend along arcuate paths in opposite circumferential directions from proximal to medial and from medial to distal, interconnecting at the medial location, and the spaced arcuate portions collectively define a frame having a central lumen extending therethrough.
The first elongate member defines a first support element with a first maximum expanded diameter, and the second elongate member defines a second support element with a second maximum expanded diameter different from the first maximum expanded diameter. In one structural variant, the first and second elongate members collectively form first and second hoop elements that are longitudinally spaced apart to collectively define a frame having a central lumen, with the hoop elements having different maximum expanded diameters.
Expandable occlusive implant structures are described that include at least one heat-set or self-expanding filament or wire configured to expand and generate radially expansive forces. The implant includes an occlusive cover that occludes vessel flow, where the expanded cross-sectional dimension exceeds a vessel diameter, and the expandable filament or wire is pre-biased to expand into a selected 3D shape. An implant architecture is also described using a support frame and an occlusive cover, including a proximal anchor, a connection bridge, and a distal anchor, with collapsed configurations and tapered arrangements.
The document also recites coupling and release-related structures, including proximal and distal engagement sections with releasable actuation using pull members, clasps and perforations, an optional port and lumen, and retaining mechanisms to maintain an expanded state, such as an inner protrusion with a ratchet/pawl. It further includes delivery by holding the filament in a compressed state within a catheter and releasing it to expand within the cover, shape-setting and catheter ejection, an optionally detachable pusher, and flow-regulating and occlusion implant variants including covered stent structures, adjustable components, and TIPS and DSRS-related flow control.
Claims Coverage
The provided claim set includes two independent claims covering an expandable delivery device having a frame with a central lumen defined by first and second elongate members, with different maximum expanded diameters and arcuate circumferential path arrangements, including hoop-element embodiments. A second set of claims is not explicitly described in patent.
First and second elongate members forming a frame with central lumen
The device comprises a body with first and second elongate members coupled at proximal, medial, and distal locations, extending along arcuate paths in opposite circumferential directions to interconnect at the medial location, with spaced portions collectively defining a frame having a central lumen extending therethrough.
Different maximum expanded diameters defining first and second support elements
The first and second elongate members collectively define a first support element having a first maximum expanded diameter and a second support element having a second maximum expanded diameter different from the first maximum expanded diameter.
First and second hoop elements longitudinally spaced apart with central lumen
First and second elongate members are coupled together at proximal, medial, and distal locations to form first and second hoop elements, the first and second hoop elements being longitudinally spaced apart to collectively define a frame having a central lumen extending therethrough, and the first and second hoop elements having different maximum expanded diameters.
Arcuate opposite circumferential extensions to form hoop elements
The first and second elongate members extend arcuately from the proximal location to the medial location in opposite circumferential directions to form the first hoop element, and extend arcuately from the medial location to the distal location in opposite circumferential directions to form the second hoop element.
Overall, the independent claims focus on an expandable vessel-delivery frame defined by first and second elongate members or hoop elements whose arcuate circumferential extensions create a central lumen and whose support or hoop elements expand to different maximum expanded diameters.
Stated Advantages
Provides occlusion of vessel flow using an occlusive cover and expandable filaments generating radially expansive forces.
Supports expandable implant geometries through heat-set or self-expanding filaments or wires pre-biased to expand into a selected 3D shape.
Enables maintaining an expanded state using retaining mechanisms such as a ratchet/pawl.
Includes torque-resistant delivery catheter distal tip structures using keyed coils and helical kerfs or filaments.
Documented Applications
TIPS-related flow control or occlusion applications.
DSRS-related flow control or occlusion applications.
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