Medical implant
Inventors
Busold, Rany • You, Changcheng • Concagh, Daniel • Core, Lee • Ho, Kicherl • Palasis, Maria • Sharma, Upma • Zugates, Greg
Assignees
Interested in licensing this patent?
MTEC can help explore whether this patent might be available for licensing for your application.
Publication Number
US-9278016-B2
Publication Date
2016-03-08
Expiration Date
Abstract
Disclosed is a self-expanding medical implant for placement within a lumen of a patient. The implant comprises a woven or non-woven structure having a substantially tubular configuration, and is designed to be low-profile such that it is deliverable with a small diameter catheter. The implant has a high recoverability and desired mechanical properties.
Core Innovation
The invention describes an implantable medical device with a self-expanding biodegradable tubular structure. The structure comprises at least one biodegradable strand and a second biodegradable material that at least partially conformally coats the strand. In some embodiments, the coating is a thermoset copolymer. The structure recovers toward its manufactured diameter after crimping.
The coating improves crimp recovery and radial mechanics, wherein coated examples recover up to about 95% of their original diameter compared with about 50% for uncoated examples. The disclosure describes braided strands and unitary frameworks for the tubular structure. The implant is intended for placement in bodily lumens or cavities, though the specific problem solved is not explicitly described in patent.
Claims Coverage
The four independent claims cover self-expanding implantable tubular structures comprising biodegradable strands and conformal biodegradable coatings, defining four inventive features with specified manufactured diameters and crimp recovery thresholds.
Biodegradable conformal coating with recovery after crimping below 50% of the manufactured diameter
An implantable medical device comprising a self-expanding tubular structure with at least one strand comprising a first biodegradable material and a second biodegradable material at least partially conformally coating the strand. The manufactured first diameter is greater than 2.5 mm, and the structure recovers to at least 90% of that diameter after being crimped to less than 50% of it.
Thermoset copolymer coating with decreasing blood vessel wall force
An implantable medical device comprising a self-expanding tubular structure with at least one strand comprising a first biodegradable polymer and a second biodegradable polymer conformally coating the strand, the second polymer being a thermoset copolymer. The manufactured first diameter is greater than 4.5 mm; the structure recovers to at least 90% of that diameter after crimping below 50%, and exerts a force against a blood vessel wall immediately after implantation that decreases over time.
Biodegradable conformal coating with recovery after crimping below 70% of the manufactured diameter
An implantable medical device comprising a self-expanding tubular structure with at least one strand comprising a first biodegradable material and a second biodegradable material at least partially conformally coating the strand. The manufactured first diameter is greater than 2.5 mm, and the structure recovers to at least 90% of that diameter after being crimped to less than 70% of it.
Thermoset copolymer coating with decreasing blood vessel wall force after crimping below 70% of the manufactured diameter
An implantable medical device comprising a self-expanding tubular structure with at least one strand comprising a first biodegradable polymer and a second biodegradable polymer conformally coating the strand, the second polymer being a thermoset copolymer. The manufactured first diameter is greater than 4.5 mm; the structure recovers to at least 90% of that diameter after crimping below 70%, and exerts a force against a blood vessel wall immediately after implantation that decreases over time.
The independent claims encompass two related configurations of biodegradable, self-expanding tubular structures: one configuration defines a conformal biodegradable coating with specified diameter recovery thresholds, while another configuration defines a thermoset copolymer coating providing a force against a blood vessel wall that decreases over time.
Stated Advantages
The coating improves crimp recovery and radial mechanics. Coated examples recover up to about 95% of their original diameter, compared with about 50% for uncoated examples.
Documented Applications
The implant is intended for placement in bodily lumens or cavities, including implantation in a blood vessel.
Interested in licensing this patent?