Implants and methods for correcting tissue defects

Inventors

Engqvist, Håkan • Engstrand, Thomas • Åberg, Jonas • Bohlin, Jan

Assignees

Ossdsign AB

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Publication Number

US-9445900-B2

Patent

Publication Date

2016-09-20

Expiration Date


Abstract

An implant comprises a plurality of discrete biocompatible molded cement mosaic plates of maximum width w and thickness d connected by wire arms molded into and extending substantially laterally from the mosaic plates. Neighboring mosaic plates are separated by a gap of width t, and at least some of the mosaic plates have a hexagon shape.

Core Innovation

The invention relates to mosaic implants for correcting tissue defects. The implant includes a plurality of discrete biocompatible molded cement mosaic plates, each having a maximum width w and a thickness d. Neighbouring mosaic plates are separated by a gap of width t, and at least some of the mosaic plates have a hexagon shape.

The mosaic plates are connected by wire arms that are molded into and extend substantially laterally from the mosaic plates. The described structural principles include discrete biocompatible cement plates whose dimensions w and d are separated by gaps t and connected via wire-retaining channels that allow the wire anchoring system to be integrated into the cement mosaic.

The mosaic plates are moulded cement mosaic plates that can include hexagon-shaped plates, and optional cement skin features between plates. The document describes cement skin as a frangible cement skin between plates, and moulding and manufacturing concepts including mould cavities and use of non-aqueous hydraulic calcium-phosphate cement precursors that harden to form the cement mosaic plates.

Claims Coverage

The independent claim covers a mosaic implant formed from discrete biocompatible molded cement mosaic plates having defined maximum width w and thickness d, arranged as hexagons and connected by laterally extending wire arms, with neighbouring plates separated by a gap width t. The provided set of dependent claim refinements specifies main inventive features including specific cement material, dimensional constraints, and hexagonal geometry relationships for slanted side walls.

Discrete molded cement mosaic plates with gap separation and hexagon shape

An implant comprising a plurality of discrete biocompatible molded cement mosaic plates of maximum width w and thickness d connected by wire arms molded into and extending substantially laterally from the mosaic plates, wherein neighbouring mosaic plates are separated by a gap of width t, and wherein at least some of the mosaic plates have a hexagon shape.

Laterally extending wire arms molded into the cement mosaic plates

Wire arms molded into and extending substantially laterally from the mosaic plates, connecting the discrete molded cement mosaic plates.

Hexagon-shaped plates formed from Monetite

At least some of the mosaic plates having a hexagon shape and the molded cement mosaic plates comprising monetite.

Acidic cement composition forming Monetite-containing plates

Mosaic plates made of Monetite formed from an acidic cement composition comprising beta-tricalcium phosphate and monocalcium phosphate monohydrate.

Dimensional constraints for maximum width w and inter-plate gap t

Each mosaic plate has a maximum width w within a defined range, and the inter-plate gap t is less than a specified threshold.

Slanted hexagonal side wall geometry with top wider than bottom

Hexagonal mosaic plates with slanted side walls such that the maximum width of the top hexagonal surface is greater than the maximum width of the bottom hexagonal-shaped surface in each plate with slanted side walls.

Overall, the claim set centers on a mosaic implant made of discrete molded cement hexagon plates separated by a defined gap and connected by laterally extending wire arms, with refinements focusing on Monetite-containing plates, acidic cement composition, dimensional constraints for w and t, and slanted-hexagon geometric relationships.

Stated Advantages

Not explicitly described in patent.

Documented Applications

Restoring cranial bone defects using a Ti-wire implant with acidic calcium phosphate cement for two patients with CT follow-up showing good positioning and lack of infection, inflammation, skin penetration, and early resorption at 3 months.

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