Acquisition device to limit leakage current in electrophysiological signal recording devices
Inventors
Guimera Brunet, Antón • Re Blanco, Lucía • MASVIDAL CODINA, Eduard • Villa Sanz, Rosa • ILLA VILA, Xavier • GARRIDO ARIZA, José Antonio • SCHAEFER, Nathan • García Cortadella, Ramón
Assignees
Consejo Superior de Investigaciones Científicas • Institució Catalana de Recerca i Estudis Avançats • Institut Català de Nanociència i Nanotecnologia • Centro de Investigación Biomédica en Red
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Publication Number
US-12622624-B2
Publication Date
2026-05-12
Expiration Date
Abstract
The device limits the leakage current in an electronic system for recording electrophysiological signals, where the transducer element is an active device, the device comprising an active transducer (1), intended to contact a human tissue, connected to a transimpedance amplifier (2), and a first resistor (6) connected parallel to the transimpedance amplifier (2), an alternate voltage source (7) and a direct voltage source (8), both connected to the active transducer (1), a first capacitor (3) connected between the alternate voltage source (7) and the active transducer (1), a second resistor (4) connected between the direct voltage source (8) and the active transducer (1), parallel with the first capacitor (3) and the alternate voltage source (7), and a second capacitor (5), connected between the active transducer (1) and the transimpedance amplifier (2).
Core Innovation
The document describes an acquisition device to limit leakage current in electrophysiological signal recording devices. The device includes a first active transducer connected to a first transimpedance amplifier and intended to contact a body tissue. The acquisition device uses an AC-coupled acquisition approach that limits patient leakage current even under electronics breakdown, by managing leakage-current paths associated with the active transducer’s electrical coupling.
The acquisition device uses an alternate voltage source connected to the first active transducer and opposite to the first transimpedance amplifier, together with a direct voltage source connected to the first active transducer in parallel with the alternate voltage source. A first capacitor is connected between the alternate voltage source and the first active transducer, a first resistor is connected between the direct voltage source and the first active transducer, and a second capacitor is connected between the first active transducer and the first transimpedance amplifier to limit leakage current transferred toward the transimpedance amplifier.
For implementations, the document associates the active transducer with a solution-gated graphene FET as a preferred example (gSGFET) and states that the first resistor can be set relative to a maximum supply voltage (Vsupp) to control leakage current in a normal operation condition and in a simple failure condition. The approach is extended to multiplexed arrays, including architectures that share a first capacitor/second resistor group across transducers and include per-transducer second capacitors and per-row connections to transimpedance amplifiers.
Claims Coverage
The partial content provides three independent claims, centered on leakage-current limiting in electrophysiological acquisition using paired AC and DC bias sources with a first capacitor and parallel resistor/capacitor network, a multiple active transducer variant with additional module components, and an m×n multiplexed array with common capacitor/resistor/voltage-source networks and specified parallel connectivity relationships.
Acquisition device with alternate and direct voltage sources and capacitor-resistor leakage limiting
An acquisition device to limit leakage current in electrophysiological signal recording devices comprising a first active transducer connected to a first transimpedance amplifier and intended to contact a body tissue; an alternate voltage source connected to the first active transducer and opposite to the first transimpedance amplifier; a direct voltage source connected to the first active transducer, parallel to the alternate voltage source; a first capacitor between the alternate voltage source and the first active transducer; a first resistor between the direct voltage source and the first active transducer, parallel to the first capacitor and the alternate voltage source; and a second capacitor between the first active transducer and the first transimpedance amplifier.
Multiple active transducer acquisition device with module-level transimpedance components
A multiple active transducer acquisition device comprising an acquisition device including a first active transducer connected to a first transimpedance amplifier and intended to contact a body tissue; an alternate voltage source connected to the first active transducer and opposite to the first transimpedance amplifier; a direct voltage source connected to the first active transducer, parallel to the alternate voltage source; a first capacitor between the alternate voltage source and the first active transducer; a first resistor between the direct voltage source and the first active transducer, parallel to the first capacitor and the alternate voltage source; and a second capacitor between the first active transducer and the first transimpedance amplifier; and one or more acquisition modules each comprising a second active transducer, a third capacitor connected to the second active transducer, a second transimpedance amplifier connected to the third capacitor, and a second resistor connected in parallel with the second transimpedance amplifier.
Multiplexed array acquisition device with common capacitor and resistor networks
A multiplexed array acquisition device comprising an m×n active transducers matrix with m columns and n rows, with m common first capacitors, m common first resistors, m common alternate voltage sources, and m common direct voltage sources; n common second capacitors, n common transimpedance amplifiers, and n common second resistors; wherein each common first resistor is connected in parallel to each common first capacitor, each common first capacitor is connected to each common alternate voltage source and each common first resistor is connected to each common direct voltage source; and wherein active transducers in each column are connected to each common first capacitor and each common first resistor, and active transducers in each row are connected to each common second capacitor.
Across the independent claims, the inventive coverage centers on leakage-current limiting by connecting a first active transducer to a transimpedance amplifier while applying alternate and direct voltage sources in parallel with a first capacitor and a parallel first resistor/capacitor arrangement, plus a second capacitor between the active transducer and the transimpedance amplifier. The coverage further extends to multiple active transducer modules and to an m×n multiplexed array using common first and second capacitor/resistor networks with specified column-wise and row-wise connectivity to shared voltage sources and transimpedance amplifiers.
Stated Advantages
Limits patient leakage current even under electronics breakdown.
Controls leakage current in electrophysiological signal recording by biasing with alternate and direct voltage sources and using the recited capacitor/resistor configuration.
Documented Applications
Electrophysiological signal recording devices, including multiplexed arrays and multiplexed acquisition architectures with m×n active transducers and transimpedance amplifier sharing across rows.
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