Method for carrying out a P/V maneuver which automatically prevents an overdilation of the lungs, and ventilation device designed to carry out the method
Inventors
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Assignees
Member
Hamilton Medical Inc.Hamilton Medical is focused on the development, manufacturing, and training for advanced respiratory support technologies. The company provides intelligent ventilation systems, high flow oxygen therapy, noninvasive ventilation, and educational platforms for healthcare professionals. Their offerings emphasize patient safety, data-driven decision making, and regulatory compliance across intensive care, transport, neonatal, and emergency settings.
Hamilton Medical is focused on the development, manufacturing, and training for advanced respiratory support technologies. The company provides intelligent ventilation systems, high flow oxygen therapy, noninvasive ventilation, and educational platforms for healthcare professionals. Their offerings emphasize patient safety, data-driven decision making, and regulatory compliance across intensive care, transport, neonatal, and emergency settings.
Publication Number
US-12616809-B2
Publication Date
2026-05-05
Expiration Date
Abstract
A ventilation device for artificially ventilating a patient, having a controller to actuate a flow modifying device for a P/V maneuver while wherein the pressure of respiratory gas is increased during an inspiration phase, wherein respiratory gas passively flows out of the patient during an expiration phase after the pressure increase is terminated, for a plurality of respiratory gas pressures, the respective maneuver respiratory gas volume in the patient from the P/V maneuver is ascertained in connection with the respiratory gas pressure during inspiration and expiration phases; the controller ascertaining a sequence of lung compliance values during the inspiration phase, ascertain a reference compliance value, based on the reference compliance value, determine a termination compliance value in the form of a threshold value as a termination criterion for the inspiration phase, and—terminate the inspiration phase if the termination compliance value is reached or exceeded.
Core Innovation
A ventilation device for artificial ventilation of a patient provides an inspiratory respiratory gas during an inspiration phase under elevated respiratory gas pressure and allows passively flowing expiratory respiratory gas out of the patient after completion of the pressure elevation. During both the inspiration phase and the expiration phase, for a plurality of respiratory gas pressures, the respective maneuver respiratory gas volume present in the patient due to the P/V maneuver is determined in correlation with the prevailing respiratory gas pressure. The device acquires inspiratory and expiratory respiratory gas flows and inspiratory and expiratory respiratory gas pressures in a respiratory gas line arrangement and uses these signals to determine pulmonary compliance values as a sequence versus respiratory gas pressure.
The control device determines a sequence of compliance values each representing a pulmonary compliance of the lung of the patient and determines a reference compliance value in accordance with the sequence. Starting from the reference compliance value, the control device determines a termination compliance value which is quantitatively different from the reference compliance value as a termination threshold value. The control device terminates the inspiration phase when the termination compliance value is reached or crossed.
The disclosed approach further relates the inspiratory and expiratory P/V behavior to pulmonary recruitability of pulmonary tissue by using compliance-based processing of the maneuver over pressure end-regions. A volume ratio value is determined based on quantitatively greatest differences and differences between maneuver respiratory gas volumes in defined lower and upper end-regions of the traversed respiratory gas pressure range. A hysteresis ratio value is determined based on the size of a hysteresis region between expiratory and inspiratory maneuver respiratory gas volumes as a function of respiratory gas pressure, using an enclosing rectangle defined by corresponding start and termination-associated pressure bounds.
Claims Coverage
The partial content provides two independent claims, covering a ventilation device and a method for performing a P/V maneuver, each centered on determining compliance across multiple respiratory gas pressures and terminating the inspiration phase when a termination compliance value is reached or crossed.
Termination of inspiration phase using compliance threshold
A ventilation device performs a P/V maneuver in an inspiration phase by supplying respiratory gas to a patient under elevated respiratory gas pressure and in an expiration phase after completion of the pressure elevation where the expiratory flow passively flows out of the patient, determines for a plurality of respiratory gas pressures maneuver respiratory gas volume present in the patient in correlation with prevailing respiratory gas pressure, determines a sequence of compliance values during the inspiration phase, determines a reference compliance value in accordance with the sequence, determines a termination compliance value quantitatively different from the reference as a termination threshold value, and terminates the inspiration phase when the termination compliance value is reached or crossed.
P/V maneuver compliance-based termination for recruitability data
A method for performing a P/V maneuver comprises performing a P/V maneuver and supplying inspiratory respiratory gas to a patient in an inspiration phase under elevated respiratory gas pressure, determining during the inspiration phase inspiratory maneuver respiratory gas volume supplied during the inspiration phase or an inspiratory maneuver volume flow of inspiratory respiratory gas and determining the respiratory gas pressure, determining a sequence of compliance values representing a pulmonary compliance of the lung of the patient, determining a reference compliance value in accordance with the sequence of compliance values, determining a termination compliance value quantitatively different from the reference as a termination threshold value, and terminating the inspiration phase when the termination compliance value is reached or crossed.
Ratio-based compliance calculation from pressure-change with volume-change and/or flow
The control device determines the sequence of compliance values as ratios at the same respiratory gas pressure using a ratio of a volume-change value to a pressure-change value and/or a ratio of a flow value to the pressure-change value, where the volume change value represents a temporal change in the maneuver respiratory gas volume and where the flow value represents the inspiratory respiratory gas flow.
Reference compliance selection as quantitatively largest compliance
The control device selects the quantitatively largest compliance value from a sequence where compliance values first become quantitatively larger and subsequently smaller, and uses that as the reference compliance value.
Termination compliance as 85% to 91% of reference compliance
The termination compliance value equals 85% to 91% of the reference compliance values.
Volume ratio calculation using greatest P/V difference and pressure end-regions
A volume ratio value is determined based on a quantitatively greatest difference between expiratory and inspiratory maneuver respiratory gas volumes for a respiratory gas pressure and on a difference between maneuver respiratory gas volume values in an upper end-region and a lower end-region of the traversed respiratory gas pressure range.
Hysteresis ratio calculation from hysteresis area using an enclosing rectangle
A hysteresis ratio value is determined from a hysteresis area size in a graph of expiratory and inspiratory maneuver respiratory gas volumes versus respiratory gas pressure during a P/V maneuver, using an enclosing rectangle defined by pressure bounds with corresponding respiratory gas volume values at selected lower and upper pressure points.
Across the independent device and method claims, the shared inventive core is compliance-driven termination of the inspiration phase during a P/V maneuver, using a termination compliance value defined as quantitatively different from a reference compliance value and terminated when reached or crossed. The partial dependent claims further add specific compliance computation using ratio-based pressure-change with volume-change and/or flow, reference selection as the peak compliance from an increase-then-decrease sequence, a specific termination-compliance range relative to the reference, and recruitability-related metrics including volume ratio and hysteresis ratio computed from defined pressure end-regions of inspiratory/expiratory P/V behavior.
Stated Advantages
Preventing pulmonary overdilation and improving diagnostic quality of P/V data.
Documented Applications
Establishing data for assessing the recruitability of pulmonary tissue via recruitability/dilatability indicators derived from inspiratory/expiratory P/V behavior metrics.
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