Biphasic and dynamic adjustable support devices and methods with assist and recoil capabilities for treatment of cardiac pathologies

Inventors

Altman, William C. • Biswas, Saurabh • Criscione, John C. • Harrison, Lewis D. • Moreno, Michael R. • Robbins, Dennis I.

Assignees

Texas A&M University System • CORINNOVA Inc

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Publication Number

US-8944986-B2

Patent

Publication Date

2015-02-03

Expiration Date


Abstract

The present invention provides a biphasic and dynamic direct cardiac contact device adapted to be implanted in a patient suffering from congestive heart failure and related cardiac pathologies, said cardiac device having means for providing ventricular assist, ventricular support and diastolic recoil, or for providing ventricular support and diastolic recoil only.

Core Innovation

The invention relates to a biphasic direct cardiac contact device adapted to be implanted in a patient suffering from congestive heart failure and related cardiac pathologies. The device includes an adjustable passive support component in contact with an epicardial surface of the heart that continually applies support to the heart.

The adjustable passive support component constrains ventricle filling when the cardiac volume exceeds the target end diastolic volume. The device also includes an elastic memory component in contact with the adjustable passive support component, where the elastic memory component creates a negative pressure that promotes ventricle filling when a cardiac volume is lower than a target end diastolic volume.

Together, these components define a biphasic behavior that uses a phase transition point defined relative to the target end diastolic volume. The biphasic direct cardiac contact device can separately modulate the end systolic and end diastolic configurations of the heart.

Claims Coverage

Independent claim clm-00001 defines the core biphasic direct cardiac contact device with three inventive features: adjustable passive support constraining filling above target end diastolic volume, elastic memory creating negative pressure promoting filling below target end diastolic volume, and separate modulation of end systolic and end diastolic configurations. No other independent claims are provided in the supplied partial content.

Biphasic direct cardiac contact around target end diastolic volume

A biphasic direct cardiac contact device adapted to be implanted in a patient suffering from congestive heart failure and related cardiac pathologies, comprising an adjustable passive support component in contact with an epicardial surface to continually apply support, wherein the adjustable passive support component constrains ventricle filling when the cardiac volume exceeds the target end diastolic volume.

Elastic memory negative pressure promoting filling below target end diastolic volume

An elastic memory component in contact with the adjustable passive support component wherein the elastic memory component creates a negative pressure that promotes ventricle filling when a cardiac volume is lower than a target end diastolic volume.

Separate modulation of end systolic and end diastolic configurations

Wherein the biphasic direct cardiac contact device can separately modulate the end systolic and end diastolic configurations of the heart.

The provided independent claim coverage centers on a biphasic epicardial-contact device that constrains filling above a target end diastolic volume and promotes filling below it via negative pressure, while enabling separate modulation of end systolic and end diastolic configurations. Only claim clm-00001 is explicitly available in the partial content.

Stated Advantages

Continually applies support to the heart.

Constrains ventricle filling when cardiac volume exceeds the target end diastolic volume.

Creates negative pressure to promote ventricle filling when cardiac volume is lower than the target end diastolic volume.

Separately modulates end systolic and end diastolic configurations of the heart.

Documented Applications

Implantation in a patient suffering from congestive heart failure and related cardiac pathologies.

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