Medicament adaptation and safety monitoring

Inventors

NARAYANASWAMI, Rangarajan

Assignees

Insulet Corp

Abstract

Disclosed are exemplary drug delivery systems that include controllers, drug delivery devices, and the like. The disclosed drug delivery system and controllers may include a processor, a user interface, a memory, and communication circuitry. An automated drug delivery algorithm is operable to receive a number of different inputs related to a user's glucose and/or ketone levels. The automated drug delivery algorithm(s) of the described drug delivery systems and controllers are operable to adjust to when a user partakes in fasting for a period of time that lasts a day or multiple days. The period of time may be a fasting event, such as a religious holiday or diet regimen. For example, the disclosed automated drug delivery algorithm(s) are operable to receive an indication of initiation of a fasting mode; and modify a drug delivery schedule based on the period of fasting or while in fasting mode.

Core Innovation

The described controller and drug delivery system receive, via a user interface, an indication of a fasting event or period of fasting for a user. Based on the period of fasting, the processor modifies a drug delivery schedule to increase a basal delivery rate for a first time threshold after receipt of the indication. The background section is not included in the supplied patent content, so the problem being solved is not explicitly described.

The described schedule includes further basal delivery rate changes around the fasting period, including maintaining a baseline value between time thresholds and reducing the rate before the fasting period ends. The processor may also deliver a bolus dosage close to the end of the fasting period. Glucose, activity, and ketone monitoring support hypoglycemia and ketone alerts.

Claims Coverage

The independent claims cover a drug-delivery controller and a drug delivery system, comprising two inventive features each utilizing a processor, user interface, memory, and communication circuitry.

The independent claims cover controller and system configurations that receive a fasting indication and increase basal delivery after receipt, with related claims addressing basal rate changes around fasting and bolus delivery near fasting completion.

Stated Advantages

Documented Applications