Composition for reduced scar formation of wounds
Inventors
Assignees
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Publication Number
US-9125892-B2
Publication Date
2015-09-08
Expiration Date
Abstract
A composition for reduced scar formation of wounds includes hydrolyzed collagen and one or more supplemental ingredients, including, lipoic acid, a zinc component, and a glucosamine component. The composition may facilitate inhibition of scar formation during wound healing. The composition may be used, for example, as a topical dressing for a wound, including, an acute or chronic wound.
Core Innovation
The document describes a wound-treatment composition intended to inhibit scar formation. The composition includes hydrolyzed collagen and supplemental components, and is associated with administration to a site of tissue injury to address wound healing with reduced scar formation.
In particular, the composition combines hydrolyzed collagen having a defined molecular weight range with zinc gluconate and sodium hyaluronate. The disclosed composition amounts are defined by specific by-weight ranges for hydrolyzed collagen, zinc gluconate, and sodium hyaluronate, with the hydrolyzed collagen molecular weight constrained to between about 10,000 Daltons and about 150,000 Daltons.
The document further discloses that additional therapeutic agents may be included, including glycosaminoglycans such as hyaluronic acid, and that the composition may be provided in topical delivery forms including gel, solution, spray, powder, film, and patch/dressing, including controlled release.
Claims Coverage
The document provides two independent claim sets. Across both, there are two main inventive aspects: (i) a defined wound-scar inhibition composition based on hydrolyzed collagen combined with zinc gluconate and sodium hyaluronate, and (ii) a molecular-weight limitation for the hydrolyzed collagen in combination with specific by-weight formulation ranges.
Administering a defined hydrolyzed collagen, zinc gluconate, and sodium hyaluronate composition to inhibit scar formation
A method for inhibiting scar formation of wounds comprising administering to a site of tissue injury a composition including about 60% by weight to about 65% by weight hydrolyzed collagen, about 25% by weight to about 35% by weight of zinc gluconate, and about 1% by weight to about 5% by weight sodium hyaluronate, wherein the hydrolyzed collagen has a molecular weight between 10,000 Daltons to about 150,000 Daltons.
Providing a defined hydrolyzed collagen, zinc gluconate, and sodium hyaluronate composition for reduced scar formation
A composition for reduced scar formation of wounds comprising about 60% by weight to about 65% by weight hydrolyzed collagen, about 25% by weight to about 35% by weight of zinc gluconate, and from about 1% by weight to about 5% by weight sodium hyaluronate, wherein the hydrolyzed collagen has a molecular weight between 10,000 Daltons to about 150,000 Daltons.
The claim coverage is directed to wound scar modulation using a composition defined by specific by-weight ranges of hydrolyzed collagen, zinc gluconate, and sodium hyaluronate, together with a defined molecular-weight range for the hydrolyzed collagen.
Stated Advantages
Inhibiting scar formation of wounds.
Reducing scar formation of wounds.
Documented Applications
Topical wound-treatment, including administration to a site of tissue injury for reduced/inhibited scar formation.
Topical delivery forms including gel, solution, spray, powder, film, patch/dressing, and controlled release.
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