Tools for transurethral deployment and fixation of graft for the management and treatment of urethral strictures
Inventors
Godzich Elakkad, Chanya • Maruvada, Teja • Pia, Joseph A. • Srigiri, Shravya • Covington, Kendall • Wright, Edward James
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Assignees
MemberJohns Hopkins UniversityJohns Hopkins UniversityFounded in 1876, Johns Hopkins University is recognized as the first research university in the United States. It advances interdisciplinary education, high-impact research, and global outreach, supporting knowledge translation, technological innovation, and community partnerships. The university fosters academic excellence, innovation incubation, outreach, and inclusion across multiple campuses in Baltimore, integrating into the city's social, economic, and cultural life.
Founded in 1876, Johns Hopkins University is recognized as the first research university in the United States. It advances interdisciplinary education, high-impact research, and global outreach, supporting knowledge translation, technological innovation, and community partnerships. The university fosters academic excellence, innovation incubation, outreach, and inclusion across multiple campuses in Baltimore, integrating into the city's social, economic, and cultural life.
Publication Number
US-12697236-B2
Publication Date
2026-08-04
Expiration Date
Abstract
An embodiment in accordance with the present invention provides a device and method for the treatment of urethral stricture. The present invention places and holds a graft at an incised urethral stricture site for 5-21 days, while the graft adherences to the incised urethral stricture site. A device of the present invention includes a delivery component, a graft carrier component, and a removal component. In some embodiments, the delivery and removal components may be combined into the same device. The delivery component, the graft carrier component, and the removal component are all configured to enter and exit the urethra without trauma. A method according to an embodiment of the present invention includes harvesting a graft, loading the graft onto the graft carrier component, introducing the delivery device into the urethra with the graft carrier component and graft loaded, and delivering of the graft to the incised urethral stricture site.
Core Innovation
The invention describes a device comprising a component configured to expand when placed at a site within a lumen. The component comprises at least a first portion and a second portion, is longer than a width of the component, and expands based on the first portion and the second portion moving in a direction perpendicular to a length of the component on at least one side, away from each other.
In the device, the first portion is associated with a first set of interleaved arc components, and the second portion is associated with a second set of interleaved arc components. The first set and the second set are configured to collapse towards each other or move away from each other, and the first portion and the second portion are separate components.
Only the first portion holds a treatment material for placement at the lumen, while the second portion is configured to be in direct contact with the lumen and fixate the component within the lumen by surface characteristics of the second portion. The method comprises securing a treatment material to a first portion of a component and expanding the component at the site within the lumen with the same perpendicular movement of the first portion and the second portion.
Claims Coverage
The partial content includes two independent claims. They focus on a multi-portion expanding component for lumen placement, with treatment material held only on a first portion and fixation achieved by direct contact of a second portion using surface characteristics, together with interleaved arc component sets and perpendicular-direction expansion driven by relative movement of the portions.
Perpendicular expansion of interleaved arc multi-portion component in a lumen
A component configured to expand when placed at a site within a lumen, comprising at least a first portion and a second portion, longer than a width of the component, and expanding based on the first portion and the second portion moving in a direction perpendicular to a length of the component on at least one side, away from each other.
Treatment material on only first portion and lumen fixation by second portion surface characteristics
The first portion is associated with a first set of interleaved arc components and the second portion is associated with a second set of interleaved arc components, the first set and the second set are configured to collapse towards each other or move away from each other, the first portion and the second portion are separate components, only the first portion holds a treatment material for placement at the lumen, and the second portion is configured to be in direct contact with the lumen and fixate the component within the lumen by surface characteristics of the second portion.
Securing treatment material to first portion and expanding at a lumen site
A method comprising securing a treatment material to a first portion of a component, wherein the component comprises at least the first portion and a second portion, the first portion is associated with holding the treatment material for placement at a site within a lumen, and the component expands at the site within the lumen based on the first portion and the second portion moving in a direction perpendicular to a length of the component on at least one side, away from each other.
Fixation by second portion direct contact using surface characteristics
The first portion is associated with a first set of interleaved arc components and the second portion is associated with a second set of interleaved arc components, the first set and the second set are configured to collapse towards each other or move away from each other, the first portion and the second portion are separate components, the treatment material is secured only on the first portion for placement at the lumen, and the second portion is configured to be in direct contact with the lumen and fixate the component within the lumen by surface characteristics of the second portion.
Across the independent claims, the core inventive concept is a multi-portion component with interleaved arc component sets that expands in a direction perpendicular to the component length based on relative movement of first and second portions, with treatment material secured only to the first portion and lumen fixation provided by direct contact of the second portion via surface characteristics.
Stated Advantages
Not explicitly described in patent.
Documented Applications
Not explicitly described in patent.
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