Hemostatic textile
Inventors
Fischer, Thomas H. • Eskridge, JR., E. Stan • Malloy, JR., William M. • Evans, Malloy
Assignees
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Publication Number
US-8377467-B2
Publication Date
2013-02-19
Expiration Date
Abstract
The present invention is directed to a hemostatic textile, comprising: a material comprising a combination of glass fibers and one or more secondary fibers selected from the group consisting of silk fibers; ceramic fibers; raw or regenerated bamboo fibers; cotton fibers; rayon fibers; linen fibers; ramie fibers; jute fibers; sisal fibers; flax fibers; soybean fibers; corn fibers; hemp fibers; lyocel fibers; wool; lactide and/or glycolide polymers; lactide/glycolide copolymers; silicate fibers; polyamide fibers; feldspar fibers; zeolite fibers, zeolite-containing fibers, acetate fibers; and combinations thereof; the hemostatic textile capable of activating hemostatic systems in the body when applied to a wound. Additional cofactors such as thrombin and hemostatic agents such as RL platelets, RL blood cells; fibrin, fibrinogen, and combinations thereof may also be incorporated into the textile. The invention is also directed to methods of producing the textile, and methods of using the textile to stop bleeding.
Core Innovation
The invention relates to a hemostatic textile made from a textile material comprising glass fibers co-woven or knitted with secondary fibers. The glass fibers have a diameter from 5 nanometers to 15 microns, and the secondary fibers comprise raw or regenerated bamboo fibers, including bamboo rayon fibers.
In described embodiments, the glass fibers are alumino-borosilicate glass and can be continuous filaments. The textile material can further comprise platelets bound to the glass fibers, the raw or regenerated bamboo fibers, or a combination thereof, and the textile can be provided in a sterilized package.
The disclosed textile activates hemostatic systems upon contact with a wound, with blood from the wound contacting the textile material. The patent also describes hemostatic cofactors or agents, including thrombin or a plasma fraction containing thrombin, RL platelets, RL blood cells, fibrin, and fibrinogen.
Claims Coverage
The independent claims cover hemostatic textiles with multiple inventive features centered on co-woven or knitted glass fibers and bamboo-based or rayon secondary fibers, with additional limitations including glass fiber diameter, platelets, continuous filaments, sterilized packaging, wound contact activation, and specified relative amounts.
Packaged co-woven or knitted glass fibers with raw or regenerated bamboo secondary fibers
A packaged hemostatic textile comprising a textile material comprising glass fibers co-woven or knitted with secondary fibers, wherein said textile material is within a sterilized package, and said secondary fibers comprise raw or regenerated bamboo fibers.
Glass fibers diameter constrained to 5 nanometers to 15 microns
A packaged hemostatic textile wherein said glass fibers have a diameter from 5 nanometers to 15 microns.
Continuous glass filaments with co-woven or knitted bamboo secondary fibers
A packaged hemostatic textile comprising a textile material comprising glass fibers co-woven or knitted with secondary fibers, wherein said glass fibers are continuous filaments, and said secondary fibers comprise raw or regenerated bamboo fibers.
Hemostatic systems activated by wound contact with blood in an animal or human
A hemostatic textile comprising a textile material comprising glass fiber co-woven or knitted with raw or regenerated bamboo fibers, wherein when said textile material is in contact with a wound on an animal or human and blood from the wound, hemostatic systems are activated in the animal or human.
Platelets bound to glass fibers and/or bamboo fibers
A hemostatic textile comprising a textile material comprising glass fibers co-woven or knitted with raw or regenerated bamboo fibers, further comprising platelets bound to the glass fibers, the raw or regenerated bamboo fibers, or a combination thereof.
Hemostatic textile with platelets bound and rayon secondary fibers
A hemostatic textile comprising a textile material comprising glass fibers co-woven or knitted with rayon fibers, wherein when said textile material is in contact with a wound on an animal or human and blood from the wound, hemostatic systems are activated in the animal or human, and wherein the textile material further comprises platelets bound to the glass fibers, rayon fibers, or a combination thereof.
Specified relative amounts: 65% by weight glass fibers and 35% by weight secondary fibers
A hemostatic textile comprising a textile material comprising glass fibers co-woven or knitted with secondary fibers, wherein the relative amounts of the glass fibers and the secondary fibers are 65% by weight glass fibers and 35% by weight secondary fibers, based on the total weight of the textile material.
The independent claims focus on hemostatic textiles combining co-woven or knitted glass fibers with raw or regenerated bamboo fibers, including bamboo rayon fibers, or with rayon fibers. The claims further require wound-contact activation of hemostatic systems in an animal or human, and some claims add platelets bound to the fiber components, continuous filaments, sterilized packaging, or a 65/35 glass-to-secondary fiber weight ratio.
Stated Advantages
Rapid activation of in-body hemostatic systems upon wound contact.
Dry storage with lyophilized proteins.
Documented Applications
Wound dressing bandage made from the packaged textile, including a sterilized package containing a wound dressing bandage.
Hemostatic use upon contact with a wound on an animal or human to activate hemostatic systems when blood from the wound contacts the textile material.
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