Interested in licensing this patent?
MTEC can help explore whether this patent might be available for licensing for your application.
Publication Number
US-12661448-B2
Publication Date
2026-06-23
Expiration Date
Abstract
An injection system includes an injection system body defining a proximal opening at a proximal end thereof and a distal needle interface at a distal end thereof. The system also includes proximal and distal stopper members disposed in the injection system body, forming a proximal drug chamber between the proximal and distal stopper members and a distal drug chamber between the distal stopper member and the distal end of the injection system body. The system further includes a plunger member configured to be manually manipulated to insert the proximal stopper member relative to the injection system body. Moreover, the system includes a valve forming an openable barrier between the distal needle interface and at least a portion of the distal drug chamber. The valve is configured to allow flow from the portion of the distal drug chamber to the distal needle interface with increased pressure in the distal drug chamber.
Core Innovation
The injection system includes a single piece injection system body defining only two openings: a proximal opening at a proximal end and a distal opening at a distal end, with a distal needle interface at the distal end. A proximal stopper member and a distal stopper member are disposed in the injection system body, forming a proximal drug chamber between the proximal stopper member and the distal stopper member and a distal drug chamber between the distal stopper member and the distal end of the injection system body.
A plunger member is configured to be manipulated to insert the proximal stopper member relative to the injection system body. A valve forms an openable barrier between the distal needle interface and at least a portion of the distal drug chamber, and the valve is configured to allow flow from the distal drug chamber to the distal needle interface with increased pressure in the distal drug chamber.
The valve is disposed at the distal end of the single piece injection system body separate from the proximal stopper member and the distal stopper member, so the barrier is associated with the distal needle interface rather than the proximal stopper motion. In additional valve and fluid-conveying member configurations, the valve includes a distally facing funnel configured to guide a proximal end of a fluid conveying member through a central seal during assembly.
An elongate fluid conveying member is configured to at least partially pierce the distal stopper member to form a flow path from the distal drug chamber to the proximal drug chamber. The elongate fluid conveying member defines a circumferential shoulder, and an insert disposed in the distal stopper member includes a distally facing funnel and a pair of fingers that interfere with the circumferential shoulder to temporarily prevent distally directed motion of the distal stopper member while the flow path is open.
Claims Coverage
The independent claims define an injection system having a single piece body with only proximal and distal openings, proximal and distal stopper members that form separate proximal and distal drug chambers, a plunger that inserts the proximal stopper member, and a distal valve that forms an openable barrier between the distal drug chamber and a distal needle interface. Across the independent claims, there are three main inventive-feature groupings.
Distal openable barrier valve pressure-actuated flow to distal needle interface
An injection system in which a valve forms an openable barrier between the distal needle interface and at least a portion of the distal drug chamber, the valve allows flow from the portion of the distal drug chamber to the distal needle interface with increased pressure in the distal drug chamber, and the valve is disposed at the distal end of the single piece injection system body separate from the proximal stopper member and the distal stopper member.
Valve distally facing funnel guiding proximal end through central seal during assembly
A valve defines a distally facing funnel configured to guide a proximal end of the fluid conveying member through the central seal during assembly of the injection system.
Elongate fluid conveying member piercing flow path with insert funnel and interfering fingers
An elongate fluid conveying member configured to at least partially pierce the distal stopper member to form a flow path from the distal drug chamber to the proximal drug chamber, the elongate fluid conveying member defining a circumferential shoulder; and an insert disposed in the distal stopper member comprising a distally facing funnel and a pair of fingers configured to interfere with the circumferential shoulder to temporarily prevent distally directed motion of the distal stopper member while the flow path is open, wherein the pair of fingers are disposed proximally of the distally facing funnel.
The independent claims collectively cover an injection system in which distal delivery is governed by a valve that provides a pressure-actuated openable barrier to a distal needle interface, with optional valve funnel guidance for passing a fluid conveying member through a central seal during assembly, and with an elongate fluid conveying member piercing arrangement supported by an insert whose distally facing funnel and interfering fingers temporarily prevent distally directed motion of the distal stopper member while the flow path remains open.
Stated Advantages
Not explicitly described in patent.
Documented Applications
Not explicitly described in patent.
Interested in licensing this patent?