Personal cleansing composition with an organic acid having a pKa greater than 2.7
Inventors
Wei, Karl Shiqing • ZHANG, Lesheng • Wu, Xiaojian • YU, Hechuan • MEYERS, Jessa Leigh
Assignees
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Publication Number
US-12576019-B2
Publication Date
2026-03-17
Expiration Date
Abstract
A personal cleansing composition includes from about 1% to about 15% of an anionic surfactant by weight of the composition, wherein the anionic surfactant comprises sodium laureth(n) sulfate (SLEnS), wherein n is the average moles of ethoxylation, wherein n equals to 1, 2 or 3; from about 0.01% to about 1% of an organic acid having a pKa greater than about 2.7, or a cosmetically acceptable salt thereof, or a mixture thereof, by weight of the composition; and wherein the pH of the personal cleansing composition is from about 5.0 to about 6.5.
Core Innovation
The invention relates to personal cleansing compositions for non-therapeutic, rinse-off skin treatment. The compositions comprise anionic surfactants and an organic acid having a pKa greater than 2.7, formulated at a pH about 5.0 to 6.5, including embodiments at lower pH down to about 3.0. The compositions include sodium laureth(n) sulfate where n equals 1, 2, or 3, and low levels of an organic acid.
In particular, the compositions are body wash or body gel formulations that further comprise cocamidopropyl betaine as a surfactant component. A specific organic acid is disclosed as 2-pyrrolidone-5-carboxylic acid, also referred to as pidolic acid/PCA, at low levels. The stated formulation goal is to support skin acid mantle buffering and maintain or improve the skin barrier and natural moisturizing factors.
The document also discloses that the compositions support the skin’s natural antimicrobial and barrier defense, with performance especially discussed against Staphylococcus aureus. Test methods and comparisons are described, including delta detection time and delta skin pH measurements, and the compositions are associated with improved performance versus comparative cleansers lacking the pKa>2.7 organic acid and versus pH variation. Residual antimicrobial efficacy is described as occurring over multiple skin layers for up to 12 hours, with optional antimicrobial active such as piroxctone olamine disclosed as an optional component.
Claims Coverage
The independent claim covers one core inventive composition concept comprising a defined anionic surfactant system, a low level of a pKa-defined organic acid component, and a defined pH range for a body wash or body gel, further including cocamidopropyl betaine. The independent claim includes four inventive features, with dependent claims refining additional formulation constraints and a non-therapeutic use method.
Personal cleansing composition with sodium laureth(n) sulfate
A personal cleansing composition comprising from about 9% to 10% of an anionic surfactant by weight, wherein the anionic surfactant comprises sodium laureth(n) sulfate and n equals 1, 2, or 3, and wherein the personal cleansing composition is a body wash or a body gel.
Low level of organic acid comprising 2-pyrrolidone-5-carboxylic acid
A personal cleansing composition comprising from about 0.01% to about 1% of an organic acid by weight, wherein the organic acid comprises 2-pyrrolidone-5-carboxylic acid, with the pH of the composition from about 5.0 to about 5.5.
Cocamidopropyl betaine as additional surfactant component
A personal cleansing composition further comprising from about 1% to about 15% of cocamidopropyl betaine.
Non-therapeutic apply-and-rinse skin use against bacteria including Staphylococcus aureus
A non-therapeutic method for helping human skin maintain or enhance its natural defensive ability against bacteria, including Staphylococcus aureus, comprising applying the personal cleansing composition to the skin and then rinsing off the composition.
Overall, the claim set centers on a body wash or body gel formulation that uses sodium laureth(n) sulfate (n=1–3) at defined levels, includes a low level of 2-pyrrolidone-5-carboxylic acid, constrains the pH to about 5.0–5.5, and adds cocamidopropyl betaine. Dependent claims further refine formulation ranges and include a non-therapeutic apply-and-rinse method aimed at supporting skin’s natural defensive ability against bacteria including Staphylococcus aureus.
Stated Advantages
Helps human skin maintain, or enhance, its natural defensive ability against bacteria, including Staphylococcus aureus.
Supports skin acid mantle buffering and maintenance or improvement of skin barrier and natural moisturizing factors (NMF).
Provides improved performance versus comparative cleansers lacking the pKa>2.7 organic acid and versus pH variations, as indicated by delta detection time and delta skin pH measurements.
Provides multiple-layer residual antimicrobial efficacy over up to 12 hours.
Documented Applications
Non-therapeutic method for helping human skin maintain or enhance its natural defensive ability against bacteria, including Staphylococcus aureus, comprising applying a body wash/body gel personal cleansing composition and rinsing off the composition.
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