Ocular sensor for the detection of an analyte in eye water
Inventors
MUELLER ACHIM, null • Müller, Achim
Assignees
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Publication Number
US-8452361-B2
Publication Date
2013-05-28
Expiration Date
Abstract
An ocular sensor (110) is proposed for verification of at least one analyte in an eye fluid. The ocular sensor (110) is composed of at least one sensor material which is designed to change at least one optical characteristic in the presence of the at least one analyte. Furthermore, the ocular sensor (110) comprises at least one sensor chip which has at least one integrated optical detector (122) for verification of the optical characteristic. A measurement system (166) is also proposed for verification of at least one analyte in an eye fluid, which measurement system (166) comprises an ocular sensor (110) according to the invention as well as an evaluation unit (168) which is designed to interchange information with the sensor chip (118).
Core Innovation
The invention relates to an ocular sensor for verification of at least one analyte in an eye fluid. The ocular sensor comprises at least one sensor material designed to change at least one optical characteristic in the presence of the at least one analyte, and the optical characteristic is verified by at least one integrated optical detector provided on a sensor chip.
The ocular sensor further comprises a carrier material in which the sensor chip is embedded and in direct contact with the carrier material. The carrier material comprises a material which is at least partially permeable for the analyte, and the sensor material is entirely or partially contained in the carrier material.
The sensor material is contained in the carrier material in at least one of: mixed into the carrier material, dissolved in the carrier material, implemented as an entirely or partially a component of the carrier material, or implemented in microcapsules. An evaluation unit performs information interchange with the sensor chip to support verification and determination of analyte concentration in the eye fluid.
Claims Coverage
The provided content includes one independent claim defining the ocular sensor architecture. It presents 3 inventive features.
Optical analyte-responsive sensor in permeable carrier
An ocular sensor for verification of at least one analyte in an eye fluid, having at least one sensor material designed to change at least one optical characteristic in the presence of the at least one analyte, and having a carrier material comprising a material at least partially permeable for the analyte.
Embedded sensor chip with integrated optical detector
The ocular sensor having at least one sensor chip with at least one integrated optical detector for verification of the optical characteristic, wherein the sensor chip is embedded in the carrier material and in direct contact with the carrier material.
Sensor material incorporated in carrier via multiple manners
The sensor material being entirely or partially contained in the carrier material, with the sensor material being contained in the carrier material in at least one of: mixed into the carrier material; dissolved in the carrier material; entirely or partially a component of the carrier material; and implemented in microcapsules.
The independent claim combines a sensor material that changes an optical characteristic in the presence of an analyte, an embedded sensor chip with an integrated optical detector, and a permeable carrier material that contains the sensor material in defined forms.
Stated Advantages
The evaluation unit and calibration system support verification and determination of analyte concentration in the eye fluid, with concentration accuracy and reliability improved by conventional test strips and blood glucose meters.
Documented Applications
Verification of at least one analyte in an eye fluid, including glucose as an exemplary analyte.
Use of an evaluation and calibration system with conventional test strips and blood glucose meters to improve concentration accuracy and reliability.
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