Detection of dynamic hyperinflation in spontaneously breathing mechanically ventilated patients
Inventors
Sinderby, Christer • Beck, Jennifer • Comtois, Norman • Grasselli, Giacomo
Assignees
Interested in licensing this patent?
MTEC can help explore whether this patent might be available for licensing for your application.
Publication Number
US-9308338-B2
Publication Date
2016-04-12
Expiration Date
Abstract
A method and device for determining dynamic hyperinflation during mechanical ventilation of a spontaneously breathing patient, wherein mechanical ventilation is removed during one breath of the patient, inspiratory and expiratory volumes of the patient are measured during the one breath, and a difference between the inspiratory and expiratory volumes measured during the one breath is calculated. Dynamic hyperinflation of the patient's lungs is indicated in relation to the calculated difference.
Core Innovation
The invention determines dynamic hyperinflation during mechanical ventilation of a spontaneously breathing patient by temporarily removing mechanical ventilation during one breath. During the monitored breath, inspiratory and expiratory volumes of the patient are measured while mechanical ventilation is removed, and a calculator derives a value by calculating a difference between the inspiratory and expiratory volumes.
Presence or absence of dynamic hyperinflation is indicated by an indicator based on the position of the calculated value with respect to a first value indicative of presence of dynamic hyperinflation and a second value indicative of absence of dynamic hyperinflation. The calculated difference can be implemented as an explicit ratio including Vins/Vexp, with the decision based on whether the ratio value is positioned relative to reference expectations for presence versus absence.
A device architecture is provided including a controller for removing mechanical ventilation during the one breath, a sensor for inspiratory and expiratory volumes during said one breath, a calculator for the difference value, and an indicator for the presence or absence decision. Physiological rationale is described in relation to air-trapping and intrinsic PEEPi, linking behavior of Vins and Vexp during ventilation removal to the indication of dynamic hyperinflation.
Claims Coverage
The document includes two independent claims, one method claim and one device claim, each having a core set of inventive features centered on removing mechanical ventilation during one breath, measuring inspiratory and expiratory volumes, calculating a difference value, and indicating presence or absence relative to reference values.
Temporary removal of mechanical ventilation during one breath
A method comprising removing, using a controller, mechanical ventilation during one breath of the patient; and a device comprising a controller for removing mechanical ventilation during one breath of the patient.
Measuring inspiratory and expiratory volumes during the monitored breath
A method comprising measuring inspiratory and expiratory volumes of the patient during said one breath; and a device comprising a sensor of inspiratory and expiratory volumes of the patient during said one breath.
Calculating a difference value between inspiratory and expiratory volumes
A method comprising calculating, using a calculator, a difference between the inspiratory and expiratory volumes measured during said one breath, the calculated difference having a value; and a device comprising a calculator of a difference between the inspiratory and expiratory volumes sensed during said one breath, the calculated difference having a value.
Indicating presence or absence of dynamic hyperinflation based on position relative to first and second values
A method comprising indicating, using an indicator, presence or absence of dynamic hyperinflation of the patient's lungs on the basis of a position of the value of the calculated difference with respect to a first value indicative of presence of dynamic hyperinflation and a second value indicative of absence of dynamic hyperinflation; and a device comprising an indicator of presence or absence of dynamic hyperinflation of the patient's lungs on the basis of a position of the value of the calculated difference with respect to a first value indicative of presence of dynamic hyperinflation and a second value indicative of absence of dynamic hyperinflation.
Across the method and device, the independent claims consistently cover a controller-removal of mechanical ventilation during one breath, sensing or measuring inspiratory and expiratory volumes during that breath, calculating a difference including Vins/Vexp, and indicating dynamic hyperinflation presence or absence based on the calculated value’s position relative to reference values for presence and absence.
Stated Advantages
Not explicitly described in patent.
Documented Applications
Not explicitly described in patent.
Interested in licensing this patent?