System for controlling means for injection of anesthetics or sedatives
Inventors
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Assignees
MemberMedsteerMedsteerMedsteer is a France-based medical technology company developing software and systems for anesthesia regulation. Its work focuses on closed-loop adjustment of intravenous anesthetic infusions using real-time patient brain-monitor data, with anesthesiologist supervision. The company also develops simulation tools and supports technical integration, clinical evaluation, collaboration, and licensing.
Medsteer is a France-based medical technology company developing software and systems for anesthesia regulation. Its work focuses on closed-loop adjustment of intravenous anesthetic infusions using real-time patient brain-monitor data, with anesthesiologist supervision. The company also develops simulation tools and supports technical integration, clinical evaluation, collaboration, and licensing.
Publication Number
US-8864702-B2
Publication Date
2014-10-21
Expiration Date
Abstract
A system comprising means for obtaining a signal representative of the electrocortical activity of the patient, means for analyzing this signal in order to derive from it a signal of depth of anaesthesia, means for monitoring the value and development over time of this signal of depth of anaesthesia, these means being associated with means for calculation of control commands of the injection means, in order to regulate automatically in closed loop the signal of depth of anaesthesia in a predetermined range around a target value, and in that the means for injection of anaesthetics comprise first means for injection of a hypnotic that receive control commands at a first frequency, and second means for injection of a morphinomimetic that receive control commands at a second frequency higher than the first frequency.
Core Innovation
The invention relates to a system for controlling injectors configured to inject anesthetics or sedatives into a patient via an intravenous anesthesia or sedation mode that is concentration or mass flow target-controlled. The system includes an electro-cortical activity input configured to transfer a signal representing electro-cortical activity of the patient, and an analysis module analyzes the signal to determine a signal of depth of anesthesia.
A monitor monitors the value and development over time of this signal, and a calculator calculates control commands of the injectors to perform automatic closed-loop regulating of the signal of depth of anesthesia within a predetermined range around a target value. The closed-loop regulating is based on monitoring and analyzing the depth-of-anesthesia signal and operates for inducing and maintaining this anesthesia or sedation.
The injector configuration includes a first injector configured to inject a hypnotic agent and a second injector configured to inject a morphinomimetic agent. The first injector receives control commands at a first frequency, while the second injector receives control commands at a second frequency higher than the first frequency.
Claims Coverage
Two independent claims are present. Across these independent claims, there are 3 main inventive features: electro-cortical activity to derive and monitor a depth-of-anesthesia signal; closed-loop regulating within a predetermined range around a target value in an intravenous concentration or mass flow target-controlled mode; and two injectors for hypnotic and morphinomimetic agents with different control-command frequencies.
Electro-cortical activity-based depth-of-anesthesia determination
An electro-cortical activity input transfers a signal representing electro-cortical activity of the patient, and an analysis module analyzes the signal to determine therefrom a signal of depth of anesthesia.
Closed-loop regulating within a predetermined range around a target value
A monitor monitors the value and development over time of the signal of depth of anesthesia, and a calculator calculates control commands of the injectors for automatic closed-loop regulating of the signal of depth of anesthesia within a predetermined range around a target value.
Two injectors with different control-command frequencies for hypnotic and morphinomimetic agents
A first injector injects a hypnotic agent and receives control commands at a first frequency, and a second injector injects a morphinomimetic agent and receives control commands at a second frequency higher than the first frequency.
The independent claims define a closed-loop IV anesthesia/sedation control system using an electro-cortical activity signal to determine and monitor a depth-of-anesthesia signal, regulate it within a predetermined range around a target value via calculated control commands, and drive separate hypnotic and morphinomimetic injectors at different control-command frequencies.
Stated Advantages
Documented Applications
No documented applications found
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