Herbal supplements and methods of use thereof

Inventors

Brown, Kenneth • SCOTT, Brandi M.

Assignees

KBS Research LLC

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Publication Number

US-9248158-B2

Patent

Publication Date

2016-02-02

Expiration Date


Abstract

In one embodiment, the present application provides an herbal supplement and method for treating bloating, constipation and/or weight gain in a human subject comprising orally administering to a subject in need thereof an effective amount of the herbal supplement comprising a red quebracho extract. In other embodiments, the supplement may additionally include a triterpenoid saponin, an anti-spasmodic agent, or both.

Core Innovation

The invention relates to an herbal supplement comprising a red quebracho extract, an herbal composition comprising a triterpenoid saponin, and an anti-spasmodic agent. The red quebracho extract is provided in an amount between about 0.5% to about 75% by weight of the total supplement, the herbal composition is provided between about 10% to about 90% by weight, and the anti-spasmodic agent is provided between about 2% to about 70% by weight.

The red quebracho extract is described in connection with condensed tannins, including red quebracho species such as Shinopsis (red quebracho). The herbal composition comprising a triterpenoid saponin is associated with herbal sources including Aesculus hippocastanum extract and/or Sapindus/Satindus species extracts, such as Satindus trifoliatus extract. The anti-spasmodic agent is specifically described as peppermint oil in at least one formulation.

A further aspect describes the herbal supplement as comprising a nutraceutically acceptable carrier and being provided in tablet or capsule form. The dosage form is described with dosage amounts for the red quebracho extract, the herbal composition comprising a triterpenoid saponin, and the anti-spasmodic agent, for treating bloating, constipation and/or weight gain in a human subject.

Claims Coverage

The independent claims are directed to an herbal supplement composition and a tablet or capsule dosage form that include a red quebracho extract, a triterpenoid-saponin-containing herbal composition, and an anti-spasmodic agent. Across the independent claims, the coverage includes three main inventive elements: ingredient combination, quantitative ingredient ranges, and a human-treatment formulation for bloating, constipation, and/or weight gain.

Herbal supplement with red quebracho, triterpenoid saponin, and anti-spasmodic agent for human treatment

An herbal supplement comprising a red quebracho extract; an herbal composition comprising a triterpenoid saponin; and an anti-spasmodic agent, wherein the supplement is formulated to reduce bloating, constipation and/or weight gain in a human subject.

Weight-percentage constraints for the combined herbal components

The red quebracho extract is present in an amount between about 0.5% to about 75% by weight of the total supplement, the herbal composition is present in an amount between about 10% to about 90% by weight of the total supplement, and the anti-spasmodic agent is present in an amount between about 2% to about 70% by weight of the total supplement.

Tablet or capsule dosage form with nutraceutically acceptable carrier and dosage amounts

An herbal supplement for treating bloating, constipation and/or weight gain in a human subject, comprising a red quebracho extract; a nutraceutically acceptable carrier; one or more herbal compositions comprising a triterpenoid saponin; and an anti-spasmodic agent, wherein the herbal supplement is in the form of one or more tablets or capsules, and wherein the herbal supplement is in a dosage form that comprises 10 to 1000 mg red quebracho extract, 50-2000 mg herbal composition comprising a triterpenoid saponin, and 10-1000 mg anti-spasmodic agent.

The claim coverage centers on an herbal supplement formulation that combines a red quebracho extract with a triterpenoid saponin-containing herbal composition and an anti-spasmodic agent, including specified quantitative constraints. Both independent claims tie the formulation to reducing bloating, constipation and/or weight gain in a human subject, with one independent claim requiring tablet or capsule dosage form.

Stated Advantages

Reduce bloating in a human subject.

Reduce constipation in a human subject.

Reduce weight gain in a human subject.

Provide a safety profile as assessed in a single-blinded placebo-controlled study.

Documented Applications

Treating bloating, constipation and/or weight gain in a human subject using the herbal supplement composition.

Relief of bloating/gas and constipation outcomes in a brief single-blinded placebo-controlled clinical study.

Assessment of weight change and safety in the same clinical study.

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