Dynamic adaptation of radiotherapy treatment plans
Inventors
Lachaine, Martin Emile • Falco, Tony
Assignees
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Publication Number
US-12623092-B2
Publication Date
2026-05-12
Expiration Date
Abstract
A reference radiotherapy treatment plan having a plurality of control points, such as a sequence of gantry angles, aperture leaf positions, and intensity weights, can be adapted during the radiotherapy treatment session. Treatment imaging data of a patient may be obtained during the radiotherapy treatment session and one or more parameters may be determined using the treatment imaging data. Then, a current radiotherapy treatment plan may be generated based on the parameter(s). The reference radiotherapy treatment plan for the radiotherapy treatment session may be modified during the radiotherapy treatment session by updating one of the plurality of control points of the reference radiotherapy treatment plan with a control point of a current radiotherapy treatment plan, which may compensate for patient deformations during the delivery of radiotherapy treatment, or intrafraction patient deformations and thereby improve the delivery accuracy and efficacy of radiation doses to a patient undergoing radiotherapy treatment.
Core Innovation
The claims describe adapting a reference radiotherapy treatment plan during a radiotherapy treatment session. Treatment imaging data is used to determine at least one parameter representing an anatomical state and generate a current radiotherapy treatment plan. A control point of the reference plan is updated with a control point of the current plan. The method utilizes a trained model relating training parameters to plans generated for corresponding training images via a training regression.
The claimed radiotherapy system acquires measurements during treatment and uses computational loops operating at independent rates to process anatomical parameters and treatment plans. A first computational loop generates a parameter representing the subject's anatomical state, while a second computational loop generates the current treatment plan. Radiation is delivered to an anatomical region of interest using the current plan, compensating for anatomy changes during the treatment session.
Claims Coverage
The provided claims include two independent claims covering a computer-implemented method and a radiotherapy system, summarized by two inventive features.
In-session treatment plan adaptation using a trained model
Claim 1 obtains treatment imaging data during a radiotherapy treatment session, determines at least one parameter using that data, and generates a current radiotherapy treatment plan based on the parameter. It modifies the reference plan by updating a control point of the reference plan with a control point of the current plan. The trained model includes training images representing potential anatomical states, corresponding training parameters, training radiotherapy treatment plans, and a training regression between the parameters and plans.
Radiotherapy system with independent-rate computational loops
Claim 18 covers an image acquisition device, a processor, and a radiotherapy device. The processor executes a first computational loop to generate a parameter representing an anatomical state and a second computational loop, operating at a rate independent of the first, to generate a current radiotherapy treatment plan. The system updates a control point of the reference plan with a control point of the current plan and delivers radiation to an anatomical region of interest using the current plan.
Together, the independent claims cover in-session plan adaptation supported by treatment measurements and a trained model, and a radiotherapy system that generates and applies an updated plan using computational loops operating at independent rates.
Stated Advantages
Compensates for anatomy changes during treatment to improve the accuracy and efficacy of radiation-dose delivery.
Documented Applications
Adaptation and use of a reference radiotherapy treatment plan during a radiotherapy treatment session, wherein a radiotherapy device delivers radiation to an anatomical region of interest using the current radiotherapy treatment plan.
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