Compositions, kits and methods for nutrition supplementation
Inventors
Perrin, Philippe • Herry, Guillaume • Boyer-Joubert, Cecile
Assignees
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Publication Number
US-8168611-B1
Publication Date
2012-05-01
Expiration Date
Abstract
The present invention relates to compositions, kits and methods for the administration of various vitamin, mineral and nutrient compositions, and in a specific embodiment, the compositions, kits and methods may utilize or include twelve carbon chain fatty acids and/or twelve carbon chain acylglycerols, vitamin D, iodine, vitamin B1, vitamin B6, vitamin B12, vitamin B2, vitamin B9, vitamin B3, vitamin E, vitamin A, vitamin C, iron, zinc, copper, magnesium, omega 3 fatty acids and one or more pharmaceutically acceptable carriers.
Core Innovation
The invention provides compositions that include a defined mixture of vitamin D, lauric acid, iodine, vitamin B1, vitamin B6, vitamin B12, vitamin B2, vitamin B9, vitamin E, vitamin A, vitamin C, vitamin B3, iron, zinc, copper, magnesium, and docosahexaenoic acid (DHA), together with one or more pharmaceutically acceptable carriers. The composition is described as a nutrition supplementation composition for physiologically stressful states, including pregnancy/lactation, and as suitable for dietary supplement or prescription prenatal vitamin contexts.
Lauric acid is described in connection with twelve-carbon chain fatty acids and acylglycerols, including lauric acid, monolaurin, linderic acid, and lauroleic acid. The document also discusses esterification at the 1, 2, or 3 glycerol carbons, gives examples such as monolaurin, dilaurin, and trilaurin, and describes double-bond configuration concepts for unsaturated twelve-carbon chain fatty acids using cis/trans and E/Z configuration language.
The document further associates lauric acid with natural, synthetic, or genetically engineered sources and with oil sources selected from algae oil, Martek Algae oil, coconut oil, babassu oil, and palm kernel oil. It provides dosage-form examples such as gelcaps, including soft-gel gelcap, caplets, and kit-based administration, and connects the compositions to cited clinical or measurement studies assessing nutritional status, milk fatty-acid composition, serum 25-hydroxyvitamin D, and iodide serum.
Claims Coverage
The provided claim coverage includes one independent claim directed to a defined multivitamin/mineral composition with lauric acid and DHA, together with one or more pharmaceutically acceptable carriers. The inventive features are the specified compositional package and dependent refinements for lauric acid sourcing/derivation, dosage form, and product context.
Defined vitamin D, lauric acid, iodine, vitamin B complex, vitamins A/C/E, DHA and minerals composition
A composition consisting vitamin D in an amount of about 1000 I.U., lauric acid in an amount of about 60 mg, iodine in an amount of about 200 μg, vitamin B1 in an amount of about 1.6 mg, vitamin B6 in an amount of about 2.5 mg, vitamin B12 in an amount of about 12 μg, vitamin B2 in an amount of about 1.8 mg, vitamin B9 in an amount of about 1.0 mg, vitamin E in an amount of about 10 I.U., vitamin A in an amount of about 1100 I.U., vitamin C in an amount of about 12 mg, vitamin B3 in an amount of about 15 mg, iron in an amount of about 27 mg, zinc in an amount of about 15 mg, copper in an amount of about 2.0 mg, magnesium in an amount of about 5 mg, and docosahexaenoic acid (DHA) in an amount of about 200 mg, and one or more pharmaceutically acceptable carriers.
Lauric acid obtained from specified oil sources
The composition specifies that the lauric acid is obtained from at least one oil selected from algae oil, Martek Algae oil, coconut oil, babassu oil, and palm kernel oil.
Lauric acid derivation characterized as natural, synthetic, or genetically engineered
The composition specifies that the lauric acid is derived from a natural source, a synthetic source, or is genetically engineered.
Gelcap dosage form for the composition
The composition is provided in the dosage form of a gelcap.
Product category limited to dietary supplement or prescription prenatal vitamin
The composition is a dietary supplement or a prescription prenatal vitamin.
Overall, the claims cover a defined vitamin/mineral composition with lauric acid and DHA, with refinements for lauric acid oil sources and derivation type, and with limits to a gelcap dosage form and to dietary supplement or prescription prenatal vitamin use.
Stated Advantages
Improved compliance via one-piece gelcap or two-part kit administration is described.
Disease prevention/therapy is described as a rationale associated with the combination.
The inclusion of lauric acid/monolaurin is described as having antimicrobial effects.
Iodine deficiency prevention is described.
Antioxidant benefits are described.
Documented Applications
Nutrition supplementation in physiologically stressful states, including pregnancy/lactation, is described.
Use as a dietary supplement or as a prescription prenatal vitamin is described.
A gelcap dosage form is described for the composition.
Cited clinical/measurement studies assessing nutritional status and milk fatty-acid composition after supplementation.
Assessment in studies including serum 25-hydroxyvitamin D and iodide serum.
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