Biodegradable endoprostheses and methods of their fabrication
Inventors
Assignees
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Publication Number
US-9730819-B2
Publication Date
2017-08-15
Expiration Date
Abstract
A biodegradable stent prosthesis formed from a degradable material, having a plurality of luminal, abluminal, and side surface regions, wherein a surface portion extending between the abluminal and luminal surface region of at least some structural elements is convex.
Core Innovation
The disclosed invention is a biodegradable expandable stent prosthesis formed from a polymeric tubular body patterned into a stent. Its structural elements comprise struts joined by crowns and feature abluminal, luminal, and two side surface regions. Treatment modifies at least some structural elements such that their thickness increases and their width decreases relative to initial dimensions, while the stent remains expandable and retains sufficient strength to support a body lumen.
The structural elements exhibit geometries including concave luminal and abluminal surfaces, convex or bulbous side regions, and dogbone cross-sections resulting from material redistribution. These structural configurations provide vessel-wall engagement or apposition, drug coating or delivery, and resistance to strut rotation or fracture during deployment. Furthermore, the resulting geometry enhances radial strength, flexibility, trackability, and balloon retention within a body lumen.
Claims Coverage
The provided relevant claims identify one independent claim, claim 1, covering four principal inventive features of a biodegradable polymeric stent.
Biodegradable polymeric stent
A biodegradable stent prosthesis comprises a polymeric material and is formed from a tubular body patterned into a stent.
Patterned structural elements
The stent comprises structural elements with abluminal, luminal, and two side surface regions, wherein the structural elements comprise struts joined by crowns having an initial thickness and an initial width.
Treatment increasing thickness and reducing width
At least some structural elements are treated such that their thickness after treatment is larger than their initial thickness and their width after treatment is smaller than their initial width.
Expandable stent with lumen-supporting strength
The stent prosthesis is expandable from a crimped configuration to an expanded larger configuration and maintains sufficient strength to support a body lumen.
The independent claim combines a patterned biodegradable polymeric stent, treated structural elements exhibiting increased thickness and decreased width, and expandability from a crimped state to an expanded configuration with sufficient strength to support a body lumen.
Stated Advantages
The disclosed structural shapes are stated to improve radial strength, flexibility, trackability, and balloon retention.
The disclosed structural shapes are stated to improve vessel-wall engagement or apposition and drug coating or delivery.
The structural geometries are stated to provide increased resistance to strut rotation or fracture during deployment and support within the vessel.
Documented Applications
A biodegradable stent prosthesis expandable from a crimped configuration to an expanded configuration for supporting a body lumen.
Drug coating or delivery utilizing the biodegradable stent prosthesis.
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