Techniques for improved automatic drug delivery performance using delivery tendencies from past delivery history and use patterns
Inventors
Lee, Joon Bok • O'Connor, Jason • Zheng, Yibin
Assignees
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Publication Number
US-12741094-B2
Publication Date
2026-09-22
Expiration Date
Abstract
Disclosed are a device, system, methods and computer-readable medium products that provide techniques to implement functionality to receive blood glucose measurements over a period of time. An average of missing blood glucose measurement values may be maintained over a predetermined time period. A count of a number of missing blood glucose measurement values over a period of time may be established. A controller may calculate a divergence of the number of missing blood glucose measurement values over the period of time from the average of missing blood glucose measurements over the predetermined time period. Based on a value of the divergence, a determination that a safety constraint for delivery of insulin is to be reduced. The safety constraint may be reduced by a predetermined percentage. An instruction to deliver an insulin dosage may be generated according to the reduced safety constraint may be forwarded to a wearable drug delivery device.
Core Innovation
The system receives a request to deliver a bolus, determines the time of day of prior user-requested boluses within a predetermined time period, and identifies the number of bolus deliveries within a predetermined segment of that period. Based on the identified number, it calculates a modified user bolus insulin dosage and, in response to a subsequent bolus request, forwards an instruction to deliver a bolus according to that dosage.
The system also calculates a bolus-uncertainty metric from the timing and frequency of prior user-requested boluses, and performs personalized safety-constraint adjustment and glucose-prediction model updates. Because the background section is not included, the specific problem being solved is not explicitly described in patent.
Claims Coverage
The claim coverage includes two inventive features across two independent claims: claim 1 covers a system, and claim 13 covers a non-transitory, computer readable storage medium embodied with programming code.
System-based modified bolus dosage
Claim 1 covers a processor that determines the time of day of prior requested boluses, identifies the number of bolus deliveries within a predetermined segment of a predetermined time period, and calculates a modified user bolus insulin dosage based on that number. In response to a subsequent bolus request, the system forwards an instruction to deliver a bolus according to the modified dosage.
Programming code for modified bolus dosage
Claim 13 covers programming code that causes a processor to determine the time of day of prior requested boluses, identify the number of bolus deliveries within a predetermined segment of a predetermined time period, and calculate a modified user bolus insulin dosage based on that number. The code causes the processor to forward an instruction for a subsequent bolus according to the modified dosage.
The two independent claims cover the same prior-bolus timing and delivery-count approach to calculating and applying a modified user bolus insulin dosage, respectively as a system and as programming code stored on a computer readable storage medium.
Stated Advantages
Not explicitly described in patent.
Documented Applications
Automated insulin-delivery systems, including an artificial pancreas application.
A personal diabetes management device that sends a bolus-request signal.
A wearable drug delivery device with a pump mechanism for delivering a bolus according to the modified user bolus insulin dosage.
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