Electroporation device with detachable needle array with lock-out system

Inventors

Stadelmann, Beat • Kemmerrer, Stephen • Campillo-Agusti, Alejandro • Ho, Eduardo • Lovell, Nathan • Masterson, Steven

Assignees

Inovio Pharmaceuticals Inc

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Publication Number

US-12623074-B2

Patent

Publication Date

2026-05-12

Expiration Date


Abstract

An electroporation device with a needle array removably attached thereto, the needle array having a body, a shroud movable with respect to the body between a rest position and one or more actuated positions, and an auto-lock assembly. Where the auto-lock assembly is adjustable between a locked configuration, where the shroud is not movable with respect to the body, and an unlocked configuration, where the shroud is movable with respect to the body, and where biasing the shroud from the rest position to the one or more actuated positions and back to the rest position adjusts the auto-lock from the unlocked configuration to the locked configuration.

Core Innovation

The invention provides a single-use needle array or needle device for an electroporation device comprising a body member and a shroud movable axially between a rest position and one or more actuated positions. An auto-lock includes a resilient body coupled to the shroud that engages a contact surface at rest and flexes laterally during axial shroud movement. This lateral flexing moves the second end or locking tip of the resilient body into engagement with a locking surface.

The resilient body is spaced radially from the central axis, and the locking tip extends radially inward toward the axis. The arrangement incorporates a Z-shaped locking surface configured to engage the resilient body or locking tip after axial shroud movement. Upon returning to the rest position, the auto-lock blocks the shroud from returning to an actuated position and prevents re-exposure of the needle array.

Claims Coverage

The two independent claims cover a single-use needle array and a single-use needle device featuring two inventive features.

Movable shroud with resilient-body auto-lock

A single-use needle array for an electroporation device, comprising a body member, a shroud movable axially between a rest position and one or more actuated positions, and an auto-lock with a resilient body coupled to the shroud that engages a contact surface at rest and flexes laterally during axial shroud movement so that its second end engages a locking surface.

Resilient body with a locking tip

A single-use needle device comprising a body member with a contact surface and a locking surface, and a movable shroud with a resilient body defining a locking tip at its second end extending radially inward toward the axis, wherein the locking tip engages the contact surface at rest and engages the locking surface after axial shroud movement causes lateral flexing.

Together, the independent claims cover configurations of a single-use needle array and needle device using shroud movement to transition a resilient body or locking tip from a contact surface to a locking surface to block return to an actuated position.

Stated Advantages

The auto-lock prevents re-exposure of the electrodes and needle array when the shroud returns to rest.

Documented Applications

A single-use needle array or needle device for an electroporation device.

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