Apparatus and method for analysis of high frequency QRS complexes
Inventors
Beker, Amir • Bregman-Amitai, Orna • Zeltser, Alexander
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Publication Number
US-8706201-B2
Publication Date
2014-04-22
Expiration Date
Abstract
An apparatus for QRS waveform quantifying, comprising: an input unit, for receiving one or more high frequency (HF) range QRS complexes from one or more ECG leads, a primary analyzer, for calculating a primary index from the high frequency (HF) range QRS complex, and a secondary analyzer, connected after the primary analyzer, for deriving a secondary index from the primary index, thereby to provide a quantification of QRS complexes.
Core Innovation
The invention provides an apparatus for QRS waveform quantifying that receives a plurality of high frequency (HF) range QRS complexes from at least one ECG lead. The HF range QRS complexes are used as input to compute multiple primary indices, and a primary analyzer calculates a first primary index from a first HF range QRS complex in a first time period and a second primary index from a second HF range QRS complex in a second time period, where the first and second time periods are different and not coinciding.
The apparatus derives a secondary index from the plurality of primary indices to provide a quantification of the QRS complexes. In particular, the secondary index is a running average of the plurality of primary indices, thereby consolidating the quantification across different, non-coinciding time periods.
Additional embodiments quantify QRS waveform behavior using sets of amplitude values representing HF range QRS complexes aligned over a time frame, and remove outward amplitude values for any given time unit. The reduction unit removes an amplitude value lying outside a region defined by a statistical function of the amplitude values, and an analyzer calculates an overall index over the sets using respective remaining amplitude values.
Other embodiments align HF QRS complexes derived from different ECG leads over time so that complexes derived from different leads but at the same time are associated together, and then calculate a primary index to provide a single quantification of the associated complexes.
Claims Coverage
The independent claims cover three inventive features: calculating primary indices from HF QRS complexes in different, non-coinciding time periods and forming a secondary index as a running average; removing outward amplitudes using a statistical-function-defined region before calculating an overall index; and aligning HF QRS complexes across multiple ECG lead locations and calculating a primary index for a single quantification.
Running average of primary indices from non-coinciding time periods
An apparatus including an input unit for receiving a plurality of high frequency (HF) range QRS complexes from at least one ECG lead, a primary analyzer calculating a plurality of primary indices from HF range QRS complexes in different and not coinciding time periods, and a secondary analyzer deriving a secondary index from the plurality of primary indices such that the secondary index is a running average of the plurality of primary indices.
Removing outward amplitudes outside a statistical-function-defined region
An apparatus including an input unit for receiving sets of amplitude values representing a plurality of high frequency (HF) range QRS complexes aligned over a time frame, a reduction unit removing at least one outward amplitude value for any given time unit from the sets wherein the reduction unit removes an amplitude value lying outside a region defined by a statistical function of the amplitude values, and an analyzer calculating an overall index over the sets using respective remaining amplitude values.
Aligning HF QRS complexes from different lead locations for a single quantification
An apparatus including an input unit for receiving a plurality of high frequency (HF) range QRS complexes obtained from a plurality of ECG leads at different locations on a subject, an alignment unit for aligning the complexes so that complexes derived from different leads but at the same time are associated together, and a primary analyzer calculating a primary index to provide a single quantification of the associated complexes.
Envelope-based primary index with statistical-function removal of out-of-region HF QRS complexes
An apparatus including an input unit for receiving a plurality of high frequency (HF) ECG range QRS complexes as respective sets of amplitude values aligned over a time frame, and a primary analyzer configured to calculate a primary index using an envelope of the QRS complexes while removing any HF QRS complex lying outside a region defined by a statistical function of the complexes.
The claims collectively define QRS waveform quantification by primary indices and a running-average secondary index over non-coinciding time periods, by removal of amplitude values outside a statistical-function-defined region before overall index calculation, and by alignment of HF QRS complexes across ECG lead locations for single quantification.
Stated Advantages
Documented Applications
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